Mice carrying the Szt1 mutation exhibit increased seizure susceptibility and altered sensitivity to compounds acting at the M-channel

Epilepsia

Volumn 45, Issue 9, 2004, Pages 1009-1016

  Otto, James F ^a   Yang, Yan ^b   Frankel, Wayne N ^b   Wilcox, Karen S ^a   White, H Steve ^a  

^a UNIVERSITY OF UTAH   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

CHRNA4; Electroconvulsive threshold; KCNQ2; M current; Seizure susceptibility

Indexed keywords

LINOPIRDINE; NICOTINIC RECEPTOR; POTASSIUM CHANNEL; RETIGABINE;

ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG DOSE; DRUG EFFECT; FEMALE; GENE DELETION; GENE MUTATION; HEMIZYGOSITY; HINDLIMB; MALE; MEDICAL ASSESSMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SEIZURE SUSCEPTIBILITY; STIMULATION;

ANIMALS; ANTICONVULSANTS; CARBAMATES; DISEASE MODELS, ANIMAL; ELECTROSHOCK; FEMALE; GENETIC PREDISPOSITION TO DISEASE; INDOLES; KCNQ2 POTASSIUM CHANNEL; KCNQ3 POTASSIUM CHANNEL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, MUTANT STRAINS; MUTATION; NERVE TISSUE PROTEINS; PHENYLENEDIAMINES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PYRIDINES; RECEPTORS, NICOTINIC; SEIZURES; SEQUENCE DELETION;

EID: 4544384631     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0013-9580.2004.65703.x     Document Type: Article

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