A regulatory code for neuron-specific odor receptor expression

PLoS Biology

Volumn 6, Issue 5, 2008, Pages 1069-1083

  Ray, Anandasankar ^a,b   Van Der Goes Van Naters, Wynand ^a   Carlson, John R ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SCALLOPED; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR POU; DROSOPHILA PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; DROSOPHILA; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ORGANIZATION; NONHUMAN; OLFACTORY RECEPTOR; PHYLOGENY; REGULATORY MECHANISM; REGULATORY SEQUENCE; ANIMAL; BIOLOGICAL MODEL; GENE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; ODOR; OLFACTORY SYSTEM; SEQUENCE ANALYSIS;

ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; GENES, INSECT; MODELS, GENETIC; ODORS; OLFACTORY PATHWAYS; OLFACTORY RECEPTOR NEURONS; RECEPTORS, ODORANT; SEQUENCE ANALYSIS;

EID: 45149130763     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0060125     Document Type: Article

References (42)

1. Dahanukar A, Hallem EA, Carlson JR (2005) Insect chemoreception. Curr Opin Neurobiol 15: 423-430.
2. Hallem EA, Dahanukar A, Carlson JR (2006) Insect odor and taste receptors. Annu Rev Entomol 51: 113-135.
3. Shykind BM, Rohani SC, O'Donnell S, Nemes A, Mendelsohn M, et al. (2004) Gene switching and the stability of odorant receptor gene choice. Cell 117: 801-815.
4. Serizawa S, Miyamichi K, Nakatani H, Suzuki M, Saito M, et al. (2003) Negative feedback regulation ensures the one receptor-one olfactory neuron rule in mouse. Science 302: 2088-2094.
5. Lomvardas S, Barnea G, Pisapia DJ, Mendelsohn M, Kirkland J, et al. (2006) Interchromosomal interactions and olfactory receptor choice. Cell 126: 403-413.
6. Lewcock JW, Reed RR (2004) A feedback mechanism regulates monoallelic odorant receptor expression. Proc Natl Acad Sci U S A 101: 1069-1074.
7. Chess A, Simon I, Cedar H, Axel R (1994) Allelic inactivation regulates olfactory receptor gene expression. Cell 78: 823-834.
8. Gimelbrant A, Hutchinson JN, Thompson BR, Chess A (2007) Widespread monoallelic expression on human autosomes. Science 318: 1136-1140.
9. Fuss SH, Omura M, Mombaerts P (2007) Local and cis effects of the H element on expression of odorant receptor genes in mouse. Cell 130: 373-384.
10. Nishizumi H, Kumasaka K, Inoue N, Nakashima A, Sakano H (2007) Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis. Proc Natl Acad Sci U S A 104: 20067-20072.
11. de Bruyne M, Foster K, Carlson J (2001) Odor coding in the Drosophila antenna. Neuron 30: 537-552.
12. de Bruyne M, Clyne PJ, Carlson JR (1999) Odor coding in a model olfactory organ: the Drosophila maxillary palp. Journal of Neuroscience 19: 4520-4532.
13. Clyne PJ, Warr CG, Freeman MR, Lessing D, Kim JH, et al. (1999) A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila. Neuron 22: 327-338.
14. Vosshall LB, Amrein H, Morozov PS, Rzhetsky A, Axel R (1999) A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96: 725-736.
15. Robertson HM, Warr CG, Carlson JR (2003) Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster. Proc Natl Acad Sci U S A 100 Suppl 2: 14537-14542.
16. Vosshall L, Wong A, Axel R (2000) An olfactory sensory map in the fly brain. Cell 102: 147-159.
17. Clyne P, Grant A, O'Connell R, Carlson JR (1997) Odorant response of individual sensilla on the Drosophila antenna. Invert Neurosci 3: 127-135.
18. Elmore T, Ignell R, Carlson JR, Smith DP (2003) Targeted mutation of a Drosophila odor receptor defines receptor requirement in a novel class of sensillum. J Neurosci 23: 9906-9912.
19. Couto A, Alenius M, Dickson BJ (2005) Molecular, anatomical, and functional organization of the Drosophila olfactory system. Curr Biol 15: 1535-1547.
20. Dobritsa AA, Van der Goes van Naters W, Warr CG, Steinbrecht RA, Carlson JR (2003) Integrating the molecular and cellular basis of odor coding in the Drosophila antenna. Neuron 37: 827-841.
21. Goldman AL, Van der Goes van Naters W, Lessing D, Warr CG, Carlson JR (2005) Coexpression of two functional odor receptors in one neuron. Neuron 45: 661-666.
22. Hallem EA, Ho MG, Carlson JR (2004) The molecular basis of odor coding in the Drosophila antenna. Cell 117: 965-979.
23. Ray A, Van der Goes van Naters W, Shiraiwa T, Carlson JR (2007) Mechanisms of odor receptor gene choice in Drosophila. Neuron 53: 353-369.
24. Bergman CM, Pfeiffer BD, Rincon-Limas DE, Hoskins RA, Gnirke A, et al. (2002) Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome. Genome Biol 3: RESEARCH0086.
25. Komiyama T, Carlson JR, Luo LQ (2004) Olfactory receptor neuron axon targeting: intrinsic transcriptional control and hierarchical interactions. Nat Neurosci 7: 819-825.
26. Halder G, Carroll SB (2001) Binding of the Vestigial co-factor switches the DNA-target selectivity of the Scalloped selector protein. Development 128: 3295-3305.
27. Campbell S, Inamdar M, Rodrigues V, Raghavan V, Palazzolo M, et al. (1992) The scalloped gene encodes a novel, evolutionarily conserved transcription factor required for sensory organ differentiation in Drosophila. Genes Dev 6: 367-379.
28. Shyamala BV, Chopra A. (1999) Drosophila melanogaster chemosensory and muscle development:identification and properties of a novel allele of scalloped and of a new locus, SG18.1, in a Gal4 enhancer trap screen. J Genet 78: 87-97.
29. Garg A, Srivastava A, Davis MM, O'Keefe SL, Chow L, et al. (2007) Antagonizing Scalloped with a novel vestigial construct reveals an important role for Scalloped in Drosophila melanogaster leg, eye and optic lobe development. Genetics 175: 659-669.
30. Kreher SA, Kwon JY, Carlson JR (2005) The molecular basis of odor coding in the Drosophila larva. Neuron 46: 445-456.
31. Fishilevich E, Domingos AI, Asahina K, Naef F, Vosshall LB, et al. (2005) Chemotaxis behavior mediated by single larval olfactory neurons in Drosophila. Curr Biol 15: 2086-2096.
32. Fishilevich E, Vosshall LB (2005) Genetic and functional subdivision of the Drosophila antennal lobe. Curr Biol 15: 1548-1553.
33. Lanjuin A, Sengupta P (2004) Specification of chemosensory neuron subtype identities in Caenorhabditis elegans. Curr Opin Neurobiol 14: 22-30.
34. Hirota J, Omura M, Mombaerts P (2007) Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci 34: 679-688.
35. Kolterud A, Alenius M, Carlsson L, Bohm S (2004) The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity. Development 131: 5319-5326.
36. Clyne PJ, Certel SJ, de Bruyne M, Zaslavsky L, Johnson WA, et al. (1999) The odor specificities of a subset of olfactory receptor neurons are governed by Acj6, a POU-domain transcription factor. Neuron 22: 339-347.
37. Inamdar M, Vijayraghavan K, Rodrigues V (1993) The Drosophila homolog of the human transcription factor TEF-1, scalloped, is essential for normal taste behavior. J Neurogenet 9: 123-139.
38. Endo K, Aoki T, Yoda Y, Kimura K, Hama C (2007) Notch signal organizes the Drosophila olfactory circuitry by diversifying the sensory neuronal lineages. Nat Neurosci 10: 153-160.
39. Feinstein P, Mombaerts P (2004) A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell 117: 817-831.
40. Wang F, Nemes A, Mendelsohn M, Axel R (1998) Odorant receptors govern the formation of a precise topographic map. Cell 93: 47-60.
41. Mombaerts P, Wang F, Dulac C, Chao SK, Nemes A, et al. (1996) Visualizing an olfactory sensory map. Cell 87: 675-686.
42. Sharma Y, Cheung U, Larsen EW, Eberl DF (2002) PPTGAL, a convenient Gal4 P-element vector for testing expression of enhancer fragments in Drosophila. Genesis 34: 115-118.