T-regulatory cells in systemic lupus erythematosus

Lupus

Volumn 17, Issue 5 SPEC. ISS., 2008, Pages 421-425

  La Cava, Antonio ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; AUTOIMMUNITY; CELL TYPE; DISEASE SEVERITY; HUMAN; IMMUNOMODULATION; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADAPTATION, BIOLOGICAL; ANIMALS; AUTOIMMUNITY; HUMANS; IMMUNITY, NATURAL; LUPUS ERYTHEMATOSUS, SYSTEMIC; T-LYMPHOCYTES, REGULATORY;

EID: 44849130760     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203308090028     Document Type: Review

References (38)

1. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389: 737-742.
2. Chen, Y, Inobe, J, Kuchroo, VK, et al. Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells. Proc Natl Acad Sci USA 1996; 93: 388-391.
3. Seddiki, N, Santner-Nanan, B, Martinson, J, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203: 1693-1700.
4. Hori, S, Nomura, T, Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-1061.
5. + T cells: sensing the environment. Trends Immunol 2008; 29: 12-17.
6. + regulatory T cells. Front Biosci 2008; 13: 1440-1446.
7. Fontenot, JD, Rasmussen, JP, Gavin, MA, Rudensky, AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 2005; 6: 1142-1151.
8. + regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol 2005; 6: 1152-1159.
9. Grossman, WJ, Verbsky, JW, Barchet, W, et al. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 2004; 21: 589-601.
10. Huang, CT, Workman, CJ, Flies, D, et al. Role of LAG-3 in regulatory T cells. Immunity 2004; 21: 503-513.
11. + Tregs and immune control. J Clin Invest 2004; 114: 1209-1217.
12. Mudd, PA, Teague, BN, Farris, AD. Regulatory T cells and systemic lupus erythematosus. Scand J Immunol 2006; 64: 211-218.
13. + regulatory T cell function. Science 2005; 309: 1380.
14. Viglianti, GA, Lau, CM, Hanley, TM, et al. Activation of autoreactive B cells by CpG dsDNA. Immunity 2003; 19: 837.
15. + T cell-mediated suppression by dendritic cells. Science 2003; 299: 1033.
16. Dai, J, Liu, B, Ngoi, SM, et al. TLR4 hyperresponsiveness via cell surface expression of heat shock protein gp96 potentiates suppressive function of regulatory T cells. J Immunol 2001; 178: 3219-3225.
17. Wu, X, Peng, SL. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum 2006; 54: 336.
18. Christensen, SR, Kashgarian, M, Alexopoulou, L, et al. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med 2005; 202: 321.
19. + regulatory T cells by peripheral expansion. J Immunol 2004; 173: 7259-7268.
20. Kang, HK, Michaels, MA, Berner, BR, Datta, SK. Very low-dose tolerance with nucleosomal peptides controls lupus and induces potent regulatory T cell subsets. J Immunol 2005; 174: 3247-3255.
21. 1 mice suppress in vitro production of antibodies to DNA. J Immunol 2004; 173: 3542-3548.
22. Kang, HK, Liu, M, Datta, SK. Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells. J Immunol 2007; 178: 7849-7858.
23. Sakaguchi, S, Sakaguchi, N, Asano, M, et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995; 155: 1151-1164.
24. + regulatory T cells. Nat Immunol 2003; 4: 330-360.
25. Chen, Y, Cuda, C, Morel, L. Genetic determination of T cell help in loss of tolerance to nuclear antigens. J Immunol 2005; 174: 7692.
26. Cuda, CM, Wan, S, Sobel, ES, et al. Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms. J Immunol 2007; 179: 7439-7447.
27. + T cell regulatory functions. J Immunol 2007; 178: 271-279.
28. Bagavant, H, Thompson, C, Ohno, K, et al. Differential effect of neonatal thymectomy on systemic and organ-specific autoimmune disease. Int Immunol 2002; 14: 1397.
29. + regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus. Arthritis Rheum 2005; 52: 1180-1184.
30. Scalapino, KJ, Tang, Q, Bluestone, JA, et al. Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells. J Immunol 2006; 177: 1451-1459.
31. Crispin, JC, Martinez, A, Alcocer-Varela, J. Quantification of regulatory T cells in patients with systemic lupus erythematosus. J Autoimmun 2003; 21: 273-276.
32. Miyara, M, Amoura, Z, Parizot, C, et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol 2005; 175: 8392-8400.
33. Mellor-Pita, S, Citores, MJ, Castejon, R, et al. Decrease of regulatory T cells in patients with systemic lupus erythematosus. Ann Rheum Dis 2006; 65: 553-554.
34. Alvarado-Sánchez, B, Hernández-Castro, B, Portales-Pérez, D, et al. Regulatory T cells in patients with systemic lupus erythematosus. J Autoimmun 2006; 27: 110-118.
35. + regulatory T cells in patients with systemic lupus erythematosus. Adv Exp Med Biol 2007; 601: 113-119.
36. Lee, JH, Wang, LC, Lin, YT, et al. Inverse correlation between CD4 regulatory T-cell population and autoantibody levels in pediatric patients with systemic lupus erythematosus. Immunology 2006; 117: 280.
37. high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol 2007; 178: 2579-2588.
38. Hahn, BH, Anderson, M, LE, E, La Cava, A. Anti-DNA Ig peptides promote regulatory T-cell activity in SLE patients. Arthritis Rheum In press.