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Volumn 10, Issue 3, 2008, Pages 391-400

Solid-phase combinatorial synthesis of a Lysyl-tRNA Synthetase (LysRS) inhibitory library

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; DRUG DERIVATIVE; LYSINE TRANSFER RNA LIGASE; PROLINE;

EID: 45149109605     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc700157j     Document Type: Article
Times cited : (11)

References (52)
  • 28
    • 45149133416 scopus 로고    scopus 로고
    • Cubist Pharmaceuticals Inc. U.S. Patent 5
    • (a) Cubist Pharmaceuticals Inc. U.S. Patent 5,726,195, 1998.
    • (1998) , vol.726 , Issue.195
  • 29
    • 45149115604 scopus 로고    scopus 로고
    • Intl. Patent WO 98/41215
    • (b) Cubist Pharmaceuticals Inc. Intl. Patent WO 98/41215, 1998.
    • (1998)
  • 43
    • 45149121113 scopus 로고    scopus 로고
    • In the case of hydroxyproline, the hydroxyl group was maintained free. The use of the alcohol-protected hydroxyproline with this resin was discarded because in a control cleavage after deprotection of THP with p-toluensulfonic acid, the target compound 1b{1} was not detected, probably because of the premature compound cleavage
    • In the case of hydroxyproline, the hydroxyl group was maintained free. The use of the alcohol-protected hydroxyproline with this resin was discarded because in a control cleavage after deprotection of THP with p-toluensulfonic acid, the target compound 1b{1} was not detected, probably because of the premature compound cleavage.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.