Complex issues with examining diesel exhaust toxicity: Is the task getting easier or harder?

Experimental and Toxicologic Pathology

Volumn 60, Issue 2-3, 2008, Pages 135-140

  Madden, Michael C ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Allergy; Bioassay; Diesel exhaust; Emission regulations; Inflammation; Mutagenicity; Susceptibility

Indexed keywords

ALLERGY; ARTICLE; BIOASSAY; EXHAUST GAS; INFLAMMATION; MUTAGENICITY; PARTICULATE MATTER; TOXICITY;

ANIMAL TESTING ALTERNATIVES; CELLS, CULTURED; ENVIRONMENTAL EXPOSURE; HUMANS; INHALATION EXPOSURE; LUNG; LUNG DISEASES; MODELS, ANIMAL; PARTICULATE MATTER; TISSUE CULTURE TECHNIQUES; VEHICLE EMISSIONS;

ANIMALIA;

EID: 44749093209     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2008.01.002     Document Type: Article

References (30)

1. Cass G. Diesel engine contributions to atmospheric particles: measurement methods and atmospheric modeling approaches. In: Diesel Workshop: building a research strategy to improve risk assessment. Health Effects Institute Communication no. 7, Cambridge, MA, 1999.
2. deBruijne K, Sexton KG, Ebersviller S, Doyle M, Jeffries H, Jaspers I. Comparing the toxicity of fresh and aged diesel exhaust using a newly developed in vitro exposure system. Toxicologist 2007;A508.
3. DeMarini D, Brooks LR, Warren SH, Kobayashi T, Gilmour MI, Singh P. Bioassay-directed fractionation and salmonella mutagenicity of automobile and forklift diesel exhaust particles. Environ Health Perspect 2004;112:814-9.
4. Diaz-Sanchez D., Tsien A., Fleming J., and Saxon A. Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern. J Immunol 158 (1997) 2406-2413
5. Gilboa S.M., Mendola P., Olshan A.F., Langlois P.H., Savitz D.A., Loomis D., et al. Relation between ambient air quality and selected birth defects, seven county study, Texas, 1997-2000. Am J Epidemiol 162 (2005) 238-252
6. Gilliland F.D., Li Y.F., Saxon A., and Diaz-Sanchez D. Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. Lancet 363 (2004) 119-125
7. Graff D.W., Cascio W.E., Brackhan J.A., and Devlin R.B. Metal particulate matter components affect gene expression and beat frequency of neonatal rat ventricular myocytes. Environ Health Perspect 112 (2004) 792-798
8. Hesterberg III T.W., Bunn W.B., Chase G.R., Valberg P.A., Slavin T.J., Lapin C.A., et al. A critical assessment of studies on the carcinogenic potential of diesel exhaust. Crit Rev Toxicol 36 (2006) 727-776
9. Hirano S., Furuyama A., Koike E., and Kobayashi T. Oxidative-stress potency of organic extracts of diesel exhaust and urban fine particles in rat heart microvessel endothelial cells. Toxicology 187 (2003) 161-170
10. Holgate S.T., Sandstrom T., Frew A.J., Stenfors N., Nordenhall C., Salvi S., et al. Health effects of acute exposure to air pollution. Part I: Healthy and asthmatic subjects exposed to diesel exhaust. Res Rep Health Eff Inst 112 (2003) 1-30 (discussion 51-67)
11. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Vo. 46. Diesel and gasoline engine exhausts and some nitroarenes, 1989.
12. Kado NY, Kuzmicky PA. Bioassay analyses of particulate matter froma diesel bus engine using various biodiesel feedstock fuels. National Renewable Energy Laboratory Report NREL/SR-510-31463. Golden, CO, USA, 2003.
13. Madden M.C., Dailey L.A., Stonehuerner J.G., and Harris D.B. Responses of cultured human airway epithelial cells treated with diesel exhaust extracts will vary with the engine load. J Toxicol Environ Health Part A 66 (2003) 2281-2297
14. McDonald J.D., Harrod K.S., Seagrave J., Seilkop S.K., and Mauderly J.L. Effects of low sulfur fuel and a catalyzed particle trap on the composition and toxicity of diesel emissions. Environ Health Perspect 112 (2004) 1307-1312
15. Mills N.L., Tornqvist H., Robinson S.D., Gonzalez M., Darnley K., MacNee W., et al. Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation 20 (2005) 3930-3936
16. Nemmar A., Hoet P.H., Dinsdale D., Vermylen J., Hoylaerts M.F., and Nemery B. Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 107 (2003) 1202-1208
17. Nightingale J.A., Maggs R., Cullinan P., Donnelly L.E., Rogers D.F., Kinnersley R., et al. Airway inflammation after controlled exposure to diesel exhaust particulates. Am J Respir Crit Care Med 162 (2000) 161-166
18. Okayama Y., Kuwahara M., Suzuki A.K., and Tsubone H. Role of reactive oxygen species on diesel exhaust particle-induced cytotoxicity in rat cardiac myocytes. J Toxicol Environ Health A 69 (2006) 1699-1710
19. Seagrave J., Dunaway S., McDonald J.D., Mauderly J.L., Hayden P., and Stidley C. Responses of differentiated primary human lung epithelial cells to exposure to diesel exhaust at an air-liquid interface. Exp Lung Res 33 (2007) 27-51
20. Stenfors N., Nordenhall C., Salvi S.S., Mudway I., Soderberg M., Blomberg A., et al. Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel. Eur Respir J 23 (2004) 82-86
21. Swanson K.J., Madden M.C., and Ghio A.J. Biodiesel exhaust: the need for health effects research. Environ Health Perspect 115 (2007) 496-499
22. Ullman T., Smith L., Anthony J., Slowdowske W., Trestall B., Bunn W., et al. Comparison of exhaust emissions, including toxic air contaminants, from school buses in compressed natural gas, low emitting diesel, and conventional diesel engine configurations. SAE 003-01-1381 (2003), Society of Automotive Engineers, Warrendale, PA
23. United States Environmental Protection Agency. Control of air pollution from new motor vehicles: heavy-duty engine and vehicle standards and highway diesel fuel sulfur control requirements. 40 CFR Parts 69, 80, and 86, vol. 66, no. 12. Federal Register: January 18, 2001.
24. United States Environmental Protection Agency.. Health assessment document for diesel exhaust. EPA/600/8-90/057F. Washington, DC, USA, 2002.
25. United States Environmental Protection Agency. Air quality criteria for particulate matter (October 2004). 600/P-99/002aF-bF, 2004. Washington, DC, USA, 2004a.
26. United States Environmental Protection Agency. Control of emissions of air pollution from nonroad diesel engines and fuel. 40 CFR Parts 9, 69, 80, 86, 89, 94, 1039, 1048, 1051, 1065, and 1068, Vol. 69, no. 124. Federal Register: June 29, 2004.
27. Wan J., and Diaz-Sanchez D. Phase II enzymes induction blocks the enhanced IgE production in B cells by diesel exhaust particles. J Immunol 177 (2006) 3477-3483
28. Watanabe N. Decreased number of sperms and Sertoli cells in mature rats exposed to diesel exhaust as fetuses. Toxicol Lett 155 (2005) 51-58
29. Xiao G.G., Wang M., Li N., Loo J.A., and Nel A.E. Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line. J Biol Chem 278 (2003) 50781-50790
30. Zeiger E. Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: premises, promises, and performance. Regul Toxicol Pharmacol 28 (1998) 85-95