Syntheses and biological activities of novel 2-methoxyestradiol analogs, 2-fluoroethoxyestradiol and 2-fluoropropanoxyestradiol, and a radiosynthesis of 2-[18F]fluoroethoxyestradiol for positron emission tomography

Nuclear Medicine and Biology

Volumn 35, Issue 5, 2008, Pages 615-622

  Mun, Jiyoung ^a   Wang, Yuefang ^a   Voll, Ronald J ^a   Escuin Borras, Daniel ^b   Giannakakou, Paraskevi ^b   Goodman, Mark M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

2 18F Fluoroethoxyestradiol; 2 Fluoroethoxyestradiol; 2 Fluoropropanoxyestradiol; 2 Methoxyestradiol; PET

Indexed keywords

2 FLUOROETHOXYESTRADIOL; 2 FLUOROPROPANOXYESTRADIOL; 2 METHOXYESTRADIOL; FLUORINE 18; FLUOROETHOXYESTRADIOL F 18; TRACER;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEPOLYMERIZATION; DOWN REGULATION; DRUG CYTOTOXICITY; GLIOMA; HUMAN; HUMAN CELL; MASS SPECTROMETER; MICROTUBULE; MOLECULE; OVARY CARCINOMA; POSITRON EMISSION TOMOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

CELL LINE, TUMOR; DOWN-REGULATION; ESTRADIOL; FEMALE; FLUORINE RADIOISOTOPES; GLIOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INDICATORS AND REAGENTS; ISOTOPE LABELING; MAGNETIC RESONANCE SPECTROSCOPY; MICROTUBULES; OVARIAN NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; QUALITY CONTROL; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

EID: 45449100536     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.04.003     Document Type: Article

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