-
1
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
Selkoe DJ. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 1999; 399: A23-A31.
-
(1999)
Nature
, vol.399
-
-
Selkoe, D.J.1
-
3
-
-
4544298529
-
-
Hanir I, Fiser A, Yashida M eds., Plenum Press, London
-
Schröeder H, Lobron C, Wevers A, Maelick A, Giacobini E. In Alzheimer's and Parkinson's Disease: Recent Advances, Hanir I, Fiser A, Yashida M eds., Plenum Press, London 1995.
-
(1995)
Alzheimer's and Parkinson's Disease: Recent Advances
-
-
Schröeder, H.1
Lobron, C.2
Wevers, A.3
Maelick, A.4
Giacobini, E.5
-
4
-
-
0033846277
-
Central nicotinic receptors, neurotrophic factor and neuroprotection
-
Belluardo N, Mudo G, Blum, M, Fuxe K. Central nicotinic receptors, neurotrophic factor and neuroprotection. Behav Brain Res 2000; 113: 21-34.
-
(2000)
Behav. Brain Res.
, vol.113
, pp. 21-34
-
-
Belluardo, N.1
Mudo, G.2
Blum, M.3
Fuxe, K.4
-
5
-
-
0029899143
-
In vitro neuroprotective properties of the novel cholinergic channels activator (ChCA), ABT-418
-
Donnely-Roberts DL, Xue IC, Arneric SP, Sullivan JP. In vitro neuroprotective properties of the novel cholinergic channels activator (ChCA), ABT-418. Brain Res 1996; 719: 36-44.
-
(1996)
Brain Res.
, vol.719
, pp. 36-44
-
-
Donnely-Roberts, D.L.1
Xue, I.C.2
Arneric, S.P.3
Sullivan, J.P.4
-
6
-
-
0030564986
-
Nicotine rescues PC12 cells from death induced by nerve growth factor deprivation
-
Yamashita H, Nakamura S. Nicotine rescues PC12 cells from death induced by nerve growth factor deprivation. Neurosci Lett 1996; 213: 145-147.
-
(1996)
Neurosci. Lett.
, vol.213
, pp. 145-147
-
-
Yamashita, H.1
Nakamura, S.2
-
7
-
-
0031975130
-
Nicotinic α 7 receptors protect against glutamate neurotoxicity and neuronal ischaemic damage
-
Shimohama S, Greenwald DL, Shafron DH, Akaika A, Maeda T, et al. Nicotinic α 7 receptors protect against glutamate neurotoxicity and neuronal ischaemic damage. Brain Res 1998; 779: 359-363.
-
(1998)
Brain Res.
, vol.779
, pp. 359-363
-
-
Shimohama, S.1
Greenwald, D.L.2
Shafron, D.H.3
Akaika, A.4
Maeda, T.5
-
8
-
-
0034006944
-
β-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
-
Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB. β-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem 2000; 275: 5626-5632.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5626-5632
-
-
Wang, H.Y.1
Lee, D.H.2
D'Andrea, M.R.3
Peterson, P.A.4
Shank, R.P.5
Reitz, A.B.6
-
9
-
-
0033846169
-
Nicotinic treatment for degenerative and neuropsyquiatric disorders such as Alzheimer's disease and Parkinson's disease
-
Rusted JM, Newhouse PA, Levin ED. Nicotinic treatment for degenerative and neuropsyquiatric disorders such as Alzheimer's disease and Parkinson's disease. Behav Brain Res 2000; 113: 121-129.
-
(2000)
Behav. Brain Res.
, vol.113
, pp. 121-129
-
-
Rusted, J.M.1
Newhouse, P.A.2
Levin, E.D.3
-
10
-
-
0028890920
-
Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology
-
Perry EK, Morris CM, Court JA, Cheng A, Fairbairn AF, McKeith IG, et al. Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology. Neurosci 1995; 64: 385-395.
-
(1995)
Neurosci.
, vol.64
, pp. 385-395
-
-
Perry, E.K.1
Morris, C.M.2
Court, J.A.3
Cheng, A.4
Fairbairn, A.F.5
McKeith, I.G.6
-
11
-
-
0028916581
-
Kinetic analysis of regional (S)(-)11C-nicotine binding in normal and Alzheimer brains - In vivo assessment using positron emission tomography
-
Nordberg A, Lundqvist H, Hartvig P, Lilja A, Langstrom B. Kinetic analysis of regional (S)(-)11C-nicotine binding in normal and Alzheimer brains - in vivo assessment using positron emission tomography. Alzheimer Dis Assoc Disord 1995; 9: 21-27.
-
(1995)
Alzheimer Dis. Assoc. Disord.
, vol.9
, pp. 21-27
-
-
Nordberg, A.1
Lundqvist, H.2
Hartvig, P.3
Lilja, A.4
Langstrom, B.5
-
12
-
-
0027370152
-
In vivo detection of neurotransmitter changes in Alzheimer's disease
-
Nordberg A. In vivo detection of neurotransmitter changes in Alzheimer's disease. Ann NY Acad Sci 1993; 695: 27-33.
-
(1993)
Ann. NY Acad. Sci.
, vol.695
, pp. 27-33
-
-
Nordberg, A.1
-
13
-
-
0027399410
-
Relationship between cigarette smoking and Alzheimer's disease in a population-based case-control study
-
Brenner DE, Kukull WA, Van Belle G, Bowen JD, McCormick WC, Teri L, et al. Relationship between cigarette smoking and Alzheimer's disease in a population-based case-control study. Neurology 1993; 43: 293-300.
-
(1993)
Neurology
, vol.43
, pp. 293-300
-
-
Brenner, D.E.1
Kukull, W.A.2
Van Belle, G.3
Bowen, J.D.4
McCormick, W.C.5
Teri, L.6
-
15
-
-
0025644484
-
Cholinergic receptors in human brain: Effects of aging and Alzheimer's disease
-
Giacobini E. Cholinergic receptors in human brain: effects of aging and Alzheimer's disease. J Neurosci Res 1990; 27: 548-560.
-
(1990)
J. Neurosci. Res.
, vol.27
, pp. 548-560
-
-
Giacobini, E.1
-
16
-
-
0029013373
-
Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex
-
Summers KL, Giacobini E. Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex. Neurochem Res 1995; 20: 753-759.
-
(1995)
Neurochem. Res.
, vol.20
, pp. 753-759
-
-
Summers, K.L.1
Giacobini, E.2
-
17
-
-
0030827671
-
Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via α7-neuronal receptors and neuronal CNS receptors
-
Kaneko S, Maeda T, Kume T, Kochiyama H, Akaike A, Shimohama S, et al. Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via α7-neuronal receptors and neuronal CNS receptors. Brain Res 1997; 765: 135-140.
-
(1997)
Brain Res.
, vol.765
, pp. 135-140
-
-
Kaneko, S.1
Maeda, T.2
Kume, T.3
Kochiyama, H.4
Akaike, A.5
Shimohama, S.6
-
18
-
-
0242694942
-
Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation
-
Stevens TR, Krueger SR, Fitzsimonds RM, Picciotto MR. Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation. Neurosci. 2003; 23: 10093-10099.
-
(2003)
Neurosci.
, vol.23
, pp. 10093-10099
-
-
Stevens, T.R.1
Krueger, S.R.2
Fitzsimonds, R.M.3
Picciotto, M.R.4
-
19
-
-
0023951465
-
Intravenous nicotine in Alzheimer's disease: A pilot study
-
Newhouse PA, Sunderland T, Tariot PN, Blumbardt CL, Weingartner H, Mellow A, et al. Intravenous nicotine in Alzheimer's disease: a pilot study. Psychopharmacology 1988; 95: 171-175.
-
(1988)
Psychopharmacology
, vol.95
, pp. 171-175
-
-
Newhouse, P.A.1
Sunderland, T.2
Tariot, P.N.3
Blumbardt, C.L.4
Weingartner, H.5
Mellow, A.6
-
20
-
-
0024385514
-
The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type
-
Sahakian B, Jones G, Levy R, Gray J, Warburton D. The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type. Br J Psychiatry 1989; 154: 797-800.
-
(1989)
Br. J. Psychiatry
, vol.154
, pp. 797-800
-
-
Sahakian, B.1
Jones, G.2
Levy, R.3
Gray, J.4
Warburton, D.5
-
21
-
-
0028287659
-
Age-related effects of the nicotinic antagonist mecamylamine on cognition and behaviour
-
Newhouse PA, Potter A, Corwin J, Lenox R. Age-related effects of the nicotinic antagonist mecamylamine on cognition and behaviour. Neuropsychopharmacology 1994; 10: 93-107.
-
(1994)
Neuropsychopharmacology
, vol.10
, pp. 93-107
-
-
Newhouse, P.A.1
Potter, A.2
Corwin, J.3
Lenox, R.4
-
22
-
-
0028883095
-
Diversity of neuronal nicotinic acetylcholine receptors: Lessons from behaviour and implications for CNS therapeutics
-
Decker Mw, Brioni Jd, Bannon Aw, Arneric Sp. Diversity of neuronal nicotinic acetylcholine receptors: lessons from behaviour and implications for CNS therapeutics. Life Sci 1995; 56: 545-70.
-
(1995)
Life Sci.
, vol.56
, pp. 545-570
-
-
Decker, M.W.1
Brioni, J.D.2
Bannon, A.W.3
Arneric, S.P.4
-
23
-
-
0025898437
-
Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease
-
Schroder H, Giacobini E, Struble RG, Zilles K, Maelicke A. Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease. Neurobiol Aging 1991; 12: 259-262.
-
(1991)
Neurobiol. Aging
, vol.12
, pp. 259-262
-
-
Schroder, H.1
Giacobini, E.2
Struble, R.G.3
Zilles, K.4
Maelicke, A.5
-
24
-
-
0026386753
-
Dementia: The neurochemical basis of putative transmitter orientated therapy
-
Court JA, Perry EK. Dementia: the neurochemical basis of putative transmitter orientated therapy. Pharmacol Ther 1991; 52: 423-443.
-
(1991)
Pharmacol. Ther.
, vol.52
, pp. 423-443
-
-
Court, J.A.1
Perry, E.K.2
-
25
-
-
0027031286
-
Neuroreceptor changes in Alzheimer disease
-
Nordberg A. Neuroreceptor changes in Alzheimer disease. Cerebrovasc Brain Metab Rev 1992; 4: 303-328.
-
(1992)
Cerebrovasc. Brain Metab. Rev.
, vol.4
, pp. 303-328
-
-
Nordberg, A.1
-
26
-
-
0032454039
-
Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease
-
Mattson M, Pedersen WA. Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease. Int J Devl Neurosci 1998; 16: 737-753.
-
(1998)
Int. J. Devl. Neurosci.
, vol.16
, pp. 737-753
-
-
Mattson, M.1
Pedersen, W.A.2
-
27
-
-
0034194089
-
Calcium signalling in the ER: Its role in neuronal plasticity and neurodegenerative disorders
-
Mattson M, Laferla FM, Chan SL, Leissring MA, Shepel PN, Geiger JD. Calcium signalling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci 2000; 23: 222-229.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 222-229
-
-
Mattson, M.1
Laferla, F.M.2
Chan, S.L.3
Leissring, M.A.4
Shepel, P.N.5
Geiger, J.D.6
-
28
-
-
0032127927
-
Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families
-
Etcheberrigaray R, Hirashima N, Nee L, Prince J, Govoni S, Racchi M, et al. Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families. Neurobiol Dis 1998; 5: 37-45.
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 37-45
-
-
Etcheberrigaray, R.1
Hirashima, N.2
Nee, L.3
Prince, J.4
Govoni, S.5
Racchi, M.6
-
29
-
-
0035147432
-
Dependence of vital cell function on endoplasmic reticulum calcium levels: Implications for the mechanisms underlying neuronal cell injury in different pathological states
-
Paschen W. Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states. Cell Calcium 2001; 29: 1-11.
-
(2001)
Cell Calcium
, vol.29
, pp. 1-11
-
-
Paschen, W.1
-
30
-
-
0031776912
-
Bcl-2 protects against apoptosis in neuronal cell line caused by thapsigargin-induced depletion of intracellular calcium stores
-
Wei H, Wei W, Bredesen DE, Perry DC. Bcl-2 protects against apoptosis in neuronal cell line caused by thapsigargin-induced depletion of intracellular calcium stores. Neurochem 1998; 70: 2305-2314.
-
(1998)
Neurochem.
, vol.70
, pp. 2305-2314
-
-
Wei, H.1
Wei, W.2
Bredesen, D.E.3
Perry, D.C.4
-
31
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, et al. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol 1999; 1: 479-485.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
-
32
-
-
0030567769
-
Calcium homeostasis in aged neurons
-
Kirischuk S, Verkhratsky A. Calcium homeostasis in aged neurons. Life Sci 1996; 59: 451-459.
-
(1996)
Life Sci.
, vol.59
, pp. 451-459
-
-
Kirischuk, S.1
Verkhratsky, A.2
-
33
-
-
0028204224
-
Calcium ionophore increases amyloid beta peptide production by cultured cells
-
Querfurth HW, Selkoe DJ. Calcium ionophore increases amyloid beta peptide production by cultured cells. Biochemistry 1994; 33: 4550-4561.
-
(1994)
Biochemistry
, vol.33
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
34
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides
-
Hartmann T, Bieger SC, Bruhl B, Tienari PJ, Ida N, Allsop D, et al. Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides. Nat Med 1997; 3: 1016-1020.
-
(1997)
Nat. Med.
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
-
35
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localisation to intracellular membranes in mammalian cells
-
Kovacs DM, Fausett HJ, Page KJ, Kim TW, Moir RD, Merriam DE, et al. Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localisation to intracellular membranes in mammalian cells. Nat Med 1996; 2: 224-229.
-
(1996)
Nat. Med.
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
Kim, T.W.4
Moir, R.D.5
Merriam, D.E.6
-
36
-
-
0028980748
-
Alzheimer amyloid beta-peptides exhibit ionophore-like properties in human erythrocytes
-
Engstrom I, Ronquist G, Pettersson L, Waldenstrom A. Alzheimer amyloid beta-peptides exhibit ionophore-like properties in human erythrocytes. Eur J Clin Invest 1995; 25: 471-476.
-
(1995)
Eur. J. Clin. Invest.
, vol.25
, pp. 471-476
-
-
Engstrom, I.1
Ronquist, G.2
Pettersson, L.3
Waldenstrom, A.4
-
37
-
-
0029586704
-
Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity
-
Pollard HB, Arispe N, Rojas E. Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity. Cell Mol Neurobiol 1995; 15: 513-526.
-
(1995)
Cell Mol. Neurobiol.
, vol.15
, pp. 513-526
-
-
Pollard, H.B.1
Arispe, N.2
Rojas, E.3
-
38
-
-
0022899577
-
Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type
-
Summers WK, Majovski LV, Marsh GM, Tachiki K, Kling A. Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type. N Engl J Med 1986; 315: 1241-1245.
-
(1986)
N. Engl. J. Med.
, vol.315
, pp. 1241-1245
-
-
Summers, W.K.1
Majovski, L.V.2
Marsh, G.M.3
Tachiki, K.4
Kling, A.5
-
39
-
-
0027526076
-
Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: Assessment of attentional and mnemonic function using CANTAB
-
Sahakian BJ, Owen AM, Morant NJ, Eagger SA, Boddington S, Crayton L, et al. Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: assessment of attentional and mnemonic function using CANTAB. Psychopharmacology (Berl) 1993; 110: 395-401.
-
(1993)
Psychopharmacology (Berl.)
, vol.110
, pp. 395-401
-
-
Sahakian, B.J.1
Owen, A.M.2
Morant, N.J.3
Eagger, S.A.4
Boddington, S.5
Crayton, L.6
-
40
-
-
0028316959
-
Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease
-
Watkins PB, Zimmerman HJ, Knapp MJ, Gracon SI, Lewis KW. Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease. JAMA 1994; 271: 992-998.
-
(1994)
JAMA
, vol.271
, pp. 992-998
-
-
Watkins, P.B.1
Zimmerman, H.J.2
Knapp, M.J.3
Gracon, S.I.4
Lewis, K.W.5
-
42
-
-
0033668050
-
Galanthamine: A review of its use in Alzheimer's disease
-
Scott LJ, Goa KL. Galanthamine: a review of its use in Alzheimer's disease. Drugs 2000; 60: 1095-1122.
-
(2000)
Drugs
, vol.60
, pp. 1095-1122
-
-
Scott, L.J.1
Goa, K.L.2
-
43
-
-
0027429837
-
Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease
-
Enz A, Amstutz R, Boddeke H, Gmelin G, Malanowski J. Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease. Prog Brain Res 1993; 98: 431-438.
-
(1993)
Prog. Brain Res.
, vol.98
, pp. 431-438
-
-
Enz, A.1
Amstutz, R.2
Boddeke, H.3
Gmelin, G.4
Malanowski, J.5
-
44
-
-
0035163347
-
Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
-
Dovey HE, John V, Anderson JP, Chen LZ, De Saint Andrieu P, Fang LY, et al. Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. J Neurochem 2001; 76: 173-181.
-
(2001)
J. Neurochem.
, vol.76
, pp. 173-181
-
-
Dovey, H.E.1
John, V.2
Anderson, J.P.3
Chen, L.Z.4
De Saint Andrieu, P.5
Fang, L.Y.6
-
45
-
-
0028918426
-
Cholinesterase inhibitors increase secretion of APPs in rat brain cortex
-
Mori F, Lai CC, Fusi F, Giacobini E. Cholinesterase inhibitors increase secretion of APPs in rat brain cortex. Neuroreport 1995; 6: 633-636.
-
(1995)
Neuroreport
, vol.6
, pp. 633-636
-
-
Mori, F.1
Lai, C.C.2
Fusi, F.3
Giacobini, E.4
-
46
-
-
0035123732
-
Do cholinesterase inhibitors have disease-modifying effects in Alzheimer's disease?
-
Giacobini E. Do cholinesterase inhibitors have disease-modifying effects in Alzheimer's disease? CNS Drugs 2001; 15: 85-91.
-
(2001)
CNS Drugs
, vol.15
, pp. 85-91
-
-
Giacobini, E.1
-
47
-
-
0029821586
-
A preliminary open trial with nimodipine in patients with cognitive impairment and leukoaraiosis
-
Pantoni L, Carosi M, Amigoni S, Mascalchi M, Inzitari D. A preliminary open trial with nimodipine in patients with cognitive impairment and leukoaraiosis. Clin Neuropharmacol 1996; 19: 497-506.
-
(1996)
Clin. Neuropharmacol.
, vol.19
, pp. 497-506
-
-
Pantoni, L.1
Carosi, M.2
Amigoni, S.3
Mascalchi, M.4
Inzitari, D.5
-
48
-
-
0033059445
-
Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and β-amyloid pathologies
-
Kelliher M, Fastbom J, Cowburn RF, Bonkale W, Ohm TG, Ravid R, et al. Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and β-amyloid pathologies. Neuroscience 1999; 92: 499-513.
-
(1999)
Neuroscience
, vol.92
, pp. 499-513
-
-
Kelliher, M.1
Fastbom, J.2
Cowburn, R.F.3
Bonkale, W.4
Ohm, T.G.5
Ravid, R.6
-
49
-
-
0030915855
-
Oxidative stress hypothesis in Alzheimer's disease
-
Markesbery WR. Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 1997; 23: 134-147.
-
(1997)
Free Radic. Biol. Med.
, vol.23
, pp. 134-147
-
-
Markesbery, W.R.1
-
51
-
-
0012213056
-
Clinical and preclinical information of anti-oxidants: Idebenone and vitamin E
-
Thal L J. Clinical and preclinical information of anti-oxidants: Idebenone and vitamin E. Neurobiol Aging 1998; 19: 20.
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 20
-
-
Thal, L.J.1
-
52
-
-
0028085516
-
Estrogen deficiency and risk of Alzheimer's disease in women
-
Paganini-Hill A, Henderson VW. Estrogen deficiency and risk of Alzheimer's disease in women. Am J Epidemiol 1994; 140: 256-261.
-
(1994)
Am. J. Epidemiol.
, vol.140
, pp. 256-261
-
-
Paganini-Hill, A.1
Henderson, V.W.2
-
53
-
-
0031946864
-
Estrogen reduces neuronal generation of Alzheimer amyloid peptides
-
Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, et al. Estrogen reduces neuronal generation of Alzheimer amyloid peptides. Nat Med 1998; 4: 447-451.
-
(1998)
Nat. Med.
, vol.4
, pp. 447-451
-
-
Xu, H.1
Gouras, G.K.2
Greenfield, J.P.3
Vincent, B.4
Naslund, J.5
Mazzarelli, L.6
-
54
-
-
0033968704
-
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease
-
Pappolla MA, Chyan YJ, Poeggeler B, Frangione B, Wilson G, Ghiso J, et al. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease. J Neural Transm 2000; 107: 203-231.
-
(2000)
J. Neural. Transm.
, vol.107
, pp. 203-231
-
-
Pappolla, M.A.1
Chyan, Y.J.2
Poeggeler, B.3
Frangione, B.4
Wilson, G.5
Ghiso, J.6
-
55
-
-
0031022142
-
Janus faces of NF-κB: Neurodestruction versus neuroprotection
-
Lipton SA. Janus faces of NF-κB: neurodestruction versus neuroprotection. Nat Med 1997; 3: 20-22.
-
(1997)
Nat. Med.
, vol.3
, pp. 20-22
-
-
Lipton, S.A.1
-
56
-
-
0034742675
-
Nuclear factor κB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection
-
Lipsky RH, Xu K, Zhu D, Kelly C, Terhakopian A, Novelli A, et al. Nuclear factor κB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection. J Neurochem 2001; 78: 254-264.
-
(2001)
J. Neurochem.
, vol.78
, pp. 254-264
-
-
Lipsky, R.H.1
Xu, K.2
Zhu, D.3
Kelly, C.4
Terhakopian, A.5
Novelli, A.6
-
57
-
-
0029040355
-
In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes
-
Dragunow M, Faull RL, Lawlor P, Beilharz EJ, Singleton K, Walker EB, et al. In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes. Neuroreport 1995; 6: 1053-1057.
-
(1995)
Neuroreport
, vol.6
, pp. 1053-1057
-
-
Dragunow, M.1
Faull, R.L.2
Lawlor, P.3
Beilharz, E.J.4
Singleton, K.5
Walker, E.B.6
-
58
-
-
0029912056
-
Mechanisms of neuronal death in Alzheimer's disease
-
Cotman CW, Su JH. Mechanisms of neuronal death in Alzheimer's disease. Brain Pathol 1996; 6: 493-506.
-
(1996)
Brain Pathol.
, vol.6
, pp. 493-506
-
-
Cotman, C.W.1
Su, J.H.2
-
59
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
60
-
-
0344688198
-
Galanthamine prevents apoptosis induced by β-amyloid and thapsigargin: Involvement of nicotinic acetylcholine receptors
-
Arias E, Ales E, Gabilan NH, Cano-Abad ME, Villarroya M, Garcia AG, et al. Galanthamine prevents apoptosis induced by β -amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology 2004; 46: 103-114.
-
(2004)
Neuropharmacology
, vol.46
, pp. 103-114
-
-
Arias, E.1
Ales, E.2
Gabilan, N.H.3
Cano-Abad, M.E.4
Villarroya, M.5
Garcia, A.G.6
-
61
-
-
0037622682
-
Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons
-
Takada Y, Yonezawa A, Kume T, Katsuki H, Kaneko S, Sugimoto H, et al. Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons. J Pharmacol Exp Ther 2003; 306: 772-777.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 772-777
-
-
Takada, Y.1
Yonezawa, A.2
Kume, T.3
Katsuki, H.4
Kaneko, S.5
Sugimoto, H.6
-
62
-
-
0033729119
-
Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: A model of the membrane defect of Alzheimer's disease
-
Farber SA, Slack BE, Blusztajn JK. Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease. FASEB J 2000; 14: 2198-2206.
-
(2000)
FASEB J.
, vol.14
, pp. 2198-2206
-
-
Farber, S.A.1
Slack, B.E.2
Blusztajn, J.K.3
-
63
-
-
0033403796
-
Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion
-
Alvarez XA, Mouzo R, Pichel V, Perez P, Laredo M, Fernandez-Novoa L, et al. Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion. Methods Find Exp Clin Pharmacol 1999; 21: 633-644.
-
(1999)
Methods Find Exp. Clin. Pharmacol.
, vol.21
, pp. 633-644
-
-
Alvarez, X.A.1
Mouzo, R.2
Pichel, V.3
Perez, P.4
Laredo, M.5
Fernandez-Novoa, L.6
-
64
-
-
0022435132
-
Image reconstruction of the Alzheimer paired helical filament
-
Crowther RA, Wischik CM. Image reconstruction of the Alzheimer paired helical filament. EMBO J 1985; 4: 3661-3665.
-
(1985)
EMBO J.
, vol.4
, pp. 3661-3665
-
-
Crowther, R.A.1
Wischik, C.M.2
-
65
-
-
0034680902
-
Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain
-
Bennecib M, Gong CX, Grundke-Iqbal I, Iqbal K. Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain. FEBS Lett 2000; 485: 87-93,
-
(2000)
FEBS Lett.
, vol.485
, pp. 87-93
-
-
Bennecib, M.1
Gong, C.X.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
66
-
-
0032731763
-
Brain inflammation in Alzheimer disease and the therapeutic implications
-
Mcgeer EG, Mcgeer PL. Brain inflammation in Alzheimer disease and the therapeutic implications. Curr Pharm Des 1999; 5: 821-836.
-
(1999)
Curr. Pharm. Des.
, vol.5
, pp. 821-836
-
-
Mcgeer, E.G.1
Mcgeer, P.L.2
-
68
-
-
0034254924
-
Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease
-
Lim GP, Yang F, Chu T, Chen P, Beech W, Teter B, et al. Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease. J Neurosci 2000; 20: 5709-5714.
-
(2000)
J. Neurosci.
, vol.20
, pp. 5709-5714
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Chen, P.4
Beech, W.5
Teter, B.6
-
69
-
-
0034639568
-
Non-steroidal anti-inflammatory drugs with selectivity for cyclooxygenase-2 in Alzheimer's disease. Rationale and perspectives
-
Blain H, Jouzeau JY, Blain A, Terlain B, Trechot P, Touchon J, et al. Non-steroidal anti-inflammatory drugs with selectivity for cyclooxygenase-2 in Alzheimer's disease. Rationale and perspectives. Presse Med 2000; 29: 267-273,
-
(2000)
Presse Med.
, vol.29
, pp. 267-273
-
-
Blain, H.1
Jouzeau, J.Y.2
Blain, A.3
Terlain, B.4
Trechot, P.5
Touchon, J.6
-
70
-
-
0033615580
-
The presenilins in' Alzheimer's disease- proteolysis holds the key
-
Haass C, De Strooper B. The presenilins in' Alzheimer's disease- proteolysis holds the key. Science 1999; 286: 916-919.
-
(1999)
Science
, vol.286
, pp. 916-919
-
-
Haass, C.1
De Strooper, B.2
-
71
-
-
0024417125
-
Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease
-
Geula C, Mesulam M. Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease. Brain Res 1989; 498: 185-189.
-
(1989)
Brain Res.
, vol.498
, pp. 185-189
-
-
Geula, C.1
Mesulam, M.2
-
72
-
-
0029863697
-
Acety1cholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: Possible role of the peripheral site of the enzyme
-
Inestrosa NC, Alvarez A, Pérez CA, Moreno RD, Vicente M, Linker C, et al. Acety1cholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 1996; 16: 881-891.
-
(1996)
Neuron.
, vol.16
, pp. 881-891
-
-
Inestrosa, N.C.1
Alvarez, A.2
Pérez, C.A.3
Moreno, R.D.4
Vicente, M.5
Linker, C.6
-
73
-
-
0031587286
-
Acetylcholinesterase promotes the aggregation of amyloid β-peptide fragments by forming a complex with the growing fibrils
-
Álvarez A, Opazo C, Alarcón R, Garrido J, Inestrosa NC. Acetylcholinesterase promotes the aggregation of amyloid β-peptide fragments by forming a complex with the growing fibrils. J Mol Biol 1997; 272: 348-361.
-
(1997)
J. Mol. Biol.
, vol.272
, pp. 348-361
-
-
Álvarez, A.1
Opazo, C.2
Alarcón, R.3
Garrido, J.4
Inestrosa, N.C.5
-
74
-
-
0034488989
-
Acetylcholinesterase-amyloid-β-peptide interaction and Wnt signaling involvement in Aβ neurotoxicity
-
Inestrosa NC, Álvarez A, Godoy J, Reyes A, De Ferrari GV. Acetylcholinesterase-amyloid-β-peptide interaction and Wnt signaling involvement in Aβ neurotoxicity. Acta Neurol Scand 2000; 176: 53-59.
-
(2000)
Acta Neurol. Scand.
, vol.176
, pp. 53-59
-
-
Inestrosa, N.C.1
Álvarez, A.2
Godoy, J.3
Reyes, A.4
De Ferrari, G.V.5
-
75
-
-
0037298750
-
β-amyloid aggregation induced by human acetylcholinesterase: Inhibition studies
-
Bartolini M, Bertucci C, Cavrini V, Andrisano V. β-amyloid aggregation induced by human acetylcholinesterase: inhibition studies. Biochem Pharmacol 2003; 65: 407-416.
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 407-416
-
-
Bartolini, M.1
Bertucci, C.2
Cavrini, V.3
Andrisano, V.4
-
76
-
-
0028197477
-
Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines
-
Lahiri DK, Lewis S, Farlow MR. Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines. J Neurosci Res 1994; 37: 777-787.
-
(1994)
J. Neurosci. Res.
, vol.37
, pp. 777-787
-
-
Lahiri, D.K.1
Lewis, S.2
Farlow, M.R.3
-
77
-
-
0032569990
-
The secretion of amyloid β-peptides is inhibited in the tacrine-treated human neuroblastoma cells
-
Lahiri DK, Farlow MR, Sambamurti K. The secretion of amyloid β-peptides is inhibited in the tacrine-treated human neuroblastoma cells. Brain Res Mol 1998; 62: 131-140.
-
(1998)
Brain Res. Mol.
, vol.62
, pp. 131-140
-
-
Lahiri, D.K.1
Farlow, M.R.2
Sambamurti, K.3
-
78
-
-
0035912825
-
Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development
-
Shaw KT, Utsuki T, Rogers J, Yu QS, Sambamurti K, Brossi A. Ge YW, et al. Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development. Proc Natl Acad Sci USA 2001; 98: 7605-7610.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7605-7610
-
-
Shaw, K.T.1
Utsuki, T.2
Rogers, J.3
Yu, Q.S.4
Sambamurti, K.5
Brossi, A.6
Ge, Y.W.7
-
79
-
-
0002216086
-
The structure and multifaceted function of the amyloid precursor protein
-
Boyt AA, Suzuky T, Hone E, Gnjec A, Martins RM. The structure and multifaceted function of the amyloid precursor protein. Clin Biochem Rev 2000; 21: 22-41.
-
(2000)
Clin. Biochem. Rev.
, vol.21
, pp. 22-41
-
-
Boyt, A.A.1
Suzuky, T.2
Hone, E.3
Gnjec, A.4
Martins, R.M.5
-
81
-
-
0036315026
-
Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: Correlation with cognitive benefit
-
Giacobini E, Spiegel R, Enz A, Veroff AE, Cutler NR. Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit. J Neural Transm 2002; 109: 1053-1065.
-
(2002)
J. Neural Transm.
, vol.109
, pp. 1053-1065
-
-
Giacobini, E.1
Spiegel, R.2
Enz, A.3
Veroff, A.E.4
Cutler, N.R.5
-
82
-
-
0025213932
-
Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain
-
Siek GC, Katz LS, Fishman EB, Korosi TS, Marquis JK. Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain. Biol Psychiatry 1990; 27: 573-580.
-
(1990)
Biol. Psychiatry
, vol.27
, pp. 573-580
-
-
Siek, G.C.1
Katz, L.S.2
Fishman, E.B.3
Korosi, T.S.4
Marquis, J.K.5
-
83
-
-
0028709150
-
Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors
-
Weinstock M, Razin M, Chorev M, Enz A. Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors. J Neural Transm Suppl 1994; 43: 219-225.
-
(1994)
J. Neural Transm. Suppl.
, vol.43
, pp. 219-225
-
-
Weinstock, M.1
Razin, M.2
Chorev, M.3
Enz, A.4
-
84
-
-
0033845742
-
Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease
-
Maelicke A, Schrattenholz A, Samochocki M, Radina M, Albuquerque E. Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease. Behav Brain Res 2000; 113: 199-206.
-
(2000)
Behav. Brain Res.
, vol.113
, pp. 199-206
-
-
Maelicke, A.1
Schrattenholz, A.2
Samochocki, M.3
Radina, M.4
Albuquerque, E.5
-
85
-
-
0035105750
-
Synthesis and acetylcholinesterase/butyrylcholinesterase inhibition activity of new tacrine-like analogues
-
Marco J L, De Los Ríos C, Carreiras MDC, Baõs JE, Badía A, Vivas N. Synthesis and acetylcholinesterase/butyrylcholinesterase inhibition activity of new tacrine-like analogues. Bioorg Med Chem 2001; 9 (Suppl. 3): 727-732.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, Issue.SUPPL. 3
, pp. 727-732
-
-
Marco, J.L.1
De Los Ríos, C.2
Carreiras, M.D.C.3
Baõs, J.E.4
Badía, A.5
Vivas, N.6
-
86
-
-
0036009905
-
Novel tacrine derivatives that block neuronal calcium channels
-
De Los Ríos C, Marco J L, Carreiras MDC, Chinchón PM, García AG, Villarroya M. Novel tacrine derivatives that block neuronal calcium channels. Bioorg Med Chem 2002; 10: 2077-2088.
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 2077-2088
-
-
De Los Ríos, C.1
Marco, J.L.2
Carreiras, M.D.C.3
Chinchón, P.M.4
García, A.G.5
Villarroya, M.6
-
87
-
-
0032545384
-
Tacrine and physostigmine block nicotinic receptors in Xenopus oocytes injected with Torpedo electroplaque membranes
-
Canti C, Bodas E, Marsal J, Solsona C. Tacrine and physostigmine block nicotinic receptors in Xenopus oocytes injected with Torpedo electroplaque membranes. Eur J Pharmacol 1998; 363: 197-202.
-
(1998)
Eur. J. Pharmacol.
, vol.363
, pp. 197-202
-
-
Canti, C.1
Bodas, E.2
Marsal, J.3
Solsona, C.4
-
88
-
-
0031565285
-
Distinct effects of ω-toxins and various groups of Ca(2+)-entry inhibitors on nicotinic acetylcholine receptor and Ca2+ channels of chromaffin cells
-
Villarroya M, De La Fuente MT, López MG, Gandía L, Garcia AG. Distinct effects of ω-toxins and various groups of Ca(2+)-entry inhibitors on nicotinic acetylcholine receptor and Ca2+ channels of chromaffin cells. Eur J Pharmacol 1997; 320: 249-57.
-
(1997)
Eur. J. Pharmacol.
, vol.320
, pp. 249-257
-
-
Villarroya, M.1
De La Fuente, M.T.2
López, M.G.3
Gandía, L.4
Garcia, A.G.5
-
89
-
-
0037286233
-
Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): Targets for the development of novel therapeutics against neurodegenerative diseases
-
Campiani G, Fattorusso C, De Angelis M, Catalanotti B, Butini S, Fattorusso R, el al. Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases. Curr Pharm Design 2003; 9(8): 599-625.
-
(2003)
Curr. Pharm. Design
, vol.9
, Issue.8
, pp. 599-625
-
-
Campiani, G.1
Fattorusso, C.2
De Angelis, M.3
Catalanotti, B.4
Butini, S.5
Fattorusso, R.6
-
90
-
-
0041677655
-
A point of view: The need to identify an antigen in psyconeurommumological disorders
-
Covelli V, Pellegrino NM, Jirillo E. A point of view: The need to identify an antigen in psyconeurommumological disorders. Curr Pharm Design 2003; 9(24): 1951-5.
-
(2003)
Curr. Pharm. Design
, vol.9
, Issue.24
, pp. 1951-1955
-
-
Covelli, V.1
Pellegrino, N.M.2
Jirillo, E.3
-
91
-
-
0037242768
-
Peptidases, proteases and amyloid beta-peptide catabolism
-
Hersh LB. Peptidases, proteases and amyloid beta-peptide catabolism. Curr Pharm Design 2003; 9(6): 449-54.
-
(2003)
Curr. Pharm. Design
, vol.9
, Issue.6
, pp. 449-454
-
-
Hersh, L.B.1
|