Functional significance of hemodynamic overload-induced expression of leukemia-inhibitory factor in the adult mammalian heart

Circulation

Volumn 103, Issue 9, 2001, Pages 1296-1302

  Wang, Feng ^a,b   Seta, Yukihiro ^a   Baumgarten, Georg ^a   Engel, David J ^a   Sivasubramanian, Natarajan ^a   Mann, Douglas L ^a,b  

^a MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cytokines; Hemodynamics; Inhibitors; Myocytes

Indexed keywords

CARDIOTROPHIN 1; CYTOKINE; GLYCOPROTEIN GP 130; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; CAT; CELL DAMAGE; CELL MOTION; CELL PROTECTION; CONTROLLED STUDY; GENE OVEREXPRESSION; HEART HEMODYNAMICS; HEART MUSCLE CELL; HEMODYNAMIC MONITORING; HOMEOSTASIS; HYPOXIA; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SARCOMERE; STRESS;

EID: 0035814949     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.103.9.1296     Document Type: Article

References (20)

1. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
2. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
3. Cardiotrophin-1 activates a distinct form of cardiac muscle celt hypertrophy
4. Leukemia inhibitory factor induces a hypertrophic response mediated by gp130 in murine cardiac myocytes
5. Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes
6. Leukemia inhibitory factor (LIF) and LIF receptor expression in human endometrium suggests a potential autocrine/paracrine function in regulating embryo implantation
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8. Blocking the endogenous increase in HSP 72 increases susceptibility to hypoxia and reoxygenation in isolated adult feline cardiocytes
9. Biotin-labeled haripin oligonucleotides: Probes to detect double-strand breaks in DNA apoptotic cells
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12. A synthetic inhibitor of the mitogen-activated protein kinase cascade
13. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway
14. Negative inotropic effects of cytokines on the heart mediated by nitric oxide
15. Leukemia inhibitory factor, a potent cardiac hypertrophic cytokine, activates the JAK/STAT pathway in rat cardiomyocytes
16. Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury
17. Molecular signals for initiating protein synthesis in organ hypertrophy
18. Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions
19. Tissue expression and immunolocalization of tumor necrosis factor-α in postinfarction dysfunctional myocardium
20. Cytokine mRNA expression in postischemic/reperfused myocardium