Development and characterization of anti-Gal B cell receptor transgenic Gal-/- mice

Transplantation

Volumn 73, Issue 10, 2002, Pages 1549-1557

  Xu, Hui ^a   Sharma, Ajay ^a   Lei, Ying ^a   Okabe, Jeannine ^a   Wan, Hua ^a   Chong, Anita S F ^a   Logan, John S ^a   Byrne, Guerard W ^a  

^a Nextran   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; GALACTOSYLGALACTOSE; GALACTOSYLTRANSFERASE; IMMUNOGLOBULIN M ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0037182163     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200205270-00006     Document Type: Article

References (53)

1. Characterization and affinity isolation of xenoreactive human natural antibodies
2. Human natural anti-alpha-galactosyl IgG
3. Heterogeneity of human anti-pig natural antibodies cross-reactive with the Gal(alpha1,3)galactose epitope
4. Anti-Gal IgG antibodies in sera of newborn humans and baboons and its significance in pig xenotransplantation
5. Natural anti-pig xenoanti/body is absent in neonatal human serum
6. Interaction between human natural anti-α-galactosyl immunoglobulin G and bacteria of the human flora
7. Human natural anti-Gal IgG regulates alternative complement pathway activation on bacterial surfaces
8. Quantitation and characterization of anti-Galalpha1-3Gal antibodies in sera of 200 healthy persons
9. Anti-agalactosyl IgG antibodies and isotype profiles of rheumatoid factors in Sjögren's syndrome and rheumatoid arthritis
10. Elevated anti-galactosyl antibody titers in endemic goiter
11. Specific stimulation of Graves' disease thyrocytes by the natural anti-Gal antibody from normal and autologous serum
12. Simple radioimmunological assay of anti-alpha-galactosyl antibody (anti-Gal): Application to autoimmune thyroid diseases and thyroid-associated ophthalmopathy
13. Evaluation of the Galalpha-3Gal epitope as a host modification factor eliciting natural humoral immunity to enveloped viruses
14. Sensitization of cells and retroviruses to human serum by (α1-3) galactosyltransferase
15. One percent of human circulating b lymphocytes are capable of producing the natural anti-Gal antibody
16. Gal alpha (1,3)Gal, the major xenoantigen(s) recognised in pigs by human natural antibodies
17. Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon
18. Interaction of the natural anti-Gal antibody with alpha-galactosyl epitopes: A major obstacle for xenotransplantation in humans
19. Human complement regulatory proteins expressed in transgenic swine protect swine xenografts from humoral injury
20. Transgenic pigs expressing human CD59 and decay-accelerating factor produce an intrinsic barrier to complement-mediated damage
21. Life-supporting pig-to-baboon heart xenotransplantation
22. Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors
23. IG-therasorb immunoapheresis in orthotopic xenotransplantation of baboons with Landrace pig hearts
24. The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants
25. Intravenous synthetic agal saccharides delay hyperacute rejection following pig-to-baboon heart transplantation
26. Intravenous infusion of Galα1-3Gal oligosaccharides in baboons delays hyperacute rejection of porcine heart xenografts
27. Analysis of the control of the anti-Gal immune response in a non-human primate by an α-Gal trisaccharide-PEG conjugate
28. The humoral immune response in humans following cross-perfusion of porcine organs
29. Liver allotransplantation after extracorporeal hepatic support with transgenic (hCD55/hCD59) porcine livers
30. The α-1,3-galactosyltransferase knockout mouse
31. Oocyte Gal alpha 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse
32. Anti-galactose-α(1,3)galactose anti-body production in α1,3-galactosyltransferase gene knockout mice after xeno- and allotransplantation
33. Differential immune responses to α-Gal epitopes on xenografts and allografts: Implications for accommodation in xenotransplantation
34. The structure of anti-Gal immunoglobulin genes in naive and stimulated Gal knockout mice
35. Regulation of anti-DNA B cells in recombination-activating gene-deficient mice
36. Anti-galactose-α(1,3) galactose antibody production in α1,3-galactosyltransferase gene knockout mice after xeno and allo transplantation
37. Mac-1-negative B-1b phenotype of natural antibody-producing cells, including those responding to Galα1,3Gal epitopes in α1,3-galactosyltransferase-deficient mice
38. Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses
39. high Lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells
40. Comparative in vitro analysis of proliferation, Ig secretion, and Ig class switching by murine marginal zone and follicular B cells
41. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens
42. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
43. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
44. The site and stage of anti-DNA B-cell deletion
45. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
46. Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
47. Receptor editing in self-reactive bone marrow B cells
48. Receptor editing: An approach by autoreactive B cells to escape tolerance
49. B lymphocytes may escape tolerance by revising their antigen receptors
50. Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive
51. Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of α1,4-glycosyltransferases conserved in plants, insects, and mammals
52. The reducing end of alpha Gal oligosaccharides contributes to their efficiency in blocking natural antibodies of human and baboon sera
53. In vivo T-cell depletion enhances production of anti-GALalpha1,3GAL natural antibodies in alpha1,3-galactosyltransferase-deficient mice