Genetic factors and risk of agranulocytosis from metamizol

Pharmacogenetics

Volumn 6, Issue 1, 1996, Pages 67-72

  Vlahov, V ^a,c   Bacracheva, N ^a   Tontcheva, D ^a   Naumova, E ^b   Mavrudieva, M ^a   Ilieva, P ^a   Michailova, A ^b  

^a Department of Clinical Pharmacology ^*  (Bulgaria)

^b MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^c UNIVERSITY HOSPITAL 'QUEEN GIOVANNA'   (Bulgaria)

Author keywords

agranulocytosis; chromosome aberrations; HLA system; metamizol; N acetylation

Indexed keywords

ACYLTRANSFERASE; DIPYRONE; GENE PRODUCT; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEMOGLOBIN; HLA A2 ANTIGEN; HLA ANTIGEN;

ADULT; AGRANULOCYTOSIS; ALLELE; ARTICLE; BLOOD GROUP ABO SYSTEM; BLOOD GROUP RHESUS SYSTEM; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG USE; ENZYME ACTIVITY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HAPLOTYPE; HEREDITY; HUMAN; MALE; PHENOTYPE; PRIORITY JOURNAL; RISK;

ABO BLOOD-GROUP SYSTEM; ACETYLATION; ADULT; AGRANULOCYTOSIS; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 2; DIPYRONE; FEMALE; HLA ANTIGENS; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC; RISK FACTORS; SEX FACTORS;

EID: 0029979487     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199602000-00005     Document Type: Article

References (25)

1. Baur MP, Albert ED, Mayr WR. Population analysis on the basis of deduced haplotype from random familie histocompatability testing. Germany: Springer Verlag. 1984: 333-341.
2. Beutler E, Mitchel M. Special modifications of the fluorescent screening method for G6PD deficiency. Blood 1968: 32, 816.
3. Brewer G, Tarlow A, Alving A. Methemoglobin reduction test. A new simple in vitro test for identifying primaquine sensitivity. Bull WHO 1960: 22, 683.
4. Cohen MM. Chromosome instability syndromes. Ataxia-telangiectasia. Adv Human Genet 1989: 18, 96-102.
5. Haldane JBS. The estimation and significance of the logarithm of a ratio of frequencies. Ann Hum Genet 1955: 20, 309-311.
6. Girdwood RH (ed). Blood disorders due to drugs and other agents. Amsterdam: Exerpta Medica, 1974.
7. Grant DM, Tang K, Kalow W. A simple test for acetylator phenotype using caffeine. Br J Clin Pharmacol 1984: 17, 459-464.
8. Ivanova R, Naumova E, Lepage V, Djoulak S, Yordanov Y, Loste MN, Charron D. HLA-DRB, DqA1, DqB1 DNA polymorphism in the Bulgarian population (Bulgarian HLA class II allele frequencies). Tissue Antigens 1995: (in press).
9. Jaspers NGJ, Taalman RDF, Baan C. Patients with an inherited syndrome characterized by immunodeficiency and chromosomal instability: genetic relationship to ataxia telangiectasia. Am J Hum Genet 1988: 42, 66-75.
10. Kaufman D, Kelly J, Levy M, Shapiro S (eds). The drug etiology of agranulocytosis and aplastic anemia. Oxford: University Press 1991: 176.
11. Kleinbaum DG, Kupper LL, Morgenstern H. Measures of potential impact and summary of the measures. In: Epidemiologic research. New York: Van Nostrand Reinhold. 1982: 159.
12. Lieberman JA, Yunis F, Egea E, Canoso RT, Kane JM, Yunis EJ. HLA-B38, DR4, DQW3 and clozapine-induced agranulocytosis in Jewish patients with schisophrenia. Arch Gen Psych 1990: 47, 945-948.
13. Naumova E. Immunological investigation in patients with kidney transplantation. Thesis. Medical Academy. Sofia, 1990.
14. Naumova E, Mihailova A, Nesheva I, Stefanova G. A fast HLA-antigens class I and II typing method with cells isolated directly from the blood by antibody coated magnetic spheres. Savr Med 1990: XL (3), 26-29.
15. Pfister GM, Hanson DR, Roerig IL, Landboom R, Popkin MK. Clozapine-induced agranulocytosis in native Americans: HLA typing and further support for immune-mediated mechanisms. J Clin Psych 1992: 53, 242-244.
16. Saiki RK, Wash PS, Levenson CH, Ellich HA. Genetic analysis of amplified DNA with immobilized sequences-specific oligonucleotide probes. Proc Natl Acad Sci USA 1989: 86, 6230-6234.
17. Svejgaard A, Jersil C, Nielsen LS, Bodmer WF. HL-A antigens and disease. Statistical and genetical considerations. Tissue Antigens 1974: 4, 95-105.
18. Svejgaard A, Ryder LP. HLA and disease associations: detecting the strongest association. Tissue Antigens 1994: 43, 18-27.
19. Tenth International Workshop on Human Gene Mapping, Human Gene Mapping 10, New Haven Conference 1989: 51, 1-4.
20. Tinz O, Rossi E. Morphological demonstration of two red cell populations in human females heterozygous for G6PD deficiency. Nature 1964: 202-206.
21. Vartdal F, Gaudernack G, Funderund S, Bratlie A. HLA class I and II typing using cells positively selected gram blood by immunomagnetic isolation - a fast and reliable technique. Tissue Antigens 1986: 28, 301-312.
22. Vlahov V, Bacracheva N. Agranulocytosis and dipyrone. Lancet 1989: 18, 1215.
23. Yunis JJ, Lieberman JA, Yunis EJ. Major histocompatibility complex associations with clozapine-induced agranulocytosis. The USA experience. Drug Safety 1992: 7 Suppl.1, 7-9.
24. Woolf B. On estimating the relation between blood group and disease. Ann Hum Genet 1955: 19, 251-253.
25. Zylber-Katz E, Granit L, Levy M. Formation and excretion of dipyrone metabolites in man. Eur J Clin Pharmacol 1992: 42, 187-191.