Ig knock-in mice producing anti-carbohydrate antibodies: Breakthrough of B cells producing low affinity anti-self antibodies

Journal of Immunology

Volumn 180, Issue 6, 2008, Pages 3839-3848

  Benatuil, Lorenzo ^a   Kaye, Joel ^a   Cretin, Nathalie ^b   Godwin, Jonathan G ^a   Cariappa, Annaiah ^c   Pillai, Shiv ^c   Iacomini, John ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSIDASE; ANTIBODY; CARBOHYDRATE ANTIBODY; CARBOHYDRATE ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN M ANTIBODY; UNCLASSIFIED DRUG; ALPHA GALACTOSYL EPITOPE; ALPHA-GALACTOSYL EPITOPE; AUTOANTIBODY; GALACTOSYLTRANSFERASE; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M; N ACETYLLACTOSAMINIDE ALPHA 1,3 GALACTOSYLTRANSFERASE; N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE; TRISACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; CARDIAC GRAFT REJECTION; CELL MATURATION; CONTROLLED STUDY; GENE ISOLATION; HYBRIDOMA; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; ANIMAL; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; ENZYMOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; TRANSGENIC MOUSE;

ANIMALS; ANTIBODY SPECIFICITY; AUTOANTIBODIES; B-LYMPHOCYTE SUBSETS; BINDING SITES, ANTIBODY; CELL DIFFERENTIATION; CELLS, CULTURED; GALACTOSYLTRANSFERASES; HYBRIDOMAS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; TRISACCHARIDES;

EID: 44849093669     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.6.3839     Document Type: Article

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