ADAM-mediated shedding and adhesion: A vascular perspective

News in Physiological Sciences

Volumn 17, Issue 2, 2002, Pages 73-76

  Herren, Barbara ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DISINTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; METALLOPROTEINASE; PROTEIN ADAM 1; PROTEIN ADAM 12; PROTEIN ADAM 15; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; ATHEROSCLEROSIS; CELL ACTIVATION; ENDOTHELIUM CELL; HUMAN; LEUKOCYTE; LEUKOCYTE ADHERENCE; LEUKOCYTE MOTILITY; PATHOPHYSIOLOGY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER;

EID: 0036544727     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/nips.01373.2001     Document Type: Article

References (15)

1. ADAMs: Focus on the protease domain
2. RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction
3. L-selectin shedding regulates leukocyte recruitment
4. Expression of a disintegrin-like protein in cultured human vascular cells and in vivo
5. Three putative integrin ligands identified in human aortic smooth muscle cells
6. TNF induces internalization of the p 60 receptor and shedding of the p80 receptor
7. Membrane protein secretases
8. The cysteine-rich domain of human ADAM12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading
9. Neutrophil Mac-1 and MEL- 14 adhesion proteins inversely regulated by chemotactic factors
10. Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells
11. Atherosclerosis - An inflammatory disease
12. Soluble L-selectin is present in human plasma at high levels and retains functional activity
13. Metalloprotease-disintegrins: Modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding
14. Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3
15. Pulmonary hypoplasia in mice lacking tumor necrosis factor-a converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis