Duality of innate stress responses in cardiac injury, repair, and remodeling

Journal of Molecular and Cellular Cardiology

Volumn 37, Issue 4, 2004, Pages 801-811

  Wilson, Eric M ^a   Diwan, Abhinav ^b   Spinale, Francis G ^a   Mann, Douglas L ^b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Medical Center   (United States)

Author keywords

Cardiac injury; Innate stress response; Myocardium

Indexed keywords

CARDIOTROPHIN 1; CILIARY NEUROTROPHIC FACTOR; CYTOKINE; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 11; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; MANGANESE SUPEROXIDE DISMUTASE; ONCOSTATIN M; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR;

CARDIOPULMONARY BYPASS; DNA DETERMINATION; DNA SYNTHESIS; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; GRAFT REJECTION; HEART FAILURE; HEART INFARCTION; HEART INJURY; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART STRESS; HEART VENTRICLE HYPERTROPHY; HEMODYNAMICS; HOMEOSTASIS; HYPERTENSION; HYPERTROPHIC CARDIOMYOPATHY; IMMUNE RESPONSE; MAGNESIUM DEFICIENCY; MYOCARDITIS; NICK END LABELING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REPERFUSION INJURY; REVIEW; SARCOMERE; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; VIRUS MYOCARDITIS;

ANIMALS; HEART; HEART DISEASES; HUMANS; IMMUNITY, NATURAL; INFLAMMATION MEDIATORS; MICE; MYOCARDIUM; REGENERATION; STRESS;

EID: 4544265332     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.05.028     Document Type: Review

References (74)

1. Mann DL. Stress-activated cytokines and the heart: from adaptation to maladaptation. Annu Rev Physiol 3 A.D.;65:81-101.
2. Kapadia S., Lee J.R., Torre-Amione G., Birdsall H.H., Ma T.S., Mann D.L. Tumor necrosis factor gene and protein expression in adult feline myocardium after endotoxin administration. J Clin Invest. 96:1995;1042-1052
3. Kapadia S., Oral H., Lee J., Nakano M., Taffet G.E., Mann D.L. Hemodynamic regulation of tumor necrosis factor-α gene and protein expression in adult feline myocardium. Circ Res. 81:1997;187-195
4. Hoffmann J.A., Kafatos F.C., Janeway C.A. Jr, Ezekowitz R.A. Phylogenetic perspectives in innate immunity. Science. 284:(5418):1999;1313-1318
5. Eddy L.J., Goeddel D.V., Wong G.H.W. Tumor necrosis factor-α pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun. 184:1992;1056-1059
6. Nelson S.K., Wong G.H.W., McCord J.M. Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury. J Mol Cell Cardiol. 27:1995;223-229
7. Brown J.M., White C.W., Terada L.S., Grosso M.A., Shanley P.F., Mulvin D.W., et al. Interleukin 1 pretreatment decreases ischemia/reperfusion injury. Proc Natl Acad Sci USA. 87:1990;5026-5030
8. Maulik N., Engelman R.M., Wei Z.J., Lu D., Rousou J.A., Das D.K. Interleukin-1 alpha preconditioning reduces myocardial ischemia reperfusion injury. Circulation. 88:1993;387-394
9. Nakano M., Knowlton A.A., Dibbs Z., Mann D.L. Tumor necrosis factor-α confers resistance to injury induced by hypoxic injury in the adult mammalian cardiac myocyte. Circulation. 97:1998;1392-1400
10. Wong G.H.W., Goeddel D.V. Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism. Science. 242:1988;941-944
11. Nakano M., Knowlton A.A., Yokoyama T., Lesslauer W., Mann D.L. Tumor necrosis factor-α induced expression of heat shock protein 72 in adult feline cardiac myocytes. Am J Physiol. 270:1996;H1231-H1239
12. Low-Friedrich I., Weisensee D., Mitrou P., Schoeppe W. Cytokines induce stress protein formation in cultured cardiac myocytes. Basic Res Cardiol. 87:(1):1992;12-18
13. Marber M.S., Mestril R., Chi S.H., Sayen R., Yellon D.M., Dillmann W.H. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest. 95:1995;1446-1456
14. Plumier J.C.L., Ross B.M., Currie R.W., Angelides C.E., Kazlaris H., Kollias G., et al. Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery. J Clin Invest. 95:1995;1854-1860
15. Narula J., Pandey P., Arbustini E., Haider N., Narula N., Kolodgie F.D., et al. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci USA. 96:(14):1999;8144-8149
16. Erl W., Hansson G.K., de Martin R., Draude G., Weber K.S., Weber C. Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells. Circ Res. 84:(6):1999;668-677
17. Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S.J. NF-kappa B antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 281:(5383):1998;1680-1683
18. Stehlik C., de Martin R., Binder B.R., Lipp J. Cytokine induced expression of porcine inhibitor of apoptosis protein (iap) family member is regulated by NF-kappa B. Biochem Biophys Res Commun. 243:(3):1998;827-832
19. Lee J.P., Palfrey H.C., Bindokas V.P., Ghadge G.D., Ma L., Miller R.J., et al. The role of immunophilins in mutant superoxide dismutase-1linked familial amyotrophic lateral sclerosis. Proc Natl Acad Sci USA. 96:(6):1999;3251-3256
20. Sheng Z., Knowlton K., Chen J., Hoshijima M., Brown J.H., Chien K.R. Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. J Biol Chem. 272:1997;5783-5791
21. Fujio Y., Kunisada K., Hirota H., Yamauchi-Takihara K., Kishimoto T. Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes. J Clin Invest. 99:1997;2898-2905
22. Wang F., Seta Y., Baumgarten G., Engel D.J., Sivasubramanian N., Mann D.L. Functional significance of hemodynamic overload-induced expression of leukemia-inhibitory factor in the adult mammalian heart. Circulation. 103:(9):2001;1296-1302
23. Hirota H., Chen J., Betz U.A., Rajewsky K., Gu Y., Ross J.J., et al. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. 97:(2):1999;189-198
24. Kurrelmeyer K., Michael L., Baumgarten G., Taffet G., Peschon J., Sivasubramanian N., et al. Endogenous myocardial tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci USA. 290:2000;5456-5461
25. Rothe M., Sarma V., Dixit V.M., Goeddel D.V. TRAF2-mediated activation of NF-kB by TNF receptor 2 and CD40. Science. 269:1995;1424-1427
26. Yokoyama T., Nakano M., Bednarczyk J.L., McIntyre B.W., Entman M.L., Mann D.L. Tumor necrosis factor-α provokes a hypertrophic growth response in adult cardiac myocytes. Circulation. 95:1997;1247-1252
27. Bozkurt B., Kribbs S., Clubb F.J. Jr, Michael L.H., Didenko V.V., Hornsby P.J., et al. Pathophysiologically relevant concentrations of tumor necrosis factor-α promote progressive left ventricular dysfunction and remodeling in rats. Circulation. 97:1998;1382-1391
28. Mann D.L. Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res. 91:(11):2002;988-998
29. Kubota T., McTiernan C.F., Frye C.S., Slawson S.E., Koretsky A.P., Demetris A.J., et al. Dilated cardiomyopathy in transgenic mice with cardiac specific overexpression of tumor necrosis factor-alpha. Circ Res. 81:1997;627-635
30. Thaik C.M., Calderone A., Takahashi N., Colucci W.S. Interleukin-1β modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest. 96:1995;1093-1099
31. Krown K.A., Page M.T., Nguyen C., Zechner D., Gutierrez V., Comstock K.L., et al. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes: involvement of the sphingolipid signaling cascade in cardiac cell death. J Clin Invest. 98:1996;2854-2865
32. Pagani F.D., Baker L.S., Hsi C., Knox M., Fink M.P., Visner M.S. Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-α in conscious dogs. J Clin Invest. 90:1992;389-398
33. Bryant D., Becker L., Richardson J., Shelton J., Franco F., Pechock R.M., et al. Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-α (TNF). Circulation. 97:1998;1375-1381
34. Palmer J.N., Hartogensis W.E., Patten M., Fortuin F.D., Long C.S. Interleukin-1β induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest. 95:1995;2555-2564
35. Nakamura K., Fushimi K., Kouchi H., Mihara K., Miyazaki M., Ohe T., et al. Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. Circulation. 98:(8):1998;794-799
36. Sekiguchi K., Li X., Coker M.L., Flesch M., Barger P.M., Sivasubramanian N., et al. Cross-regulation between the renin-angiotensin system and inflammatory mediators in cardiac hypertrophy and failure. Cardiovasc Res. 2004;. [in press]
37. Flesch M., Hoper A., Dell'Italia L., Evans K., Bond R., Peshock R., et al. Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 108:(5):2003;598-604
38. Hirota H., Yoshida K., Kishimoto T., Taga T. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA. 92:1995;4862-4866
39. Arstall M.A., Sawyer D.B., Fukazawa R., Kelly R.A. Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation [see comments]. Circ Res. 85:(9):1999;829-840
40. O'Brien N.W., Gellings N.M., Guo M., Barlow S.B., Glembotski C.C., Sabbadini R.A. Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death. Circ Res. 92:(6):2003;589-591
41. Oral H., Dorn G.W. II, Mann D.L. Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-α in the adult mammalian cardiac myocyte. J Biol Chem. 272:1997;4836-4842
42. Adam-Klages S., Adam D., Wiegmann K., Struve S., Kolanus W., Schneider-Mergener J., et al. FAN, a novel WD-repeat protein couples the p55 TNF receptor to neutral sphingomyelinase. Cell. 86:1996;937-947
43. Kolesnick R.N. Sphingomyelin and derivatives as cellular signals. Prog Lipid Res. 30:1991;1-38
44. Jarvis W.D., Kolesnick R.N., Fornari F.A., Traylor R.S., Gewirtz D.A., Grant S. Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc Natl Acad Sci USA. 91:1994;73-77
45. Pushkareva M., Obeid L.M., Hannun Y.A. Ceramide: an endogenous regulator of apoptosis and growth suppression. Immunol Today. 16:1995;294-297
46. Susin S.A., Zamzami N., Castedo M., Daugas E., Wang H.-G., Geley S., et al. The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1CD95- and ceramide-induced apoptosis. J Exp Med. 186:1997;25-37
47. Engel D., Peshock R., Armstrong R.C., Sivasubramanian N., Mann D.L. Cardiac myocyte apoptosis provokes adverse cardiac remodeling in transgenic mice with targeted overexpression of tumor necrosis factor. Am J Physiol-Heart Circ Phy. 2004;. [in press]
48. Pomerantz B.J., Reznikov L.L., Harken A.H., Dinarello C.A. Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta. Proc Natl Acad Sci USA. 98:(5):2001;2871-2876
49. Mann D.L. Cytokines as mediators of disease progression in the failing heart. Hosenpud J.D., Greenberg B.H. Congestive heart failure. 1999;213-232 Lippincott Williams & Wilkins, Philadelphia
50. Gulick T.S., Chung M.K., Pieper S.J., Lange L.G., Schreiner G.F. Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte β-adrenergic responsiveness. Proc Natl Acad Sci USA. 86:1989;6753-6757
51. Balligand J.L., Ungureanu D., Kelly R.A., Kobzik L., Pimental D., Michel T., et al. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest. 91:1993;2314-2319
52. Combes A., Frye C.S., Lemster B.H., Brooks S.S., Watkins S.C., Feldman A.M., et al. Chronic exposure to interleukin 1beta induces a delayed and reversible alteration in excitation-contraction coupling of cultured cardiomyocytes. Pflugers Arch. 445:(2):2002;246-256
53. 2+ transients and adenylate cyclase activity. Am J Physiol. 272:(4 Pt 2):1997;H1937-H1944
54. Pinsky D.J., Cai B., Yang X., Rodriguez C., Sciacca R.R., Cannon P.J. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. J Clin Invest. 95:(2):1995;677-685
55. Simms M.G., Walley K.R. Activated macrophages decrease rat cardiac myocyte contractility: importance of ICAM-1-dependent adhesion. Am J Physiol. 277:(1 Pt 2):1999;H253-H260
56. Weisensee D., Bereiter-Hahn J., Schoeppe W., Low-Friedrich I. Effects of cytokines on the contractility of cultured cardiac myocytes. Int J Immunopharmacol. 15:(5):1993;581-587
57. Hosenpud J.D. The effects of interleukin-1 on myocardial function and metabolism. Clin Immunol Immunopathol. 68:1993;175-180
58. Schulz R., Panas D.L., Catena R., Moncada S., Olley P.M., Lopaschuk G.D. The role of nitric oxide in cardiac depression induced by interleukin-1β and tumour necrosis factor-α Br J Pharmacol. 114:1995;27-34
59. Dinarello C.A. Interleukin-18. Methods. 19:(1):1999;121-132
60. Yu X., Kennedy R.H., Liu S.J. JAK2/STAT3, not ERK1/2, mediates interleukin-6-induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes. J Biol Chem. 278:(18):2003;16304-16309
61. Franco F., Thomas G.D., Giroir B.P., Bryant D., Bullock M.C., Chwialkowski M.C., et al. Magnetic resonance imaging and invasive evaluation of development of heart failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Circulation. 99:(3):1999;448-454
62. Sivasubramanian N., Coker M.L., Kurrelmeyer K., DeMayo F., Spinale F.G., Mann D.L. Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 2001:(104):2001;826-831
63. Szalai G., Sakata Y., Nemoto S., Sivasubramanian N., Mann D.L. The role of inflammatory mediators in cardiac remodeling. Greenberg B.H. Myocardial remodeling: mechanisms and treatment. 2004;Marcel Dekker, Inc, New York City
64. Siwik D.A., Chang D.L., Colucci W.S. Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro. Circ Res. 86:(12):2000;1259-1265
65. Peng J., Gurantz D., Tran V., Cowling R.T., Greenberg B.H. Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis. Circ Res. 91:(12):2002;1119-1126
66. Felgner P.L., Ringold G.M. Cationic liposome-mediated transfection. Nature. 337:1989;387-388
67. Tsuruda T., Jougasaki M., Boerrigter G., Huntley B.K., Chen H.H., D'Assoro A.B., et al. Cardiotrophin-1 stimulation of cardiac fibroblast growth: roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor. Circ Res. 90:(2):2002;128-134
68. Wang F., Trial J., Diwan A., Gao F., Birdsall H., Entman M., et al. Regulation of cardiac fibroblast cellular function by leukemia inhibitory factor. J Mol Cell Cardiol. 34:(10):2002;1309
69. Li Y.Y., Feng Y.Q., Kadokami T., McTiernan C.F., Draviam R., Watkins S.C., et al. Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy. Proc Natl Acad Sci USA. 97:(23):2000;12746-12751
70. Weber K.T. Cardiac intersitium in health and disease: the fibrillar collagen network. J Am Coll Cardiol. 13:(7):1989;1637-1652
71. Gurantz D., Cowling R.T., Villarreal F.J., Greenberg B.H. Tumor necrosis factor-alpha upregulates angiotensin II type 1 receptors on cardiac fibroblasts. Circ Res. 85:(3):1999;272-279
72. Gray M.O., Long C.S., Kalinyak J.E., Li H.T., Karliner J.S. Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblasts. Cardiovasc Res. 40:(2):1998;352-363
73. Schultz J.J., Witt S.A., Glascock B.J., Nieman M.L., Reiser P.J., Nix S.L., et al. TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II. J Clin Invest. 109:(6):2002;787-796
74. Diwan A., Dibbs Z., Nemoto S., DeFreitas G., Carabello B.A., Sivasubramanian N., et al. Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes. Circulation. 109:(2):2004;262-268