Domain-domain interaction of P-Rex1 is essential for the activation and inhibition by G protein βγ subunits and PKA

Cellular Signalling

Volumn 20, Issue 8, 2008, Pages 1545-1554

  Urano, Daisuke ^a   Nakata, Asuka ^a   Mizuno, Norikazu ^a   Tago, Kenji ^a   Itoh, Hiroshi ^a  

^a Graduate School of Biological Sciences   (Japan)

Author keywords

G ; Guanine nucleotide exchange factor; Heterotrimeric G protein; P Rex1; PKA; Rac

Indexed keywords

ACTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MUTANT PROTEIN; PROTEIN P REX1; RECOMBINANT PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; METHODOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; SURFACE PLASMON RESONANCE;

ANIMALS; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MICROFILAMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 45449098229     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2008.04.009     Document Type: Article

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