Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives

Expert Opinion on Investigational Drugs

Volumn 9, Issue 8, 2000, Pages 1767-1775

  Tao, J ^a   Schimmel, P ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Aminoacyl tRNA synthetase; Antibiotic resistance; Drug target; High throughput screening; Intermediate based inhibitor

Indexed keywords

2 AMINO 4 METHYLENECYCLOPENTANECARBOXYLIC ACID; 2 AMINOCYCLOPENTANECARBOXYLIC ACID; AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; ANTIINFECTIVE AGENT; BORRELIDIN; CB 138; CB 168; CB 286; CB 432; CHIMERIC PROTEIN; DNA; ENZYME INHIBITOR; FURANOMYCIN; GLUTATHIONE TRANSFERASE; GRANATICIN; INDOLMYCIN; ISOLEUCINE; NEW DRUG; OCHRATOXIN; PSEUDOMONIC ACID; PURPUROMYCIN; SB 236996; TRANSFER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIAL INFECTION; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HEALTH CARE; MOUSE; NONHUMAN; PHARMACEUTICAL CARE; PHARMACOPHORE; REVIEW;

EID: 0033884057     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.9.8.1767     Document Type: Review

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