Generation of tobacco lines with widely different reduction in nicotine levels via RNA silencing approaches

Journal of Biosciences

Volumn 33, Issue 2, 2008, Pages 177-184

  Wang, Peng ^a   Liang, Zhifeng ^a   Zeng, Jia ^a   Li, Wenchao ^a   Sun, Xiaofen ^a   Miao, Zhiqi ^b   Tang, Kexuan ^a,b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

N methyltransferase; Nicotiana tabacum; Nicotine; Plant breeding; Putrescine RNA interference; RNA silencing

Indexed keywords

COMPLEMENTARY DNA; COMPLEMENTARY RNA; METHYLTRANSFERASE; NICOTINE; PLANT RNA; PUTRESCINE N METHYLTRANSFERASE;

ENZYME ACTIVITY; GENETIC ENGINEERING; RNA; TOBACCO; TRANSGENIC PLANT;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SILENCING; GENETIC LINE; GENETIC VARIABILITY; METABOLITE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT GENETICS; RNA INTERFERENCE; RNA VECTOR; TOBACCO;

BASE SEQUENCE; DNA PRIMERS; METHYLTRANSFERASES; NICOTINE; POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, PLANT; TOBACCO;

NICOTIANA TABACUM;

EID: 45249096289     PISSN: 02505991     EISSN: 02505991     Source Type: Journal    
DOI: 10.1007/s12038-008-0035-6     Document Type: Article

References (35)

1. Allen R S, Millgate A G, Chitty J A, Thisleton J, Miller J A C, Fist A J, Gerlach W L and Larkin P J 2004 RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy; Nat. Biotechnol. 22 1559-1566
2. Baldwin I T 1989 Mechanism of damage-induced alkaloid production in wild tobacco; J. Chem. Ecol. 15 1661-1680
3. Baulcombe D 2004 RNA silencing in plants; Nature (London) 431 356-363
4. Brodersen P and Voinnet O 2006 The diversity of RNA silencing pathways in plants; Trends Genet. 22 268-280
5. Chintapakorn Y and Hamill J D 2003 Antisense-mediated down-regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine; Plant Mol. Biol. 53 87-105
6. Dawson R F 1941 Accumulation of nicotine in reciprocal grafts of tomato and tobacco; Am. J. Bot. 29 66-71
7. Dixon R A 2005 Engineering of plant natural product pathways; Curr. Opin. Plant Biol. 8 329-336
8. Facchini P J 2001 Alkaloid biosynthesis in plants: biochemistry, cell biology, molecular regulation, and metabolic engineering applications; Annu. Rev. Plant Physiol. Plant Mol. Biol. 52 29-66
9. Fiore M C, Bailey W C, Cohen S J, Dorfman S F, Goldstein M G, Gritz E R, Heyman R B, Jaen C R, Kottke T E and Lando H A 2000 Treating tobacco use and dependence: clinical practice guidelines (Rockville, MA, USA: US Department of Health and Human Services, Public Health Service)
10. Giovannoni J J 2006 Breeding new life into plant metabolism; Nat. Biotechnol. 24 418-419
11. Hall J 2005 Application of RNAi in biomedical research; Chimia 59 803-807
12. Hashimoto T and Yamada Y 1994 Alkaloid biogenesis - molecular aspects; Annu. Rev. Plant Physiol. Plant Mol. Biol. 45 257-285
13. Ito M, Kawano K, Miyagishi M and Taira K 2005 Genome-wide application of RNAi to the discovery of potential drug targets; FEBS Lett. 579 5988-5995
14. Jefferson R A, Kavanagh T A and Bevan M A 1987 β-glucuronidase as a sensitive and versatile marker in higher plants; EMBO J. 6 3301-3307
15. Jenuwein T and Allis C D 2001 Translating the histone code; Science 293 1074-1080
16. Jimenez-Ruiz C, Kunze M and Fagerstrom K O 1998 Nicotine replacement: a new approach to reducing tobacco-related harm; Eur. Respir. J. 11 473-479
17. Kidd S K, Melillo A A, Lu R H, Reed D G, Kuno N, Uchida K, Furuya M and Jelesko J G 2006 The A and B loci in tobacco regulate a network of stress response genes, few of which are associated with nicotine biosynthesis; Plant Mol. Biol. 60 699-716
18. Laviolette S R and van der Kooy D 2004 The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour; Nat. Rev. Neurosci. 5 55-65
19. Morandini P and Salamini F 2003 Plant biotechnology and breeding: allied for years to come; Trends Plant Sci. 8 70-75
20. Nakatani H and Malik V S 1992 Putrescine N-methyltransferase, recombinant DNA molecules encoding putrescine N-methyltrasferase, and transgenic tobacco plants with altered nicotine content; European Patent Application Number 91310283.6
21. Nugroho L H and Verpoorte R 2002 Secondary metabolism in tobacco; Plant Cell Tiss. Org. Cult. 68 105-125
22. Ogita S, Uefuji H, Yamaguchi Y, Koizumi N and Sano H 2003 RNA interference - producing decaffeinated coffee plants; Nature (London) 423 823
23. Powledge T M 2004 Nicotine as therapy; PLoS Biol. 2 1707-1710
24. Riechers D E and Timko M P 1999 Structure and expression of the gene family encoding putrescine N-methyltransferase in Nicotiana tabacum: new clues to the evolutionary origin of cultivated tobacco; Plant Mol .Biol. 41 387-401
25. Saitoh F, Noma M and Kawashima N 1985 The alkaloid contents of sixty Nicotiana species; Phytochemistry 24 477-480
26. Sato F, Hashimoto T, Hachiya A, Tamura K, Choi K B, Morishige T, Fujimoto H and Yamada Y 2001 Metabolic engineering of plant alkaloid biosynthesis; Proc. Natl. Acad. Sci. USA 98 367-372
27. Saunders J A and Blume D E 1981 Quantitation of major tobacco alkaloids by high-performance liquid chromatography; J. Chromatogr. 205 147-154
28. Shi Z and Fu L W 2004 RNAi and its application in tumor study; Prog. Biochem. Biophys. 31 492-499
29. Steppuhn A, Gase K, Krock B, Halitschke R and Baldwin I T 2004 Nicotine's defensive function in nature; PLoS Biol. 2 1074-1080
30. Tang G L and Galili G 2004 Using RNAi to improve plant nutritional value: from mechanism to application; Trends Biotechnol. 22 463-469
31. Valleau W D 1949 Breeding low-nicotine tobacco; J. Agric. Res. 78 171-181
32. Vignali M, Hassan A H, Neely K E and Workman J L 2000 ATP-dependent chromatin-remodeling complexes; Mol. Cell. Biol. 20 1899-1910
33. Voelckel C, Krugel T, Gase K, Heidrich N, van Dam N M, Winz R and Baldwin I T 2001 Anti-sense expression of putrescine N-methyltransferase confirms defensive role of nicotine in Nicotiana sylvestris against Manduca sexta; Chemoecology 11 121-126
34. Wang E M and Wagner G J 2003 Elucidation of the functions of genes central to diterpene metabolism in tobacco trichomes using posttranscriptional gene silencing; Planta 216 686-691
35. Wingard S A 1928 Hosts and symptoms of ring spot, a virus disease of plants; J. Agric. Res. 37 127-153