Role of ADAMs in endothelial cell permeability: Cadherin shedding and leukocyte rolling

Circulation Research

Volumn 102, Issue 10, 2008, Pages 1139-1142

  Ponnuchamy, Bharathy ^a   Khalil, Raouf A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cell adhesion; Disintegrin; Endothelium; Metalloproteinase; Vascular

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE PROTEIN 1; A DISINTEGRIN AND METALLOPROTEASE PROTEIN 10; A DISINTEGRIN AND METALLOPROTEASE PROTEIN 12; A DISINTEGRIN AND METALLOPROTEASE PROTEIN 15; ADAM PROTEIN; DISINTEGRIN; GAMMA SECRETASE; METALLOPROTEINASE; NERVE CELL ADHESION MOLECULE; P CADHERIN; PROTEIN KINASE C; RHO KINASE; SELECTIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULAR ENDOTHELIAL CADHERIN; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN RECEPTOR; CADHERIN;

BLOOD VESSEL WALL; CALCIUM TRANSPORT; CELL ADHESION; CELL INFILTRATION; CELL INTERACTION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL MOTILITY; CELL PROLIFERATION; CELL STRUCTURE; EDITORIAL; ENDOTHELIUM CELL; FUNCTIONAL PROTEOMICS; HUMAN; LEUKOCYTE ROLLING; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR LESION; VASCULITIS; CAPILLARY PERMEABILITY; CYTOLOGY; LEUKOCYTE; NOTE; PHYSIOLOGY;

ADAM PROTEINS; CADHERINS; CAPILLARY PERMEABILITY; ENDOTHELIAL CELLS; HUMANS; LEUKOCYTE ROLLING; LEUKOCYTES;

EID: 45149112724     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.177394     Document Type: Editorial

References (40)

1. Rippe B, Haraldsson B. Transport of macromolecules across micro-vascular walls: the two-pore theory. Physiol Rev. 1994;74:163-219.
2. Lampugnani MG, Resnati M, Raiteri M, Pigott R, Pisacane A, Houen G, Ruco LP, Dejana E. A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J Cell Biol. 1992;118:1511-1522.
3. Packard RR, Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem. 2008;54: 24-38.
4. Hafezi-Moghadam A, Thomas KL, Prorock AJ, Huo Y, Ley K. L-selectin shedding regulates leukocyte recruitment. J Exp Med. 2001;193: 863-872.
5. Rabiet MJ, Plantier JL, Rival Y, Genoux Y, Lampugnani MG, Dejana E. Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization. Arterioscler Thromb Vasc Biol. 1996;16:488-496.
6. Herren B, Levkau B, Raines EW, Ross R. Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Mol Biol Cell. 1998;9:1589-1601.
7. Blankenberg S, Barbaux S, Tiret L. Adhesion molecules and atherosclerosis. Atherosclerosis. 2003;170:191-203.
8. Herren B. ADAM-mediated shedding and adhesion: a vascular perspective. News Physiol Sci. 2002;17:73-76.
9. Moss ML, Lambert MH. Shedding of membrane proteins by ADAM family proteases. Essays Biochem. 2002;38:141-153.
10. Becherer JD, Blobel CP. Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs). Curr Top Dev Biol. 2003;54:101-123.
11. Seals DF, Courtneidge SA. The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes Dev. 2003;17:7-30.
12. Duffy MJ, Lynn DJ, Lloyd AT, O'Shea CM. The ADAMs family of proteins: from basic studies to potential clinical applications. Thromb Haemost. 2003;89:622-631.
13. Trochon V, Li H, Vasse M, Frankenne F, Thomaidis A, Soria J, Lu H, Gardner C, Soria C. Endothelial metalloprotease-disintegrin protein (ADAM) is implicated in angiogenesis in vitro. Angiogenesis. 1998;2: 277-285.
14. Rocks N, Paulissen G, El Hour M, Quesada F, Crahay C, Gueders M, Foidart JM, Noel A, Cataldo D. Emerging roles of ADAM and ADAMTS metalloproteinases in cancer. Biochimie. 2008;90:369-379.
15. Bell JH, Herrera AH, Li Y, Walcheck B. Role of ADAM17 in the ectodomain shedding of TNF-α and its receptors by neutrophils and macrophages. J Leukoc Biol. 2007;82:173-176.
16. Eto K, Puzon-McLaughlin W, Sheppard D, Sehara-Fujisawa A, Zhang XP, Takada Y. RGD-independent binding of integrin α9β 1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction. J Biol Chem. 2000;275:34922-34930.
17. Boulday G, Coupel S, Coulon F, Soulillou JP, Charreau B. Antigraft antibody-mediated expression of metalloproteinases on endothelial cells. Differential expression of TIMP-1 and ADAM-10 depends on antibody specificity and isotype. Circ Res. 2001;88:430-437.
18. Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CLl-mediated cell-cell adhesion. Blood. 2003;102: 1186-1195.
19. Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. J Immunol. 2004;172:3678-3685.
20. 2+ influx and PKC activation. J Cell Biol. 2004;165:893-902.
21. Garton KJ, Gough PJ, Philalay J, Wille PT, Blobel CP, Whitehead RH, Dempsey PJ, Raines EW. Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17). J Biol Chem. 2003;278:37459-37464.
22. Tsakadze NL, Sithu SD, Sen U, English WR, Murphy G, D'Souza SE. Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1). J Biol Chem. 2006;281:3157-3164.
23. Mechtersheimer S, Gutwein P, Agmon-Levin N, Stoeck A, Oleszewski M, Riedle S, Postina R, Fahrenholz F, Fogel M, Lemmon V, Altevogt P. Ectodomain shedding of LI adhesion molecule promotes cell migration by autocrine binding to integrins. J Cell Biol. 2001;155:661-673.
24. Huang AJ, Manning JE, Bandak TM, Ratau MC, Hanser KR, Silverstein SC. Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells. J Cell Biol. 1993; 120:1371-1380.
25. Schulz B, Pruessmeyer J, Maretzky T, Ludwig A, Blobel CP, Saftig P, Reiss K. ADAM 10 regulates endothelial permeability and T-cell transmigration by proteolysis of vascular endothelial cadherin. Circ Res. 2008;102:1192-1201.
26. Moss ML, Bartsch JW. Therapeutic benefits from targeting of ADAM family members. Biochemistry. 2004;43:7227-7235.
27. Shimoda M, Hashimoto G, Mochizuki S, Ikeda E, Nagai N, Ishida S, Okada Y. Binding of ADAM28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leukocyte adhesion to endothelial cells. J Biol Chem. 2007;282:25864-25874.
28. Ham C, Levkau B, Raines EW, Herren B. ADAM15 is an adherens junction molecule whose surface expression can be driven by VE-cadherin. Exp Cell Res. 2002;279:239-247.
29. Crawley JT, Lam JK, Rance JB, Mollica LR, O'Donnell JS, Lane DA. Proteolytic inactivation of AD AMTS 13 by thrombin and plasmin. Blood. 2005;105:1085-1093.
30. Millichip MI, Dallas DJ, Wu E, Dale S, McKie N. The metallo-disintegrin ADAM 10 (MADM) from bovine kidney has type IV collagenase activity in vitro. Biochem Biophys Res Commun. 1998;245:594-598.
31. Raffetto JD, Khalil RA. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol. 2008;75: 346-359.
32. Rapti M, Atkinson SJ, Lee MH, Trim A, Moss M, Murphy G. The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition. Biochem J. 2008;411:433-439.
33. 2+ entry mechanisms of vascular contraction. J Vasc Surg. 2004;40:1001-1010.
34. + channels: relevance to varicose vein formation. J Vasc Surg. 2007;45:373-380.
35. 2+]i induced by RGD-containing peptide. Am J Physiol. 1997;272(4 pt 2):H2065-H2070.
36. Wu X, Mogford JE, Platts SH, Davis GE, Meininger GA, Davis MJ. Modulation of calcium current in arteriolar smooth muscle by αvβ3 and α5β1 integrin ligands. J Cell Biol. 1998;143:241-252.
37. Ito K, Okamoto I, Araki N, Kawano Y, Nakao M, Fujiyama S, Tomita K, Mimori T, Saya H. Calcium influx triggers the sequential proteolysis of extracellular and Cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts. Oncogene. 1999;18:7080-7090.
38. 2+ signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions. J Physiol. 2001;533(pt 2):433-445.
39. Xu Z, Yu Y, Duh EJ. Vascular endothelial growth factor upregulates expression of AD AMTS 1 in endothelial cells through protein kinase C signaling. Invest Ophthalmol Vis Sci. 2006;47:4059-4066.
40. Sanderson MP, Erickson SN, Gough PJ, Garton KJ, Wille PT, Raines EW, Dunbar AJ, Dempsey PJ. ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx. J Biol Chem. 2005;280:1826-1837.