Counteraction of axonal growth inhibitory properties of Semaphorin 3A and myelin-associated proteins by a synthetic neurotrophic compound

Journal of Neurochemistry

Volumn 90, Issue 6, 2004, Pages 1423-1431

  Hanbali, Mazen ^a   Bernard, Frédéric ^a   Berton, Caroline ^a   Gatineau, Gilles ^a   Perraut, Martine ^a   Aunis, Dominique ^a   Luu, Bang ^a   Bagnard, Dominique ^a  

^a CENTRE DE NEUROCHIMIE   (France)

Author keywords

Axon; Cortex; Myelin; Neurotrophic factor; Regeneration; Semaphorin

Indexed keywords

3 (15 HYDROXYPENTADECYL) 2,4,4 TRIMETHYLCYCLOHEXEN 2 ONE; ALKANOL; GLIAL SCAR ASSOCIATED INHIBITORY FACTOR; ICFA 15; MYELIN ASSOCIATED GLYCOPROTEIN; NEUROTROPHIC FACTOR; RETINOL; SEMAPHORIN 3A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; EMBRYO; FETUS; GENE OVEREXPRESSION; GLIA CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUSE; NERVE CELL GROWTH; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; SCAR;

ANIMALS; ANIMALS, NEWBORN; AXONS; BLOTTING, WESTERN; CELL COUNT; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOHEXANONES; DENDRITES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; FATTY ALCOHOLS; IMMUNOHISTOCHEMISTRY; MICE; MYELIN-ASSOCIATED GLYCOPROTEIN; NERVE GROWTH FACTORS; NEURITES; NEURONS; SEMAPHORIN-3A; SIGNAL TRANSDUCTION;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 4544295126     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02601.x     Document Type: Article

References (49)

1. Adams R. H., Lohrum M., Klostermann A., Betz H. and Puschel A. W. (1997) The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing. EMBO J. 16, 6077-6086.
2. Alessi D. R., Cuenda A., Cohen P., Dudley D. T. and Saltiel A. R. (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
3. Andersen S. S. and Bi G. Q. (2000) Axon formation: a molecular model for the generation of neuronal polarity. Bioessays 22, 172-179.
4. Bagnard D., Lohrum M., Uziel D., Puschel A. W. and Bolz J. (1998) Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections. Development 125, 5043-5053.
5. Bagnard D., Thomasset N., Lohrum M., Puschel A. W. and Bolz J. (2000) Spatial distributions of guidance molecules regulate chemorepulsion and chemoattraction of growth cones. J. Neurosci. 20, 1030-1035.
6. Bagnard D., Chounlamountri N., Puschel A. W. and Bolz J. (2001a) Axonal surface molecules act in combination with semaphorin 3a during the establishment of corticothalamic projections. Cereb. Cortex 11, 278-285.
7. Bagnard D., Vaillant C., Khuth S. T., Dufay N., Lohrum M., Puschel A. W., Belin M. F., Bolz J. and Thomasset N. (2001b) Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor. J. Neurosci. 21, 3332-3341.
8. Bain J., McLauchlan H., Elliott M. and Cohen P. (2003) The specificities of protein kinase inhibitors: an update. Biochem. J. 371, 199-204.
9. Bradbury E. J., Moon L. D., Popat R. J., King V. R., Bennett G. S., Patel P. N., Fawcett J. W. and McMahon S. B. (2002) Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 416, 636-640.
10. Cai D., Shen Y., De Bellard M., Tang S. and Filbin M. T. (1999) Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism. Neuron 22, 89-101.
11. Cai D., Qiu J., Cao Z., McAtee M., Bregman B. S. and Filbin M. T. (2001) Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate. J. Neurosci. 21, 4731-4739.
12. Campbell D. S. and Holt C. E. (2003) Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones. Neuron 37, 939-952.
13. Condic M. L. (2002) Neural development: axon regeneration derailed by dendrites. Curr. Biol. 12, R455-R457.
14. Davies S. P., Reddy H., Caivano M. and Cohen P (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105.
15. Desai C. J., Sun Q. and Zinn K. (1997) Tyrosine phosphorylation and axon guidance: of mice and flies. Curr. Opin. Neurobiol. 7, 70-74.
16. De Winter F., Holtmaat A. J. and Verhaagen J. (2002) Neuropilin and class 3 semaphorins in nervous system regeneration. Adv. Exp. Med. Biol. 515, 115-139.
17. Eickholt B. J., Walsh F. S. and Doherty P. (2002) An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signalling. J. Cell Biol. 157, 211-217.
18. Engelman J. A., Lisanti M. P. and Scherer P. E. (1998) Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J. Biol. Chem. 273, 32c111-32120.
19. Fouad K., Dietz V. and Schwab M. E. (2001) Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors. Brain Res. Brain Res. Rev. 36, 204-212.
20. Fournier A. E. and Strittmatter S. M. (2001) Repulsive factors and axon regeneration in the CNS. Curr. Opin. Neurobiol. 11, 89-94.
21. Fournier A. E., Takizawa B. T. and Strittmatter S. M. (2003) Rho kinase inhibition enhances axonal regeneration in the injured CNS. J. Neurosci. 23, 1416-1423.
22. Gimenez y Ribotta M., Gaviria M., Menet V. and Privat A. (2002) Strategies for regeneration and repair in spinal cord traumatic injury. Prog. Brain Res. 137, 191-212.
23. Girlanda-Junges C., Lutz-Bucher B., Gonzalez de Aguilar J. L., Loeffler J. P. and Luu B. (2000) 3-(15-Hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1- one and its effect on neuropeptide secretion. Bioorg. Med. Chem. Lett. 10, 2537-2539.
24. Gonzalez de Aguilar J. L., Girlanda-Junges C., Coowar D., Duportail G., Loeffler J. P. and Luu B. (2001) Neurotrophic activity of 2,4,4-trimethyl-3-(15- hydroxypentadecyl)-2-cyclohexen-1-one in cultured central nervous system neurons. Brain Res. 920, 65-73.
25. Gurgo R. D., Bedi K. S. and Nurcombe V. (2002) Current concepts in central nervous system regeneration. J. Clin. Neurosci. 9, 613-617.
26. Hall A. (1998) Rho GTPases and the actin cytoskeleton. Science 279, 509-514.
27. Jones D. M., Tucker B. A., Rahimtula M. and Mearow K. M. (2003) The synergistic effects of NGF and IGF-1 on neurite growth in adult sensory neurons: convergence on the PI 3-kinase signaling pathway. J. Neurochem. 86, 1116-1128.
28. Kim J. E., Li S., GrandPre T., Qiu D. and Strittmatter S. M. (2003) Axon regeneration in young adult mice lacking nogo-a/b. Neuron 38, 187-199.
29. Liu Y., Kim D., Himes B. T., Chow S. Y., Schallen T., Murray M., Tessler A. and Fischer I. (1999) Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. J. Neurosci. 19, 4370-4387.
30. McGee A. W. and Strittmatter S. M. (2003) The Nogo-66 receptor: focusing myelin inhibition of axon regeneration. Trends Neurosci. 26, 193-198.
31. Niclou S. P., Franssen E. H., Ehlert E. M., Taniguchi M. and Verhaagen J. (2003) Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth. Mol. Cell Neurosci. 24, 902-912.
32. Nishiyama M., Hoshino A., Tsai L., Henley J. R., Goshima Y., Tessier-Lavigne M., Poo M. M. and Hong K. (2003) Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning. Nature 424, 990-995.
33. Norton W. T. and Poduslo S. E. (1973) Myelination in rat brain: method of myelin isolation. J. Neurochem. 21, 749-757.
34. Pasterkamp R. J. and Verhaagen J. (2001) Emerging roles for semaphorins in neural regeneration. Brain Res. Brain Res. Rev. 35, 36-54.
35. Ramer M. S., Priestley J. V. and McMahon S. B. (2000) Functional regeneration of sensory axons into the adult spinal cord. Nature 403, 312-316.
36. Sasaki Y., Cheng C., Uchida Y et al. (2002) Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron 35, 907-920.
37. Schnell L., Schneider R., Kolbeck R., Barde Y. A. and Schwab M. E. (1994) Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367, 170-173.
38. Schwab M. E. (2002) Repairing the injured spinal cord. Science 295, 1029-1031.
39. Simonen M., Pedersen V., Weinmann O., Schnell L., Buss A., Ledermann B., Christ F., Sansig G., van der Putten H. and Schwab M. E. (2003) Systemic deletion of the myelin-associated outgrowth inhibitor nogo-a improves regenerative and plastic responses after spinal cord injury. Neuron 38, 201-211.
40. Song H. J. and Poo M. M. (1999) Signal transduction underlying growth cone guidance by diffusible factors. Curr. Opin. Neurobiol. 9, 355-363.
41. Tanelian D. L., Barry M. A., Johnston S. A., Le T. and Smith G. M. (1997) Semaphorin III can repulse and inhibit adult sensory afferents in vivo. Nat. Med. 3, 1398-1401.
42. Terman J. R., Mao T., Pasterkamp R. J., Yu H. H. and Kolodkin A. L. (2002) MlCALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion. Cell 109, 887-900.
43. Tuszynski M. H., Murai K., Blesch A., Grill R. and Miller I. (1997) Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord. Cell Transplant 6, 361-368.
44. Vaudry D., Stork P. J., Lazarovici P. and Eiden L. E. (2002) Signaling pathways for PC12 cell differentiation: making the right connections. Science 296, 1648-1649.
45. Watanabe T. and Miyagawa I. (2002) Effects of long-chain fatty alcohol on peripheral nerve conduction and bladder function in diabetic rats. Life Sci. 70, 2215-2224.
46. Woolf C. J. (2003) No nogo. Now where to go? Neuron 38, 153-156.
47. Xie Y. and Longo F. M. (2000) Neurotrophin small-molecule mimetics. Prog. Brain Res. 128, 333-347.
48. Zheng B., Ho C., Li S., Keirstead H., Steward O. and Tessier-Lavigne M. (2003) Lack of enhanced spinal regeneration in nogo-deficient mice. Neuron 38, 213-224.
49. Zuo J., Neubauer D., Graham J., Krekoski C. A., Ferguson T. A. and Muir D. (2002) Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan. Exp. Neurol. 176, 221-228.