Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Kim, Young Rae ^a   Sun, Hee Sun ^a   Won, Minho ^a   Ah, Kyeong Ah ^a   Kim, Jin Man ^a   Choi, Byung Lyul ^a   Lee, Hyunji ^a   Hong, Jang Hee ^a   Park, Jongsun ^a   Seok, Jeong Ho ^a   Wook, Dong Wook ^a   Shong, Minho ^a   Park, Seung Kiel ^a   Min, Gang Min ^a  

^a Chungnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BUTANOL; LUCIFERASE; PERVANADATE; PHOSPHOLIPASE D; PHOSPHOLIPASE D2; PROTEIN PATCHED; PROTEIN RET; STAT3 PROTEIN; TRITIUM; TYROSINE;

ANAPLASTIC CARCINOMA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIPID HYDROLYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYROID PAPILLARY CARCINOMA; WESTERN BLOTTING; ADULT; AGED; CULTURE TECHNIQUE; ENZYMOLOGY; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; PAPILLARY CARCINOMA; PATHOLOGY; PHOSPHORYLATION; THYROID TUMOR; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, PAPILLARY; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; ENZYME ACTIVATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOSPHOLIPASE D; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-RET; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; THYROID NEOPLASMS; TRANSCRIPTIONAL ACTIVATION;

EID: 44949200152     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-144     Document Type: Article

References (35)

1. Tallini G Asa SL RET oncogene activation in papillary thyroidcarcinoma. Adv Anat Pathol 2001, 8:345-354. 10.1097/00125480-200111000-00005
2. Ciampi R Nikiforov YE RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis Endocrinology 2007, 148(3):936-941.
3. Nikiforov YE RET/PTC rearrangement in thyroid tumors. Endocr Pathol 2002, 13:3-16. 10.1385/EP:13:1:03
4. Saenko V Rogounovitch T Shimizu-Yoshida Y Abrosimov A Lushnikov E Roumiantsev P Matsumoto N Nakashima M Meirmanov S Ohtsuru A Namba H Tsyb A Yamashita S Novel tumorigenic rearrangement, rfp/ret, in a papillary thyroidcarcinoma from externally irradiated patient. Mutat Res 2003. 527:81-90.
5. Baloch ZW LiVolsi VA Pathologic diagnosis of papillarythyroid carcinoma: today and tomorrow. Expert Rev Mol Diagn 2005, 5:573-584. 10.1586/ 14737159.5.4.573
6. Santoro M Melillo RM Grieco M Berlingieri MT Vecchio G Fusco A Pilotti S The TRK and RET tyrosine kinase oncogenes cooperatewith ras in the neoplastic transformation of a rat thyroidepithelial cell line. Cell Growth Differ 1993, 4:77-84.
7. Jhiang SM Sagartz JE Tong Q Parker-Thornburg J Capen CC Cho JY Xing S Ledent C Targeted expression of the ret/PTC1oncogene induces papillary thyroid carcinomas. Endocrinology 1996, 137:375-378. 10.1210/en.137.1.375
8. Santoro M Chiapetta G Cerrato A Salvatore D Zhang L Manzo G Picone A Portella G Santelli G Vecchio G Fusco A Development of thyroid papillary carcinomas secondary totissue-specific expression of the RET/PTC1 oncogene in transgenicmice. Oncogene 1996. 12:1821-1826.
9. Powell DJ Jr Russell J Nibu K Li G Rhee E Liao M Goldstein M Keane WM Santoro M Fusco A Rothstein JL The RET/PTC3 oncogene: Metastatic solid-type papillary carcinomas in murinethyroids. Cancer Res 1998. 58:5523-5528.
10. Santoro M Melillo RM Fusco A RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture Eur J Endocrinol 2006, 155(5):645-653. 10.1530/eje.1.02289
11. Kodama Y Asai N Kawai K Jijiwa M Murakumo Y Ichihara M Takahashi M The RET proto-oncogene: A molecular therapeutic target in thyroid cancer Cancer Sci 2005, 96(3):143-148. 10.1111/j.1349-7006.2005.00023.x
12. Hwang JH Kim DW Suh JM Kim H Song JH Hwang ES Park KC Chung HK Kim JM Lee TH Yu DY Shong M Activation of Signal Transducer and Activator ofTranscription 3 by Oncogenic RET/PTC (Rearrangedin Transformation/ Papillary Thyroid Carcinoma)Tyrosine Kinase: Roles in Specific Gene Regulationand Cellular Transformation Molecular Endocrinology 2003, 17(6):1155-1166.
13. Exton JH Regulation of phospholipase D. Biochim Biophys Acta 1999, 1439(2):121-133.
14. Colley WC Sung TC Roll R Jenco J Hammond SM Altshuller Y Bar-Sagi D Morris AJ Frohman MA Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr Biol 1997. 7(3):191-201. 10.1016/ S0960-9822(97)70090-
15. Steed PM Clark KL Boyar WC Lasala DJ Characterization of human PLD2 and the analysis of PLD isoform splice variants. FASEB J 1998, 12(13):1309-1317.
16. Hammond SM Jenco JM Nakashima S Cadwallader K Gu Q Cook S Nozawa Y Prestwich GD Frohman MA Morris AJ Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha. J Biol Chem 1997, 272(6):3860-3868.
17. Han JM Kim Y Lee JS Lee CS Lee BD Ohba M Kuroki T Suh PG Ryu SH Localization of phospholipase D1 to caveolin-enriched membrane via palmitoylation: Implications for epidermal growth factor signaling. Mol Biol Cell 2002, 13(11):3976-3988. 10.1091/mbc.E02-02-0100
18. Liscovitch M Czarny M Fiucci G Lavie Y Tang X Localization and possible functions of phospholipase D isozymes. Biochim Biophys Acta 1999, 1439(2):245-263.
19. Moss J Vaughan M Molecules in the ARF orbit. J Biol Chem 1998, 273(34):21431-21434. 10.1074/jbc.273.34.21431
20. D'Souza-Schorey C Li G Colombo MI Stahl PD A regulatory role for ARF6 in receptor-mediated endocytosis. Science 1995, 267(5201):1175-1178. 10.1126/science.7855600
21. Min DS Kwon TK Park WS Chang JS Park SK Ahn BH Ryoo ZY Lee YH Lee YS Rhie DJ Yoon SH Hahn SJ Kim MS Jo YH Neoplastic transformation and tumorigenesis associated with overexpression of phospholipase D isozymes in cultured murine fibroblasts. Carcinogenesis 2001, 22(10):1641-1647. 10.1093/carcin/22.10.1641
22. Lucas L del Peso L Rodríguez P Penalva V Lacal JC Ras protein is involved in the physiological regulation of phospholipase D by platelet derived growth factor. Oncogene 2000, 19(3):431-437. 10.1038/ sj.onc.1203323
23. Sung JY Lee SY Min DS Eom TY Ahn YS Choi MU Kwon YK Chung KC Differential activation of phospholipases by mitogenic EGF and neurogenic PDGF in immortalized hippocampal stem cell lines. J Neurochem 2001, 78(5):1044-1053. 10.1046/j.1471-4159.2001.00491.x
24. Sa G Das T Basic fibroblast growth factor stimulates cytosolic phospholipase A2, phospholipase C-gamma1 and phospholipase D through distinguishable signaling mechanisms. Mol Cell Biochem 1999, 198(1-2):19-30. 10.1023/A:1006970710298
25. Banno Y Takuwa Y Yamada M Takuwa N Ohguchi K Hara A Nozawa Y Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cells. Biochem J 2003, 369(Pt 2):363-368. 10.1042/BJ20021368
26. Saito M Iwadate M Higashimoto M Ono K Takebayashi Y Takenoshita S Expression of phospholipase D2 in human colorectal carcinoma. Oncol Rep 2007, 18(5):1329-1334.
27. Joseph T Wooden R Bryant A Zhong M Lu Z Foster DA Transformation of cells overexpressing a tyrosine kinase by phospholipase D1 and D2. Biochem Biophys Res Commun 2001, 289(5):1019-1024. 10.1006/bbrc.2001.6118
28. Ahn BH Kim SY Kim EH Choi KS Kwon TK Lee YH Chang JS Kim MS Jo YH Min DS Transmodulation between phospholipase D and c-Src enhances cell proliferation. Mol Cell Biol 2003, 23(9):3103-3115. 10.1128/ MCB.23.9.3103-3115.2003
29. Zhong M Shen Y Zheng Y Joseph T Jackson D Foster DA Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. Biochem Biophys Res Commun 2003, 302(3):615-619. 10.1016/S0006-291X(03)00229-8
30. Lee SD Lee BD Han JM Kim JH Kim Y Suh PG Ryu SH Phospholipase D2 activity suppresses hydrogen peroxide-induced apoptosis in PC12 cells. J Neurochem 2000, 75(3):1053-1059. 10.1046/j.1471-4159.2000.0751053.x
31. Ho WT Xie Z Zhao ZJ Exton JH Tyrosine phosphorylation of phospholipase D1 by v-Src does not per se result in activation. Cell Signal 2005, 17(6):691-699. 10.1016/j.cellsig.2004.10.007
32. Jossart GH Greulich KM Siperstein AE Duh Q Clark OH Weier HU Molecular and cytogenetic characterization of a t(1;10;21) translocation in the human papillary thyroid cancer cell line TPC-1 expressing the ret/H4 chimeric transcript. Surgery 1995, 118(6):1018-1023. 10.1016/ S0039-6060(05)80108-4
33. Viglietto G Chiappetta G Martinez-Tello FJ Fukunaga FH Tallini G Rigopoulou D Visconti R Mastro A Santoro M Fusco A RET/PTC oncogene activation is an early event in thyroid carcinogenesis. Oncogene 1995, 11(6):1207-1210.
34. Wang L Cummings R Zhao Y Kazlauskas A Sham JK Morris A Georas S Brindley DN Natarajan V Involvement of phospholipase D2 in lysophosphatidate-induced transactivation of platelet-derived growth factor receptor-beta in human bronchial epithelial cells. J Biol Chem 2003, 278(41):39931-39940. 10.1074/jbc.M302896200
35. Bromberg JF Wrzeszczynska MH Devgan G Zhao Y Pestell RG Albanese C Darnell JE Jr Stat3 as an oncogene. Cell 1999, 98(3):295-303. 10.1016/ S0092-8674(00)81959-5