Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor

Journal of Neuroscience

Volumn 21, Issue 10, 2001, Pages 3332-3341

  Bagnard, Dominique ^a,d   Vaillant, Catherine ^a   Khuth, Seng Thuon ^a   Dufay, Nathalie ^a   Lohrum, Marion ^b,e   Püschel, Andreas W ^b   Belin, Marie Françoise ^a   Bolz, Jürgen ^c   Thomasset, Nicole ^a  

^a INSERM   (France)

^b MAX PLANCK INSTITUTE FOR BRAIN RESEARCH   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d CENTRE DE NEUROCHIMIE   (France)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Apoptosis; Migration; Neuropilin; Semaphorin; VEGF; VEGFR1

Indexed keywords

ANGIOGENIC FACTOR; NEUROPILIN; PROTEIN TYROSINE KINASE; RECEPTOR; SEMAPHORIN 3A; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

APOPTOSIS; ARTICLE; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIGAND BINDING; NERVE CELL DIFFERENTIATION; NEUROECTODERM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL;

EID: 0035873074     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-10-03332.2001     Document Type: Article

References (67)

1. Regulation of development and differentiation by the extracellular matrix
2. The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing
3. The Rho GTPases have multiple effects on the actin cytoskeleton
4. Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections
5. Spatial distributions of guidance molecules regulate chemorepulsion and chemoattraction of growth cones
6. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
7. Focalized proteolysis: Spatial and temporal regulation of extracellular matrix degradation at the cell surface
8. Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and platelet-activating factor synthesis is Flk-1-dependent
9. How does the extracellular matrix direct gene expression
10. Tissue structure, nuclear organization, and gene expression in normal and malignant breast
11. Reconstructing cortical connections in a dish
12. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
13. Semaphorinneuropilin interactions underlying sympathetic axon responses to class III semaphorins
14. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
15. Chemoattraction and chemorepulsion of olfactory bulb axons by different secreted semaphorins
16. Human primitive neuroectodermal tumor cells behave as multipotent neural precursors in response to FGF2
17. Cholera toxin beta subunit induces the differentiation of human medulloblastoma cell line DEV in a neuronal pathway
18. Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions
19. Localized collapsing cues can steer growth cones without inducing their full collapse
20. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
21. The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1
22. Semaphorin III can induce death in sensory neurons
23. Differentiation of a medulloblastoma cell line towards an astrocytic lineage using the human T lymphotropic retrovirus-1
24. Membrane bound molecules in rat cerebral cortex regulate thalamic innervation
25. Neural crest apoptosis and the establishment of craniofacial pattern: An honorable death
26. Apoptotic pathways: The roads to ruin
27. Characterization of the turning response of dorsal root neurites towards nerve growth factor
28. Signaling vascular morphogenesis and maintenance
29. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
30. Guidance of thalamocortical axons by growth-promoting molecules in developing rat cerebral cortex
31. Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation
32. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells
33. Neuropilin is a semaphorin III receptor
34. Flt-1, a receptor for vascular endothelial growth factor, has transforming and morphogenic potentials
35. The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis
36. Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord
37. Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: Functional competition of collapsin-1 and vascular endothelial growth factor-165
38. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vaculogenesis and angiogenesis
39. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets
40. Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptors
41. Vascular endothelial growth factor (VEGF) and its receptors
42. Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth
43. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
44. Semaphorins: Repulsive guidance molecules show their attractive side
45. Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension
46. Extracellular matrix molecules and their receptors: Functions in neural development
47. A dominant negative receptor for specific secreted semaphorins is generated by deleting an extracellular domain from neuropilin-1
48. Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A
49. Primitive neuroectodermal tumors of the central nervous system
50. Unified nomenclature for the semaphorins/collapsins
51. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
52. Semaphorins as mediators of neuronal apoptosis
53. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
54. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
55. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates
56. The molecular biology of axon guidance
57. Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development
58. In vivo and in vitro models of medulloblastomas and other primitive neuroectodermal brain tumors of childhood
59. Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos
60. Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro
61. Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the neural crest pathway
62. Ectopic c-kit expression affects the fate of melanocyte precursors in Patch mutant embryos
63. Ectopic semaphorin-1a functions as an attractive guidance cue for developing peripheral neurons
64. The guidance molecule semaphorin III is expressed in regions of spinal cord and periphery avoided by growing sensory axons
65. A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1)
66. Flk-1 a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells
67. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival