Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein

Journal of Biological Chemistry

Volumn 283, Issue 16, 2008, Pages 11038-11049

  Messick, Troy Eugene ^a   Russell, Nathaniel Scott ^c,d   Iwata, Ayaka Jennifer ^a,b   Sarachan, Kathryn Lorenz ^a,b   Shiekhattar, Ramin ^a,e   Shanks, John R ^c   Reyes Turcu, Francisca E ^c   Wilkinson, Keith D ^c   Marmorstein, Ronen ^a,b,f  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; CRYSTAL STRUCTURE; DEGRADATION; ELECTRIC RESISTANCE; ENZYME ACTIVITY; ENZYMES; MAMMALS; ORGANIC ACIDS; PHOTODEGRADATION; TUMORS; YEAST;

CATALYTIC SITES; DEGRADATION PATHWAYS; DEUBIQUITINATING ACTIVITIES; DEUBIQUITINATING ENZYMES; DO-MAINS; HYDROLASES; LINKED CHAINS; OVARIAN TUMORS; POLYUBIQUITIN CHAINS; PROTEIN FUNCTIONS; STRUCTURAL BASES; SUBCELLULAR LOCALIZATIONS; UBIQUITIN; UBIQUITINATION; X-RAY CRYSTAL STRUCTURES;

PROTEINS;

ADENOSINE TRIPHOSPHATE; LYSINE; PAPAIN; PROTEIN CDC48; PROTEIN OTU1; TUMOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; CDC48 PROTEIN; CELL CYCLE PROTEIN; CYSTEINE PROTEINASE; FUNGAL PROTEIN; OTUB2 PROTEIN, HUMAN; THIOL ESTER HYDROLASE;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROLYSIS; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; OVARY TUMOR; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DOSE RESPONSE; HUMAN; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

MAMMALIA;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGAL PROTEINS; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; THIOLESTER HYDROLASES; UBIQUITIN;

EID: 44849136272     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704398200     Document Type: Article

References (38)

1. Haglund, K., and Dikic, I. (2005) EMBO J. 24, 3353-3359
2. Reinstein, E., and Ciechanover, A. (2006) Ann. Intern. Med. 145, 676-684
3. Hochstrasser, M. (2000) Nat. Cell Biol. 2, 153-157
4. Pickart, C. M. (2001) Annu. Rev. Biochem. 70, 503-533
5. Fang, S., and Weissman, A. M. (2004) Cell Mol. Life Sci. 61, 1546-1561
6. Kerscher, O., Felberbaum, R., and Hochstrasser, M. (2006) Ann. Rev. Cell Dev. Biol. 22, 159-180
7. Babst, M. (2005) Traffic 6, 2-9
8. Amerik, A. Y., and Hochstrasser, M. (2004) Biochim. Biophys. Acta 1695, 189-207
9. Nanao, M. H., Tcherniuk, S. O., Chroboczek, J., Dideberg, O., Dessen, A., and Balakirev, M. Y. (2004) EMBO Rep. 5, 783-788
10. Evans, P. C., Smith, T. S., Lai, M. J., Williams, M. G., Burke, D. F., Heyninck, K., Kreike, M. M., Beyaert, R., Blundell, T. L., and Kilshaw, P. J. (2003) J. Biol. Chem. 278, 23180-23186
11. Kattenhorn, L. M., Korbel, G. A., Kessler, B. M., Spooner, E., and Ploegh, H. L. (2005) Mol. Cell 19, 547-557
12. Schlieker, C., Weihofen, W. A., Frijns, E., Kattenhorn, L. M., Gaudet, R., and Ploegh, H. L. (2007) Mol. Cell 25, 677-687
13. Verma, R., Aravind, L., Oania, R., McDonald, W. H., Yates, J. R., III, Koonin, E. V., and Deshaies, R. J. (2002) Science 298, 611-615
14. Steinhauer, W. R., Walsh, R. C., and Kalfayan, L. J. (1989) Mol. Cell. Biol. 9, 5726-5732
15. Rodesch, C., Geyer, P. K., Patton, J. S., Bae, E., and Nagoshi, R. N. (1995) Genetics 141, 191-202
16. Sass, G. L., Comer, A. R., and Searles, L. L. (1995) Dev. Biol. 167, 201-212
17. Glenn, L. E., and Searles, L. L. (2001) Mech. Dev. 102, 181-191
18. Makarova, K. S., Aravind, L., and Koonin, E. V. (2000) Trends Biochem. Sci. 25, 50-52
19. Evans, P. C., Ovaa, H., Hamon, M., Kilshaw, P. J., Hamm, S., Bauer, S., Ploegh, H. L., and Smith, T. S. (2004) Biochem. J. 378, 727-734
20. Lee, E. G., Boone, D. L., Chai, S., Libby, S. L., Chien, M., Lodolce, J. P., and Ma, A. (2000) Science 289, 2350-2354
21. Rumpf, S., and Jentsch, S. (2006) Mol. Cell 21, 261-269
22. Borodovsky, A., Ovaa, H., Kolli, N., Gan-Erdene, T., Wilkinson, K. D., Ploegh, H. L., and Kessler, B. M. (2002) Chem. Biol. 9, 1149-1159
23. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
24. Sheldrick, G. M., and Schneider, T. R. (1997) Methods Enzymol. 227, 319-343
25. Bricogne, G., Vonrhein, C., Flensburg, C., Schiltz, M., and Paciorek, W. (2003) Acta Crystallogr. 59, 2023-2030
26. Cowtan, K. D., and Main, P. (1996) Acta Crystallogr. 52, 43-48
27. Morris, R. J., Perrakis, A., and Lamzin, V. S. (2003) Methods Enzymol. 374, 229-244
28. Russell, N. S. (2005) Identification and Characterization of Polyubiquitin-binding Proteins in Saccharomyces cerevisiae Using Polyubiquitin Analogs, Ph.D. dissertation, Department of Biochemistry, Emory University, Atlanta, GA
29. Hu, M., Li, P., Song, L., Jeffrey, P. D., Chenova, T. A., Wilkinson, K. D., Cohen, R. E., and Shi, Y. (2005) EMBO J. 24, 3747-3756
30. Hicke, L., Schubert, H. L., and Hill, C. P. (2005) Nat. Rev. 6, 610-621
31. Wertz, I. E., O'Rourke, K. M., Zhou, H., Eby, M., Aravind, L., Seshagiri, S., Wu, P., Wiesmann, C., Baker, R., Boone, D. L., Ma, A., Koonin, E. V., and Dixit, V. M. (2004) Nature 430, 694-699
32. Shcherbik, N., and Haines, D. S. (2007) Mol. Cell 25, 385-397
33. Reyes-Turcu, F. E., Horton, J. R., Mullally, J. E., Heroux, A., Cheng, X., and Wilkinson, K. D. (2006) Cell 124, 1197-1208
34. Penengo, L., Mapelli, M., Murachelli, A. G., Confalonieri, S., Magri, L., Musacchio, A., Di Fiore, P. P., Polo, S., and Schneider, T. R. (2006) Cell 124, 1183-1195
35. Lee, S., Tsai, Y. C., Mattera, R., Smith, W. J., Kostelansky, M. S., Weissman, A. M., Bonifacino, J. S., and Hurley, J. H. (2006) Nat. Struct. Mol. Biol. 13, 264-271
36. Alam, S. L., Sun, J., Payne, M., Welch, B. D., Blake, B. K., Davis, D. R., Meyer, H. H., Emr, S. D., and Sundquist, W. I. (2004) EMBO J. 23, 1411-1421
37. Hu, M., Li, P., Li, M., Li, W., Yao, T., Wu, J. W., Gu, W., Cohen, R. E., and Shi, Y. (2002) Cell 111, 1041-1054
38. Misaghi, S., Galardy, P. J., Meester, W. J., Ovaa, H., Ploegh, H. L., and Gaudet, R. (2005) J. Biol. Chem. 280, 1512-1520