Toll-like receptor stimulation induces higher TNF-α secretion in peripheral blood mononuclear cells from patients with hyper IgE syndrome

International Archives of Allergy and Immunology

Volumn 146, Issue 3, 2008, Pages 190-194

  Yeganeh, Mehdi ^a   Henneke, Philipp ^b   Rezaei, Nima ^a   Ehl, Stephan ^b   Thiel, Doerte ^b   Matamoros, Nuria ^d   Pietrogrande, Cristina ^f   Espanol, Teresa ^e   Litzman, Jiri ^h   Franco, Jose L ⁱ   Sanal, Ozden ^j   Kilic, Sara S ^k   Breborowicz, Anna ^l   Plebani, Alessandro ^g   Renner, Ellen ^c   Rothenfusser, Simon ^c   Hawn, Thomas R ^m   Woellner, Cristina ⁿ   Grimbacher, Bodo ⁿ  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF FREIBURG   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^e HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^f UNIVERSITY OF MILAN   (Italy)

^g UNIVERSITY OF BRESCIA   (Italy)

^h ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

ⁱ UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^j HACETTEPE UNIVERSITY   (Turkey)

^k ULUDAG UNIVERSITY   (Turkey)

^l POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^m UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

ⁿ UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

Hyper IgE syndrome; TNF ; Toll like receptor

Indexed keywords

INTERLEUKIN 8; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN CELL; HYPER IGE SYNDROME; LUNG CYST; MALE; MONONUCLEAR CELL; MUCOCUTANEOUS CANDIDIASIS; PNEUMONIA; PRIORITY JOURNAL; SKIN ABSCESS;

COHORT STUDIES; FEMALE; HUMANS; INTERLEUKIN-8; JOB'S SYNDROME; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 45149083315     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000115886     Document Type: Article

References (15)

1. Grimbacher B, Holland SM, Puck JM: Hyper-IgE syndromes. Immunol Rev 2005;203:244-250.
2. Renner ED, Puck JM, Holland SM, Schmitt M, Weiss M, Frosch M, Bergmann M, Davis J, Belohradsky BH, Grimbacher B: Autosomal recessive hyperimmunoglobulin E syndrome: a distinct disease entity. J Pediatr 2004;144:93-99.
3. Davis SD, Schaller J, Wedgwood RJ: Job's syndrome: recurrent, 'cold', staphylococcal abscesses. Lancet 1966;i:1013-1015.
4. Minegishi Y, Saito M, Morio T, Watanabe K, Agematsu K, Tsuchiya S, Takada H, Hara T, Kawamura N, Ariga T, Kaneko H, Kondo N, Tsuge I, Yachie A, Sakiyama Y, Iwata T, Bessho F, Ohishi T, Joh K, Imai K, Kogawa K, Shinohara M, Fujieda M, Wakiguchi H, Pasic S, Abinun M, Ochs HD, Renner ED, Jansson A, Belohradsky BH, Metin A, Shimizu N, Mizutani S, Miyawaki T, Nonoyama S, Karasuyama H: Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 2006;25:745-755.
5. Woellner C, Schaffer AA, Puck JM, Renner ED, Knebel C, Holland SM, Plebani A, Grimbacher B: The hyper IgE syndrome and mutations in TYK2. Immunity 2007;26:535.
6. Trinchieri G, Sher A: Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 2007;7:179-190.
7. Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, Elbim C, Hitchcock R, Lammas D, Davies G, Al-Ghonaium A, Al-Rayes H, Al-Jumaah S, Al-Hajjar S, Al-Mohsen IZ, Frayha HH, Rucker R, Hawn TR, Aderem A, Tufenkeji H, Haraguchi S, Day NK, Good RA, Gougerot-Pocidalo MA, Ozinsky A, Casanova JL: Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003;299:2076-2079.
8. Casrouge A, Zhang S Y, Eidenschenk C, Jouanguy E, Puel A, Yang K, Alcais A, Picard C, Mahfoufi N, Nicolas N, Lorenzo L, Plancoulaine S, Senechal B, Geissmann F, Tabeta K, Hoebe K, Du X, Miller RL, Heron B, Mignot C, de Villemeur TB, Lebon P, Dulac O, Rozenberg F, Beutler B, Tardieu M, Abel L, Casanova JL: Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 2006;314:308-312.
9. Hawn TR, Ozinsky A, Williams LM, Rodrigues S, Clark A, Pham U, Hill HR, Ochs H, Aderem A, Liles WC: Hyper-IgE syndrome is not associated with defects in several candidate Toll-like receptor pathway genes. Hum Immunol 2005;66:842-847.
10. Renner ED, Pawlita I, Hoffmann F, Hornung V, Hartl D, Albert M, Jansson A, Endres S, Hartmann G, Belohradsky BH, Rothenfusser S: No indication for a defect in Toll-like receptor signaling in patients with hyper-IgE syndrome. J Clin Immunol 2005;25:321-328.
11. Grimbacher B, Schaffer AA, Holland SM, Davis J, Gallin JI, Malech HL, Atkinson TP, Belohradsky BH, Buckley RH, Cossu F, Espanol T, Garty BZ, Matamoros N, Myers LA, Nelson RP, Ochs HD, Renner ED, Wellinghausen N, Puck JM: Genetic linkage of hyper-IgE syndrome to chromosome 4. Am J Hum Genet 1999;65:735-744.
12. Taylor PC, Williams RO, Feldmann M: Tumour necrosis factor α as a therapeutic target for immune-mediated inflammatory diseases. Curr Opin Biotechnol 2004;15:557-563.
13. Gilbert L, He X, Farmer P, Boden S, Kozlowski M, Rubin J, Nanes MS: Inhibition of osteoblast differentiation by tumor necrosis factor-α. Endocrinology 2000;141:3956-3964.
14. Jilka RL, Weinstein RS, Bellido T, Parfitt AM, Manolagas SC: Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines. J Bone Miner Res 1998;13:793-802.
15. Horwood NJ, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T, Brennan FM, Webster D, Foxwell BM: Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production. J Immunol 2006;176:3635-3641.