Parecoxib versus dipyrone (metamizole) for postoperative pain relief after hysterectomy: A prospective, single-centre, randomized, double-blind trial

Clinical Drug Investigation

Volumn 28, Issue 7, 2008, Pages 421-428

  Soltesz, Stefan ^a   Gerbershagen, Mark U ^b   Pantke, Bernhard ^a   Eichler, Frank ^a   Molter, Gerd ^a  

^a KLINIKUM LEVERKUSEN   (Germany)

^b UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Cyclo oxygenase 2 inhibitors, therapeutic use; Dipyrone, therapeutic use; Hysterectomy; Nonsteroidal anti inflammatories, therapeutic use; Parecoxib, therapeutic use; Postoperative pain

Indexed keywords

DIPYRONE; PARECOXIB; PIRITRAMIDE; PLACEBO;

ADULT; AGED; ANALGESIC ACTIVITY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FACIAL NERVE PARALYSIS; FEMALE; HEMODYNAMICS; HUMAN; INJECTION SITE PAIN; LUNG DISEASE; NAUSEA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEDATION; SIDE EFFECT; TREATMENT OUTCOME; VAGINAL HYSTERECTOMY; VENTILATORY DEPRESSION; VISUAL ANALOG SCALE; VOMITING;

ADOLESCENT; ADULT; AGED; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE INHIBITORS; DIPYRONE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYSTERECTOMY, VAGINAL; INJECTIONS, INTRAVENOUS; ISOXAZOLES; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PIRINITRAMIDE; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 44949100248     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-200828070-00003     Document Type: Article

References (26)

1. Barton SF, Langeland FF, Snabes MC, et al. Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery. Anesthesiology 2002; 97: 306-14
2. Desjardins PJ, Shu VS, Recker DP, et al. A single preoperative oral dose of valdecoxib, a new cyclooxygenase-2 specific inhibitor, relieves post-oral surgery or bunionectomy pain. Anesthesiology 2002; 97: 565-73
3. Hubbard RC, Naumann TM, Traylor L, et al. Parecoxib sodium has opioid-sparing effects in patients undergoing total knee arthroplasty under spinal anaesthesia. Br J Anaesth 2003; 90: 166-72
4. Ng A, Smith G, Davidson AC. Analgesic effects of parecoxib following total abdominal hysterectomy. Br J Anaesth 2003; 90: 746-9
5. Tang J, Li S, White PF, et al. Effect of parecoxib, a novel intravenous cyclooxygenase type-2 inhibitor, on the postoperative opioid requirement and quality of pain control. Anesthesiology 2002; 96: 1305-9
6. Malan Jr TP, Gordon S, Hubbard R, et al. The cyclooxygenase-2-specific inhibitor parecoxib sodium is as effective as 12mg of morphine administered intramuscularly for treating pain after gynaecologic laparotomy surgery. Anesth Analg 2005; 100: 454-60
7. Clemett D, Goa KL. Celecoxib: A review of its use in osteoarthritis, rheumatoid arthritis and acute pain. Drugs 2000; 59: 957-80
8. Hegi TR, Bombeli T, Seifert B, et al. Effect of rofecoxib on platelet aggregation and blood loss in gynaecological and breast surgery compared with diclofenac. Br J Anaesth 2004; 92: 523-31
9. Morrison BW, Christensen S, Yuan W, et al. Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in postdental surgery pain: a randomized, controlled trial. Clin Ther 1999; 21: 943-53
10. Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000; 343: 1520-8
11. Leese PT, Hubbard RC, Karim A, et al. Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial. J Clin Pharmacol 2000; 40: 124-32
12. Noveck RJ, Laurent A, Kuss ME, et al. The COX-2 specific inhibitor, parecoxib sodium, does not impair platelet function in healthy elderly and non-elderly individuals. Clin Drug Invest 2001; 21: 465-76
13. Grundmann U, Wörnle C, Biedler A, et al. The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy. Anesth Analg 2006; 103: 217-22
14. Beaussier M, Weickmans H, Paugham C, et al. A randomized double-blind comparison between parecoxib sodium and propacetamol for parenteral postoperative analgesia after inguinal hernia repair in adult patients. Anesth Analg 2005; 100: 1309-15
15. Remy C, Marret E, Bonnet F. State of the art of paracetamol in acute pain therapy. Curr Opin Anaesthesiol 2006; 19: 562-5
16. Edwards JE, Meseguer F, Faura CC, et al. Single-dose dipyrone for acute postoperative pain. Cochrane Database Syst Rev 2001; (3): CD003227
17. Ibanez L, Vidal X, Ballarin E, et al. Agranulocytosis associated with dipyrone (metamizol). Eur J Clin Pharmacol 2005; 60: 821-9
18. Vlahov V, Bacracheva N, Tontcheva D, et al. Genetic factors and risk of agranulocytosis from metamizol. Pharmacogenetics 1996; 6: 67-72
19. Blackburn A, Stevens JD, Wheatley RG, et al. Balanced analgesia with intravenous ketorolac and patient controlled morphine following lower abdominal surgery. J Clin Anesth 1995; 7: 103-8
20. Puolakka PAE, Puura AIE, Pirhonen RA, et al. Lack of analgesic effect of parecoxib following laparoscopic cholecystectomy. Acta Anaesthesiol Scand 2006; 50: 1027-32
21. Burns JW, Aitken HA, Bullingham RE, et al. Double-blind comparison of the morphine sparing effect of continuous and intermittent i.m. administration of ketorolac. Br J Anaesth 1991; 67: 235-8
22. Gillies GW, Kenny GN, Bullingham RE, et al. The morphine sparing effect of ketorolac tromethamine: a study of a new, parenteral non-steroidal anti-inflammatory agent after abdominal surgery. Anaesthesia 1987; 42: 727-31
23. Strom BL, Berlin JA, Kinman JL, et al. Parenteral ketorolac and risk of gastrointestinal and operative site bleeding: a postmarketing surveillance study. JAMA 1996; 275: 376-82
24. Hedenmalm K, Spigset O. Agranulocytosis and other blood dyscrasias associated with dipyrone (metamizole). Eur J Clin Pharmacol 2002; 58: 265-74
25. Bouillon T, Kietzmann D, Port R, et al. Population pharmacokinetics of piritramide in surgical patients. Anesthesiology 1999; 90: 7-15
26. Nussmeier NA, Whelton AA, Brown MT, et al. Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med 2005; 352: 1081-91