Assessment of cell engineering strategies for improved therapeutic protein production in CHO cells

Biotechnology Journal

Volumn 3, Issue 5, 2008, Pages 624-630

  Mohan, Chaya ^a   Kim, Yeon Gu ^a   Koo, Jane ^a   Lee, Gyun Min ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Apoptosis; Chinese hamster ovary cells; Molecular chaperones; Specific productivity

Indexed keywords

HAMSTER OVARY CELLS; MOLECULAR CHAPERONES; SPECIFIC PRODUCTIVITY;

CELL CULTURE; CELL DEATH; PROTEINS;

BIOTECHNOLOGY;

CASPASE; CHAPERONE; FC RECEPTOR; FC RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR FUSION PROTEIN; INTERLEUKIN 15; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; THROMBOPOIETIN; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; APOPTOSIS; BIOENGINEERING; CELL CULTURE; CELL GROWTH; CELL SURVIVAL; CHO CELL; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ENGINEERING; GROWTH REGULATION; KOREA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SYNTHESIS; REVIEW;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GENETIC ENHANCEMENT; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; TECHNOLOGY ASSESSMENT, BIOMEDICAL;

CRICETULUS GRISEUS;

EID: 44949158950     PISSN: 18606768     EISSN: None     Source Type: Journal    
DOI: 10.1002/biot.200700249     Document Type: Review

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