Identification of a novel human MT5-MMP transcript variant in multipotent NT2 cells

FEBS Letters

Volumn 581, Issue 30, 2007, Pages 5923-5928

  Ross, Heather H ^a,b   Fillmore, Helen L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Cloning; CNS; MMP24; MT5 MMP; NT2; Variant

Indexed keywords

MATRIX METALLOPROTEINASE; MEMBRANE TYPE 5 MATRIX METALLOPROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR CLONING; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS;

ADULT; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; BACTERIA; BASE SEQUENCE; BRAIN; CELL DIFFERENTIATION; CELLS, CULTURED; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; HUMANS; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MULTIPOTENT STEM CELLS; NEURONS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 45249107860     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.11.074     Document Type: Article

References (14)

1. Yong V.W., Krekoski C.A., Forsythe P.A., Bell R., and Edwards D.R. Matrix metalloproteinases and diseases of the CNS. TINS 21 2 (1998) 75-80
2. Lukes A., Mun-Bryce S., Lukes M., and Rosenberg G.A. Extracellular matrix degradation by metalloproteinases and central nervous system diseases. Mol. Neurobiol. 19 3 (1999) 267-284
3. Egeblad M., and Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2 (2002) 161-174
4. Somerville R.P., Oblander S.A., and Apte S.S. Matrix metalloproteinases: old dogs with new tricks. Genome Biol. 4 3 (2003) 216
5. McCawley L., and Matrisian L. Matrix metalloproteinases: they're not just for matrix anymore!. Curr. Opin. Cell Biol. 13 (2001) 534-540
6. Fillmore H.L., Van Meter T., and Broaddus W.C. Membrane-type matrix metalloproteinases (MT-MMPs): expression and function during glioma invasion. J. Neuro-Oncol. 53 (2001) 187-202
7. Jaworski D.M. Developmental regulation of membrane-type 5 matrix metalloproteinase (MT5-MMP) expression in the rat nervous system. Brain Res. 860 (2000) 174-177
8. Pei D. Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP. JBC 274 13 (1999) 8925-8932
9. Sekine-Aizawa Y., Hama E., Watanbe K., Tsubuki S., Kanai-Azuma M., Kanai Y., Arai H., Aizawa H., Iwata N., and Saido T.C. Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum. Eur. J. Neurosci. 13 (2001) 935-948
10. Hayashita-Kinoh H., Kinoh H., Okada A., Komori K., Itoh Y., Chiba T., Kajita M., Yana I., and Seiki M. Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth. Cell Growth Differ. 12 (2001) 573-580
11. Pleasure S.J., Page C., and Lee V.M. Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J. Neurosci. 12 5 (1992) 1802-1815
12. Llano E., Pendas A.M., Freije J.P., Nakano A., Knauper V., Murphy G., and Lopez-Otin C. Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors. Cancer Res. 59 (1999) 2570-2576
13. Tsukatani T., Fillmore H.L., Hamilton H.R., Holbrook E.H., and Costanzo R.M. Matrix metalloproteinase expression in the olfactory epithelium. Neuroreport 14 8 (2003) 1135-1140
14. Kajita M., Kinoh H., Ito N., Takamura A., Itoh Y., Okada A., Sato H., and Seiki M. Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse MT4-MMP transcripts. FEBS Lett. 457 3 (1999) 353-356