Effects of endothelin-1 on hepatic stellate cell proliferation, collagen synthesis and secretion, intracellular free calcium concentration

World Journal of Gastroenterology

Volumn 10, Issue 18, 2004, Pages 2697-2700

  Guo, Chuan Yong ^a   Wu, Jian Ye ^a   Wu, Yun Bin ^a   Zhong, Min Zhang ^a   Lu, Han Ming ^b  

^a TONGJI UNIVERSITY   (China)

^b XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; CALCIUM ION; COLLAGEN; ENDOTHELIN 1; FURA 2 ACETOXYMETHYL ESTER; PROLINE; TRIFLURIDINE; VERAPAMIL;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; CELL PROLIFERATION; CELL SUSPENSION; COLLAGEN METABOLISM; COLLAGEN SYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; EXTRACELLULAR FLUID; IN VITRO STUDY; LIVER CELL; LIVER FIBROSIS; MALE; NONHUMAN; PATHOGENESIS; RAT; STATISTICAL SIGNIFICANCE; STELLATE CELL;

EID: 4544290578     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i18.2697     Document Type: Article

References (51)

1. Huang ZG, Zhai WR, Zhang YE, Zhang XR. Study of heteroserum-induced rat liver fibrosis model and its mechanism. World J Gastroenterol 1998; 4: 206-209
2. Kawada N. The hepatic perisinusoidal stellate cell. Histol Histopathol 1997; 12: 1069-1080
3. Schuppan D, Porov Y. Hepatic fibrosis: From bench to bedside. J Gastroenterol Hepatol 2002; 17(Suppl 3): S300-S305
4. Marra F, Pinzani M. Role of hepatic stellate cells in the pathogenesis of portal hypertension. Nefrologia 2002; 22(Suppl 5): 34-40
5. Mann DA, Smart DE. Transcriptional regulation of hepatic stellate cell activation. Gut 2002; 50: 891-896
6. Ramadori G, SaileB. Mesenchymal cells in the liver-one cell type or two? Liver 2002; 22: 283-294
7. Hasegawa T, Kimura T, Sasaki T, Okada A. Plasma endothelin-1 level as a marker reflecting the severity of portal hypertension in biliary atresia. J Pediatr Surg 2001; 36: 1609-1612
8. Tsuchiya Y, Suzuki S, Inaba K, Sakaguchi T, Baba S, Miwa M, Konno H, Nakamura S. Impact of endothelin-1 on microcirculatory disturbance after partial hepatectomy under ischemia/reperfusion in thioacetamide-induced cirrhotic rats. J Surg Res 2003; 111: 100-108
9. Hasselblatt M, Bunte M, Dringen R, Tabernero A, Medina JM, Giaume C, Siren AL, Ehrenreich H. Effect of endothelin-1 on astrocytic protein content. Glia 2003; 42: 390-397
10. Raue F. Epidemiology of medullary thyroid carcinoma. Recent Results Cancer Res 1992; 125: 47-54
11. Raue F, Zink A. Measurement of free cytosolic calcium in single cells: method and application. Methods Find Exp Clin Pharmacol 1992; 14: 327-332
12. Lyall V, Alam RI, Phan TH, Phan DQ, Heck GL, DeSimone JA. Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+). J Neurophysiol 2002; 87: 399-408
13. Satin LS, Kinard TA. Neurotransmitters and their receptors in the islets of Langerhans of the pancreas: what messages do acetylcholine, glutamate, and GABA transmit? Endocrine 1998; 8: 213-223
14. Brouwer A, Barelds RJ, de Leeuw AM, Blauw E, Plas A, Yap SH, van den Broek AM, Knook DL. Isolation and culture of Kupffer cells from human liver. Ultrastructure, endocytosis and prostaglandin synthesis. J Hepatol 1988; 6: 36-49
15. Hendriks HF, Brouwer A, Knock DL. The role of hepatic fat-storing (stellate) cells in retinoid metabolism. Hepatology 1987; 7: 1368-1371
16. de Leeuw AM, McCarthy SP, Geerts A, Knook DL. Purified rat liver fat-storing cells in culture divide and contain collagen. Hepatology 1984; 4: 392-403
17. Knook DL, Seffelaar AM, de Leeuw AM. Fat-storing cells of the rat liver. Their isolation and pilrification. Exp Cell Res 1982; 139: 468-471
18. Housset C, Rockey DC, Bissell DM. Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1. Proc Natl Acad Sci U S A 1993; 90: 9266-9270
19. Yokomori H, Oda M, Yasogawa Y, Nishi Y, Ogi M, Takahashi M, Ishii H. Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver. Liver 2001; 21: 114-122
20. Moore K, Wendon J, Frazer M, Karani J, Williams R, Badr K. Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. N Engl J Med 1992; 327: 1774-1778
21. Serradeil-Le Gal C, Jouneaux C, Sanchez-Bueno A, Raufaste D, Roche B, Preaux AM, Maffrand JP, Cobbold PH, Hanoune J, Lotersztajn S. Endothelin action in rat liver. Receptors, free Ca2+ oscillations, and activation of glycogenolysis. J Clin Invest 1991; 87: 133-138
22. Moller S, Emmeluth C, Henriksen JH. Elevated circulating plasma endothelin-1 concentrations in cirrhosis. J Hepatol 1993; 19: 285-290
23. Salo J, Francitorra A, Follo A, Navasa M, Gines A, Jimenez W, Gines P, Arroyo V, Rivera F, Rodes J. Increased plasma endothelin in cirrhosis. Relationship with systemic endotoxemia and response to changes in effective blood volume. J Hepatol 1995; 22: 389-398
24. Yokomori H, Oda M, Yasogawa Y, Nishi Y, Ishii H. Signal detection of endothelin receptor subtypes in human cirrhotic liver by a new in situ hybridization method. Med Electron Microsc 2000; 33: 207-216
25. Yokomori H, Oda M, Ogi M, Yoshimura K, Nomura M, Fujimaki K, Kamegaya Y, Tsukada N, Ishii H. Endothelin-1 suppresses plasma membrane Ca++-ATPase, concomitant with contraction of hepatic sinusoidal endothelial fenestrae. Am J Pathol 2003; 162: 557-566
26. Oda M, Han JY, Yokomori H. Local regulators of hepatic sinusoidal microcirculation: recent advances. Clin Hemorheol Microcirc 2000; 23: 85-94
27. Gasull X, Bataller R, Gines P, Sancho-Bru P, Nicolas JM, Gorbig MN, Ferrer E, Badia E, Gual A, Arroyo V, Rodes J. Human myofibroblastic hepatic stellate cells express Ca(2+)-activated K(+) channels that modulate the effects of endothelin-1 and nitric oxide. J Hepatol 2001; 35: 739-748
28. Reinehr RM, Kubitz R, Peters-Regehr T, Bode JG, Haussinger D. Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin 1. Hepatology 1998; 28: 1566-1577
29. Shao R, Rockey DC. Effects of endothelins on hepatic stellate cell synthesis of endothelin-1 during hepatic wound healing. J Cell Physiol 2002; 191: 342-350
30. Kriebel ME, Keller B. The unitary evoked potential at the frog nerve-muscle junction results from synchronous gating of fusion pores at docked vesicles. Cell Biol Int 1999; 23: 527-532
31. Smogorzewski MJ. Central nervous dysfunction in uremia. Am J Kidney Dis 2001; 38(4 Suppl 1): S122-128
32. Satin LS. Localized calcium influx in pancreatic beta-cells: its significance for Ca2+-dependent insulin secretion from the islets of Langerhans. Endocrine 2000; 13: 251-262
33. Murthy KS, Zhou H. Selective phosphorylation of the IP3R-I in vivo by cGMP-dependent protein kinase in smooth muscle. Am J Physiol Gastrointest Liver Physiol 2003; 284: G221-230
34. Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci U S A 1989; 86: 2863-2867
35. Xu D, Emoto N, Giaid A, Slaughter C, Kaw S, deWit D, Yanagisawa M. ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 1994; 78: 473-485
36. Clozel M, Gray GA, Breu V, Loffler BM, Osterwalder R. The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo. Biochem Biophys Res Commun 1992; 186: 867-873
37. Sakurai T, Yanagiasawa M, Masaki T. Molecular characterization of endothelin receptors. Trends Pharmacol Sci 1992; 13: 103-108
38. Higuchi H, Satoh T. Endothelin-1 induces vasoconstriction and nitric oxide release via endothelin ET(B) receptors in isolated perfused rat liver. Eur J Pharmacol 1997; 328: 175-182
39. Jouneaux C, Mallat A, Serradeil-Le Gal C, Goldsmith P, Hanoune J, Lotersztajn S. Coupling of endothelin B receptors to the calcium pump and phospholipase C via Gs and Gq in rat liver. J Biol Chem 1994; 269: 1845-1851
40. Kuddus RH, Nalesnik MA, Subbotin VM, Rao AS, Gandhi CR. Enhanced synthesis and reduced metabolism of endothelin-1 (ET-1) by hepatocytes-an important mechanism of increased endogenous levels of ET-1 in liver cirrhosis. J Hepatol 2000; 33: 725-732
41. Leivas A, Jimenez W, Bruix J, Boix L, Bosch J, Arroyo V, Rivera F, Rodes J. Gene expression of endothelin-1 and ET(A) and ET (B) receptors in human cirrhosis: relationship with hepatic hemodynamics. J Vasc Res 1998; 35: 186-193
42. Gerbes AL, Moller S, Gulberg V, Henriksen JH. Endothelin-1 and -3 plasma concentrations in patients with cirrhosis: role of splanchnic and renal passage and liver function. Hepatology 1995; 21: 735-739
43. Uchihara M, Izumi N, Sato C, Marumo F. Clinical significance of elevated plasma endothelin concentration in patients with cirrhosis. Hepatology 1992; 16: 95-99
44. Asbert M, Gines A, Gines P, Jimenez W, Claria J, Salo J, Arroyo V, Rivera F, Rodes J. Circulating levels of endothelin in cirrhosis. Gastroenterology 1993; 104: 1485-1491
45. Matsumoto H, Uemasu J, Kitano M, Kawasaki H. Clinical significance of plasma endothelin-1 in patients with chronic liver disease. Dig Dis Sci 1994; 39: 2665-2670
46. Moller S, Gulberg V, Henriksen JH, Gerbes AL. Endothelin-1 and endothelin-3 in cirrhosis: relations to systemic and splanchnic haemodynamics. J Hepatol 1995; 23: 135-144
47. Tsai YT, Lin HC, Yang MC, Lee FY, Hou MC, Chen LS, Lee SD. Plasma endothelin levels in patients with cirrhosis and their relationships to the severity of cirrhosis and renal function. J Hepatol 1995; 23: 681-688
48. Martinet JP, Legault L, Cernacek P, Roy L, Dufresne MP, Spahr L, Fenyves D, Pomier-Layrargues G. Changes in plasma endothelin-1 and Big endothelin-1 induced by transjugular intrahepatic portosystemic shunts in patients with cirrhosis and refractory ascites. J Hepatol 1996; 25: 700-706
49. Bernardi M, Gulberg V, Colantoni A, Trevisani F, Gasbarrini A, Gerbes AL. Plasma endothelin-1 and -3 in cirrhosis: relationship with systemic hemodynamics, renal function and neurohumoral. systems. J Hepatol 1996; 24: 161-168
50. Nagasue N, Dhar DK, Yamanoi A, Emi Y, Udagawa J, Yamamoto A, Tachibana M, Kubota H, Kohno H, Harada T. Production and release of endothelin-1 from the gut and spleen in portal hypertension due to cirrhosis. Hepatology 2000; 31: 1107-1114
51. Rieder H, Ramadori G, Meyer zum Buschenfelde KH. Sinusoidal endothelial liver cells in vitro release endothelin: augmentation by transforming growth factor [beta] and Kupffer cell-conditioned media. Klin Wochenschr 1991; 69: 387-391