Molecular recognition of tyrosinyl adenylate analogues by prokaryotic tyrosyl tRNA synthetases

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 11, 1999, Pages 2473-2485

  Brown, Pamela ^a   Richardson, Christine M ^a   Mensah, Lucy M ^a   O'Hanlon, Peter J ^a   Osborne, Neal F ^a   Pope, Andrew J ^a   Walker, Graham ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Amino acids and derivatives; Enzyme inhibitors; Homology modelling; Molecular modelling; X ray crystal structures

Indexed keywords

ADENOSINE PHOSPHATE; TYROSINE TRANSFER RNA LIGASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; GEOBACILLUS STEAROTHERMOPHILUS; MOLECULAR RECOGNITION; NONHUMAN; X RAY CRYSTALLOGRAPHY;

ADENINE; ADENOSINE MONOPHOSPHATE; AMINO ACID SEQUENCE; BACILLUS STEAROTHERMOPHILUS; BINDING SITES; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATES; PROTEIN BINDING; RIBOSE; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; TYROSINE; TYROSINE-TRNA LIGASE;

GEOBACILLUS STEAROTHERMOPHILUS; PROKARYOTA; STAPHYLOCOCCUS AUREUS;

EID: 0033490426     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00192-3     Document Type: Article

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