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Volumn 499, Issue 3, 2004, Pages 325-333

Deletion of inducible nitric oxide synthase decreases mesenteric vascular responsiveness in portal hypertensive mice

Author keywords

eNOS knockout; iNOS; iNOS knockout; l NAME; mesenteric artery, mouse; Nitric oxide; NOS 2 knockout; NOS 3 knockout; Portal hypertension

Indexed keywords

ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; POTASSIUM CHLORIDE;

EID: 4544308276     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.08.001     Document Type: Article
Times cited : (6)

References (55)
  • 1
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • W.K. Alderton, C.E. Cooper, and R.G. Knowles Nitric oxide synthases: structure, function and inhibition Biochem. J. 357 2001 593 615
    • (2001) Biochem. J. , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 2
    • 0021522551 scopus 로고
    • Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension
    • J.N. Benoit, J.A. Barrowman, S.L. Harper, P.R. Kvietys, and D.N. Granger Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension Am. J. Physiol. 247 1984 G486 G493
    • (1984) Am. J. Physiol. , vol.247
    • Benoit, J.N.1    Barrowman, J.A.2    Harper, S.L.3    Kvietys, P.R.4    Granger, D.N.5
  • 3
    • 0043237261 scopus 로고    scopus 로고
    • Hepatic and mesenteric nitric oxide synthase expression in a rat model of CCl4-induced cirrhosis
    • E.K. Bhimani, F. Serracino-Inglott, A.I. Sarela, J.J. Batten, and R.T. Mathie Hepatic and mesenteric nitric oxide synthase expression in a rat model of CCl4-induced cirrhosis J. Surg. Res. 113 2003 172 178
    • (2003) J. Surg. Res. , vol.113 , pp. 172-178
    • Bhimani, E.K.1    Serracino-Inglott, F.2    Sarela, A.I.3    Batten, J.J.4    Mathie, R.T.5
  • 4
    • 0035865827 scopus 로고    scopus 로고
    • Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice
    • Z. Bian, Z.Q. Yan, G.K. Hansson, P. Thoren, and S. Normark Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice J. Infect. Dis. 183 2001 609 612
    • (2001) J. Infect. Dis. , vol.183 , pp. 609-612
    • Bian, Z.1    Yan, Z.Q.2    Hansson, G.K.3    Thoren, P.4    Normark, S.5
  • 6
    • 0033774753 scopus 로고    scopus 로고
    • Influence of hypertension on nitric oxide synthase expression and vascular effects of lipopolysaccharide in rat mesenteric arteries
    • A.M. Briones, M.J. Alonso, J. Marin, G. Balfagon, and M. Salaices Influence of hypertension on nitric oxide synthase expression and vascular effects of lipopolysaccharide in rat mesenteric arteries Br. J. Pharmacol. 131 2000 185 194
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 185-194
    • Briones, A.M.1    Alonso, M.J.2    Marin, J.3    Balfagon, G.4    Salaices, M.5
  • 8
    • 0028842598 scopus 로고
    • Investigations of the function of the vascular endothelium in portal hypertensive rats
    • T. Cawley, E. Breslin, J. Geraghty, H. Osborne, and J.R. Docherty Investigations of the function of the vascular endothelium in portal hypertensive rats Pharmacology 51 1995 381 390
    • (1995) Pharmacology , vol.51 , pp. 381-390
    • Cawley, T.1    Breslin, E.2    Geraghty, J.3    Osborne, H.4    Docherty, J.R.5
  • 9
    • 0028941363 scopus 로고
    • Effects of portal hypertension on responsiveness of rat mesenteric artery and aorta
    • T. Cawley, J. Geraghty, H. Osborne, and J.R. Docherty Effects of portal hypertension on responsiveness of rat mesenteric artery and aorta Br. J. Pharmacol. 114 1995 791 796
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 791-796
    • Cawley, T.1    Geraghty, J.2    Osborne, H.3    Docherty, J.R.4
  • 10
    • 0032919816 scopus 로고    scopus 로고
    • Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice
    • T. Chataigneau, M. Feletou, P.L. Huang, M.C. Fishman, J. Duhault, and P.M. Vanhoutte Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice Br. J. Pharmacol. 126 1999 219 226
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 219-226
    • Chataigneau, T.1    Feletou, M.2    Huang, P.L.3    Fishman, M.C.4    Duhault, J.5    Vanhoutte, P.M.6
  • 11
    • 0032903759 scopus 로고    scopus 로고
    • Portal hypertension increases vasoconstrictor responsiveness of rat aorta
    • C. Connolly, T. Cawley, P.A. McCormick, and J.R. Docherty Portal hypertension increases vasoconstrictor responsiveness of rat aorta Clin. Sci. 96 1999 41 47
    • (1999) Clin. Sci. , vol.96 , pp. 41-47
    • Connolly, C.1    Cawley, T.2    McCormick, P.A.3    Docherty, J.R.4
  • 12
    • 0022510527 scopus 로고
    • Hypersensitivity of mesenteric veins to 5-hydroxytryptamine- and ketanserin-induced reduction of portal pressure in portal hypertensive rats
    • S.A. Cummings, R.J. Groszmann, and A.J. Kaumann Hypersensitivity of mesenteric veins to 5-hydroxytryptamine- and ketanserin-induced reduction of portal pressure in portal hypertensive rats Br. J. Pharmacol. 89 1986 501 513
    • (1986) Br. J. Pharmacol. , vol.89 , pp. 501-513
    • Cummings, S.A.1    Groszmann, R.J.2    Kaumann, A.J.3
  • 15
    • 0019822895 scopus 로고
    • Blunted pressor response to angiotensin and sympathomimetic amines in the bile duct ligated dog
    • J.P.M. Finberg, H.A. Syrop, and O.S. Better Blunted pressor response to angiotensin and sympathomimetic amines in the bile duct ligated dog Clin. Sci. 61 1981 535 539
    • (1981) Clin. Sci. , vol.61 , pp. 535-539
    • Finberg, J.P.M.1    Syrop, H.A.2    Better, O.S.3
  • 16
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle cells by acetylcholine
    • R.F. Furchgott, and J.V. Zawadzki The obligatory role of endothelial cells in the relaxation of arterial smooth muscle cells by acetylcholine Nature 288 1980 373 376
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 17
    • 0026569512 scopus 로고
    • Evidence that nitric oxide does not mediate the hyperpolarisation and relaxation to acetylcholine in the rat small mesenteric artery
    • C.J. Garland, and G.A. McPherson Evidence that nitric oxide does not mediate the hyperpolarisation and relaxation to acetylcholine in the rat small mesenteric artery Br. J. Pharmacol. 105 1992 429 435
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 429-435
    • Garland, C.J.1    McPherson, G.A.2
  • 18
    • 0028835749 scopus 로고
    • Endothelium-dependent hyperpolarization: A role in the control of vascular tone
    • C.J. Garland, F. Plane, B.K. Kemp, and T.M. Cocks Endothelium-dependent hyperpolarization: a role in the control of vascular tone Trends Pharmacol. Sci. 16 1995 23 30
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 23-30
    • Garland, C.J.1    Plane, F.2    Kemp, B.K.3    Cocks, T.M.4
  • 19
    • 0024379617 scopus 로고
    • Portal vein pressure and portasystemic shunting in experimental portal hypertension
    • J.G. Geraghty, W.J. Angerson, and D.C. Carter Portal vein pressure and portasystemic shunting in experimental portal hypertension Am. J. Physiol. 257 1989 G52 G57
    • (1989) Am. J. Physiol. , vol.257
    • Geraghty, J.G.1    Angerson, W.J.2    Carter, D.C.3
  • 20
    • 0026641580 scopus 로고
    • The pathophysiology and pharmacological treatment of portal hypertension
    • R.D. Grose, and P.C. Hayes The pathophysiology and pharmacological treatment of portal hypertension Aliment. Pharmacol. Ther. 6 1992 521 540
    • (1992) Aliment. Pharmacol. Ther. , vol.6 , pp. 521-540
    • Grose, R.D.1    Hayes, P.C.2
  • 21
    • 0013551755 scopus 로고    scopus 로고
    • Hyporesponsiveness to α-adrenoceptor agonists in cirrhotic patients is not evident when human hepatic and mesenteric arteries are studied in vitro
    • P.W.F. Hadoke, J.F. Dillon, S.W. Walker, B.C. Williams, T.G. John, and P.C. Hayes Hyporesponsiveness to α-adrenoceptor agonists in cirrhotic patients is not evident when human hepatic and mesenteric arteries are studied in vitro Br. J. Pharmacol. 117 1996 111P
    • (1996) Br. J. Pharmacol. , vol.117
    • Hadoke, P.W.F.1    Dillon, J.F.2    Walker, S.W.3    Williams, B.C.4    John, T.G.5    Hayes, P.C.6
  • 22
    • 0030609135 scopus 로고    scopus 로고
    • 1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery
    • 1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery Br. J. Pharmacol. 122 1997 849 858
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 849-858
    • Hussain, M.1    Marshall, I.2
  • 23
    • 0032758826 scopus 로고    scopus 로고
    • Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signaling in mouse thoracic aorta
    • M.B. Hussain, A.J. Hobbs, and R.J. MacAllister Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signaling in mouse thoracic aorta Br. J. Pharmacol. 128 1999 1082 1088
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1082-1088
    • Hussain, M.B.1    Hobbs, A.J.2    MacAllister, R.J.3
  • 24
    • 0036841301 scopus 로고    scopus 로고
    • Mice with targeted deletion of eNOS develop hyperdynamic circulation associated with portal hypertension
    • Y. Iwakiri, G. Cadelina, W.C. Sessa, and R.J. Groszmann Mice with targeted deletion of eNOS develop hyperdynamic circulation associated with portal hypertension Am. J. Physiol. 283 2002 G1074 G1081
    • (2002) Am. J. Physiol. , vol.283
    • Iwakiri, Y.1    Cadelina, G.2    Sessa, W.C.3    Groszmann, R.J.4
  • 25
    • 0023638034 scopus 로고
    • Mechanical, morphological and pharmacological properties of oesophageal varices and small mesenteric veins in portal hypertensive rabbits
    • L.S. Jensen, C.O. Juhl, and M.J. Mulvany Mechanical, morphological and pharmacological properties of oesophageal varices and small mesenteric veins in portal hypertensive rabbits Acta Physiol. Scand. 130 1987 649 656
    • (1987) Acta Physiol. Scand. , vol.130 , pp. 649-656
    • Jensen, L.S.1    Juhl, C.O.2    Mulvany, M.J.3
  • 28
    • 0034536291 scopus 로고    scopus 로고
    • Adventitial-derived nitric oxide in rat aortas exposed to endotoxin: Cell origin and functional consequences
    • A.L. Kleschyov, B. Muller, T. Keravis, M.E. Stoeckel, and J.C. Stoclet Adventitial-derived nitric oxide in rat aortas exposed to endotoxin: cell origin and functional consequences Am. J. Physiol. 279 2000 H2743 H2751
    • (2000) Am. J. Physiol. , vol.279
    • Kleschyov, A.L.1    Muller, B.2    Keravis, T.3    Stoeckel, M.E.4    Stoclet, J.C.5
  • 29
    • 0023688960 scopus 로고
    • Nitric oxide, ACh and electrical properties of canine arterial smooth muscle
    • K. Komori, R.R. Lorenz, and P.M. Vanhoutte Nitric oxide, ACh and electrical properties of canine arterial smooth muscle Am. J. Physiol. 255 1988 H207 H212
    • (1988) Am. J. Physiol. , vol.255
    • Komori, K.1    Lorenz, R.R.2    Vanhoutte, P.M.3
  • 30
    • 0022592152 scopus 로고
    • Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor
    • W. Martin, R.F. Furchgott, G.M. Villani, and D. Jothianandan Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor J. Pharmacol. Exp. Ther. 237 1986 529 538
    • (1986) J. Pharmacol. Exp. Ther. , vol.237 , pp. 529-538
    • Martin, W.1    Furchgott, R.F.2    Villani, G.M.3    Jothianandan, D.4
  • 31
    • 0032551891 scopus 로고    scopus 로고
    • Nitric oxide as a mediator of hemodynamic abnormalities and sodium and water retention in cirrhosis
    • P.Y. Martin, P. Gines, and R.W. Schrier Nitric oxide as a mediator of hemodynamic abnormalities and sodium and water retention in cirrhosis N. Engl. J. Med. 339 1998 533 541
    • (1998) N. Engl. J. Med. , vol.339 , pp. 533-541
    • Martin, P.Y.1    Gines, P.2    Schrier, R.W.3
  • 32
    • 0029154015 scopus 로고
    • The role of increased nitric oxide in the vascular hyporeactivity to noradrenaline in long-term portal vein ligated rats
    • P.P. Michielsen, G.E. Boeckxstaens, S.U. Sys, A.G. Herman, and P.A. Pelckmans The role of increased nitric oxide in the vascular hyporeactivity to noradrenaline in long-term portal vein ligated rats J. Hepatol. 23 1995 341 347
    • (1995) J. Hepatol. , vol.23 , pp. 341-347
    • Michielsen, P.P.1    Boeckxstaens, G.E.2    Sys, S.U.3    Herman, A.G.4    Pelckmans, P.A.5
  • 33
    • 0018045665 scopus 로고
    • Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin
    • S. Moncada, and J.R. Vane Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin Pharmacol. Rev. 30 1979 293 331
    • (1979) Pharmacol. Rev. , vol.30 , pp. 293-331
    • Moncada, S.1    Vane, J.R.2
  • 34
    • 0018375431 scopus 로고
    • The active tension-length of vascular smooth muscle related to its cellular components
    • M.J. Mulvany, and D.M. Warshaw The active tension-length of vascular smooth muscle related to its cellular components J. Gen. Physiol. 74 1977 85 104
    • (1977) J. Gen. Physiol. , vol.74 , pp. 85-104
    • Mulvany, M.J.1    Warshaw, D.M.2
  • 35
    • 0034283243 scopus 로고    scopus 로고
    • Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy
    • S.H. Nelson, O.S. Steinsland, Y. Wang, C. Yallampalli, Y.L. Dong, and J.M. Sanchez Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy Circ. Res. 87 2000 6 411
    • (2000) Circ. Res. , vol.87 , pp. 6-411
    • Nelson, S.H.1    Steinsland, O.S.2    Wang, Y.3    Yallampalli, C.4    Dong, Y.L.5    Sanchez, J.M.6
  • 36
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • R.M.J. Palmer, A.G. Ferrige, and S. Moncada Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor Nature 327 1987 524 526
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 37
    • 0025210027 scopus 로고
    • Decreased systemic vascular sensitivity to norepinephrine in portal hypertensive rats: Role of hyperglucagonism
    • M.P. Pizcueta, R. Casamitjana, J. Bosch, and J. Rodes Decreased systemic vascular sensitivity to norepinephrine in portal hypertensive rats: role of hyperglucagonism Am J. Physiol. 258 1990 G191 G195
    • (1990) Am J. Physiol. , vol.258
    • Pizcueta, M.P.1    Casamitjana, R.2    Bosch, J.3    Rodes, J.4
  • 38
    • 0026504731 scopus 로고
    • Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic circulation of rats with portal hypertension
    • M.P. Pizcueta, J.M. Pique, J. Bosch, B.R.J. Whittle, and S. Moncada Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic circulation of rats with portal hypertension Br. J. Pharmacol. 105 1992 184 190
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 184-190
    • Pizcueta, M.P.1    Pique, J.M.2    Bosch, J.3    Whittle, B.R.J.4    Moncada, S.5
  • 39
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • D.D. Rees, R.M.J. Palmer, R. Schulz, H.F. Hodson, and S. Moncada Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo Br. J. Pharmacol. 101 1990 746 752
    • (1990) Br. J. Pharmacol. , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.J.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 40
    • 0034465937 scopus 로고    scopus 로고
    • Pulmonary expression of iNOS and HO-1 protein is upregulated in a rat model of prehepatic portal hypertension
    • R.A. Schroeder, C.A. Ewing, J.V. Sitzmann, and P.C. Kuo Pulmonary expression of iNOS and HO-1 protein is upregulated in a rat model of prehepatic portal hypertension Dig. Dis. Sci. 45 2000 2405 2410
    • (2000) Dig. Dis. Sci. , vol.45 , pp. 2405-2410
    • Schroeder, R.A.1    Ewing, C.A.2    Sitzmann, J.V.3    Kuo, P.C.4
  • 42
    • 0026749847 scopus 로고
    • Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats
    • C.C. Sieber, and R.J. Groszmann Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats Gastroenterology 103 1992 235 239
    • (1992) Gastroenterology , vol.103 , pp. 235-239
    • Sieber, C.C.1    Groszmann, R.J.2
  • 43
    • 18844475814 scopus 로고
    • Evolution of portal hypertension and mechanisms involved in its maintenance in a rat model
    • E. Sikuler, D. Kravetz, and R.J. Grosszmann Evolution of portal hypertension and mechanisms involved in its maintenance in a rat model Am. J. Physiol. 248 1985 G618 G625
    • (1985) Am. J. Physiol. , vol.248
    • Sikuler, E.1    Kravetz, D.2    Grosszmann, R.J.3
  • 44
    • 0023785420 scopus 로고
    • Endothelium-derived hyperpolarising factor, a new endogenous inhibitor from the vascular endothelium
    • S.G. Taylor, and A. Weston Endothelium-derived hyperpolarising factor, a new endogenous inhibitor from the vascular endothelium Trends Pharmacol. Sci. 9 1988 272 274
    • (1988) Trends Pharmacol. Sci. , vol.9 , pp. 272-274
    • Taylor, S.G.1    Weston, A.2
  • 46
    • 0242490247 scopus 로고    scopus 로고
    • Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats
    • M.H. Tsai, Y. Iwakiri, G. Cadelina, W.C. Sessa, and R.J. Groszmann Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats Gastroenterology 125 2003 1452 1461
    • (2003) Gastroenterology , vol.125 , pp. 1452-1461
    • Tsai, M.H.1    Iwakiri, Y.2    Cadelina, G.3    Sessa, W.C.4    Groszmann, R.J.5
  • 47
    • 0025972590 scopus 로고
    • Hyperdynamic circulation in cirrhosis: A role for nitric oxide?
    • P. Vallance, and S. Moncada Hyperdynamic circulation in cirrhosis: a role for nitric oxide? Lancet 337 1991 776 778
    • (1991) Lancet , vol.337 , pp. 776-778
    • Vallance, P.1    Moncada, S.2
  • 48
    • 0029334713 scopus 로고
    • The endothelial and non-endothelial mechanisms responsible for attenuated vasoconstriction in cirrhotic rats
    • L. Van Obbergh, V. Leonard, H. Chen, D. Xu, and G. Blaise The endothelial and non-endothelial mechanisms responsible for attenuated vasoconstriction in cirrhotic rats Exp. Physiol. 80 1995 609 617
    • (1995) Exp. Physiol. , vol.80 , pp. 609-617
    • Van Obbergh, L.1    Leonard, V.2    Chen, H.3    Xu, D.4    Blaise, G.5
  • 49
    • 0036199335 scopus 로고    scopus 로고
    • Modulation of contraction by alpha2A/D-adrenoceptors in mouse aorta: Evidence employing knockout technology
    • C. Vandeputte, and J.R. Docherty Modulation of contraction by alpha2A/D-adrenoceptors in mouse aorta: evidence employing knockout technology Br. J. Pharmacol. 135 2002 1209 1212
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 1209-1212
    • Vandeputte, C.1    Docherty, J.R.2
  • 51
    • 0024893245 scopus 로고
    • Effect of dietary sodium intake on the pressor reactivity to angiotensin II in rats with experimental cirrhosis of the liver
    • L.M. Villamediana, A.L. Garcia-Villalon, C. Caramelo, and J.M. Lopez-Novoa Effect of dietary sodium intake on the pressor reactivity to angiotensin II in rats with experimental cirrhosis of the liver Can. J. Physiol. Pharm. 67 1989 1506 1511
    • (1989) Can. J. Physiol. Pharm. , vol.67 , pp. 1506-1511
    • Villamediana, L.M.1    Garcia-Villalon, A.L.2    Caramelo, C.3    Lopez-Novoa, J.M.4
  • 52
    • 0032701197 scopus 로고    scopus 로고
    • Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase
    • G.J. Waldron, H. Ding, F.P. Lovren, P. Kubes, and C.R. Triggle Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase Br. J. Pharmacol. 128 1999 653 658
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 653-658
    • Waldron, G.J.1    Ding, H.2    Lovren, F.P.3    Kubes, P.4    Triggle, C.R.5
  • 53
    • 0028829108 scopus 로고
    • Endothelium-dependent vascular hyporesponsiveness without detection of nitric oxide synthase induction in aortas of cirrhotic rats
    • A.L. Weigert, P.Y. Martin, M. Niederberger, E.M.S. Higa, I.F. McMurtry, P. Gines, and R.W. Schrier Endothelium-dependent vascular hyporesponsiveness without detection of nitric oxide synthase induction in aortas of cirrhotic rats Hepatology 22 1995 1856 1862
    • (1995) Hepatology , vol.22 , pp. 1856-1862
    • Weigert, A.L.1    Martin, P.Y.2    Niederberger, M.3    Higa, E.M.S.4    McMurtry, I.F.5    Gines, P.6    Schrier, R.W.7
  • 54
    • 0035919476 scopus 로고    scopus 로고
    • Characterization of alpha1-adrenoceptor-mediated contraction in the mouse thoracic aorta
    • Y. Yamamoto, and K. Koike Characterization of alpha1-adrenoceptor- mediated contraction in the mouse thoracic aorta Eur. J. Pharmacol. 424 2001 131 140
    • (2001) Eur. J. Pharmacol. , vol.424 , pp. 131-140
    • Yamamoto, Y.1    Koike, K.2
  • 55
    • 0026684052 scopus 로고
    • Effects of endothelin in portal hypertensive rats
    • P.-C. Yu, J.-S. Kuo, H.-C. Lin, and M.C.M. Yang Effects of endothelin in portal hypertensive rats Clin. Sci. 83 1992 165 170
    • (1992) Clin. Sci. , vol.83 , pp. 165-170
    • Yu, P.-C.1    Kuo, J.-S.2    Lin, H.-C.3    Yang, M.C.M.4


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