Pr-lynx1, a modulator of nicotinic acetylcholine receptors in the insect

Molecular and Cellular Neuroscience

Volumn 38, Issue 2, 2008, Pages 224-235

  Choo, Young Moo ^a   Lee, Byung Hwan ^b   Lee, Kwang Sik ^a   Kim, Bo Yeon ^a   Li, Jianhong ^c   Kim, Jong Gill ^d   Lee, Jae Heon ^a   Sohn, Hung Dae ^a   Nah, Seung Yeol ^b   Jin, Byung Rae ^a  

^a Dong A University   (South Korea)

^b Konkuk University   (South Korea)

^c HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^d National Institute of Animal Science   (South Korea)

Author keywords

insect; Ly 6 neurotoxin superfamily; nAChR modulator; Nicotinic acetylcholine receptors (nAChRs)

Indexed keywords

AMINO ACID; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; INSECT PROTEIN; NICOTINIC RECEPTOR; PROTEIN PR LYNX1;

ARTICLE; AVIAN STOMACH; BACULOVIRUS; BRAIN TISSUE; CELL SURFACE; CONTROLLED STUDY; DNA LIBRARY; EPIDERMIS; FIREFLY; GANGLION; GENE IDENTIFICATION; GENE ISOLATION; GENE STRUCTURE; IMMUNOREACTIVITY; INSECT; LEG MUSCLE; MOLECULAR CLONING; MUSCLE TISSUE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; CELL LINE; CLONING, MOLECULAR; FIREFLIES; HUMANS; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS; SNAILS; XENOPUS LAEVIS;

HEXAPODA; PYROCOELIA RUFA;

EID: 44649162467     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2008.02.011     Document Type: Article

References (62)

1. Abrous D.N., Adriani W., Montaron M.F., Aurousseau C., Rougon G., Le Moal M., and Piazza P.V. Nicotine self-administration impairs hippocampal plasticity. J. Neurosci. 22 (2002) 3656-3662
2. Alexander S., Mathie A., and Peters J. Trends in Pharmacological Science 2001 Nomenclature Supplement. 12th ed (2001), Elsevier, London 7-12
3. Bae J.S., Kim I., Sohn H.D., and Jin B.R. The mitochondrial genome of the firefly, Pyrocoelia rufa: complete DNA sequence, genome organization, and phylogenetic analysis with other insects. Mol. Phylogenet. Evol. 32 (2004) 978-985
4. Bass C., Lansdell S.J., Millar N.S., Schroeder I., Turberg A., Field L.M., and Williamson M.S. Molecular characterization of nicotinic acetylcholine receptor subunits from the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae). Insect Biochem. Mol. Biol. 36 (2006) 86-96
5. Battaglioli E., Gotti C., Terzano S., Flora A., Clementi F., and Fornasari D. Expression and transcriptional regulation of the human alpha 3 neuronal nicotinic receptors subunit in T lymphocyte cell lines. J. Neurochem. 71 (1998) 1261-1270
6. Broide R.S., Salas R., Ji D., Paylor R., Patrick J.W., Dani J.A., and De Biasi M. Increased sensitivity to nicotine-induced seizures in mice expressing the L250T α7 nicotinic acetylcholine receptor mutation. Mol. Pharmacol. 61 (2002) 695-705
7. Chang L.S., Lin J., Chou Y.C., and Hong E. Genomic structures of cardiotoxin 4 and cobratoxin from Naja naja atra (Taiwan cobra). Biochem. Biophys. Res. Commun. 239 (1997) 756-762
8. Changeux J.P., and Edelstein S.J. Allosteric receptors after 30 years. Neuron 21 (1998) 959-980
9. Chimienti F., Hogg R.C., Plantard L., Lehmann C., Brakch N., Fischer J., Huber M., Bertrand D., and Hohl D. Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Hum. Mol. Genet. 12 (2003) 3017-3024
10. Chini B., Clementi F., Hukovic N., and Sher E. Neuronal-type α-bungarotoxin receptors and the α5-nicotinic receptor subunit gene are expressed in neuronal and non-neuronal human cell lines. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 1572-1576
11. Choi S., Jung S.Y., Lee J.H., Sala F., Criado M., Mulet J., Valor L.M., Sala S., Engel A.G., and Nah S.Y. Effects of ginsenosides, active components of ginseng, on nicotinic acetylcholine receptors expressed in Xenopus oocytes. Eur. J. Pharmacol. 442 (2002) 37-45
12. Chou J.H., Bargmann C.I., and Sengupta P. The Caenorhabditis elegans odr-2 gene encodes a novel Ly-6-related protein required for olfaction. Genetics 157 (2001) 211-224
13. Damaj M.I., Glassco W., Dukat M., and Martin B.R. Pharmacological characterization of nicotine-induced seizures in mice. J. Pharmacol. Exp. Ther. 291 (1999) 1284-1291
14. Dani J.A. Overview of nicotinic receptors and their roles in the central nervous system. Biol. Psychiatry 49 (2001) 166-174
15. Dani J.A., Radcliffe K.A., and Pidoplichko V.I. Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas. Eur. J. Pharmacol. 393 (2000) 31-38
16. Dessaud E., Salaün D., Gayet O., Chabbert M., and deLapeyrière O. Identification of lynx2, a novel member of the ly-6/neurotoxin superfamily, expressed in neuronal subpopulations during mouse development. Mol. Cell. Neurosci. 31 (2006) 232-242
17. Eastham H.M., Lind R.J., Clarke B.S., Towner P., Reynolds S.E., Wolstenholme A.J., and Wonnacott S. Characterization of a nicotinic acetylcholine receptor from the insect Manduca sexta. Eur. J. Neurosci. 10 (1998) 879-889
18. Fleming T.J., OhUigin C., and Malek T.R. Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to α-bungarotoxin and other neurotoxins. J. Immunol. 150 (1993) 5379-5390
19. Fletcher C.H., Lachmann P.J., and Neuhaus D. Structure of a soluble form of the human complement regulatory protein CD59. Structure 2 (1994) 185-199
20. Fonck C., Nashmi R., Deshpande P., Damaj M.I., Marks M.J., Riedel A., Schwarz J., Collins A.C., Labarca C., and Lester H.A. Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive α4 nicotinic receptors. J. Neurosci. 23 (2003) 2582-2590
21. Gao J.R., Deacutis J.M., and Scott J.G. The nicotinic acetylcholine receptor subunit Mdα6 from Musca domestica is diversified via post-transcriptional modification. Insect Mol. Biol. 16 (2007) 325-334
22. Gao J.R., Deacutis J.M., and Scott J.G. Characterization of the nicotinic acetylcholine receptor subunit gene Mdα2 from the house fly, Musca domestica. Arch. Insect Biochem. Physiol. 64 (2007) 30-42
23. Gotti C., Fornasari D., and Clementi F. Human neuronal nicotinic receptors. Prog. Neurobiol. 53 (1997) 199-237
24. Grando S.A., Horton R.M., Pereira E.F., Diethlem-Okita B.M., George P.M., Albuquerque E.X., and Conti Fine B.M. A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes. J. Invest. Dermatol. 105 (1995) 774-781
25. Ibanez-Tallon I., Miwa J.M., Wang H.L., Adams N.C., Crabtree G.W., Sine S.M., and Heintz N. Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron 33 (2002) 893-903
26. Ibanez-Tallon I., Wen H., Miwa J.M., Xing J., Tekinay A.B., Ono F., Brehm P., and Heintz N. Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron 43 (2004) 305-311
27. Je Y.H., Chang J.H., Choi J.Y., Roh J.Y., Jin B.R., O'Reilly D.R., and Kang S.K. A defective viral genome maintained in Escherichia coli for the generation of baculovirus expression vectors. Biotechnol. Lett. 23 (2001) 575-582
28. Jennings K.R., Brown D.G., and Wright Jr. D.P. Methyllycaconitine, a naturally occurring insecticide with a high affinity for the insect cholinergic receptor. Experimenta 42 (1986) 611-613
29. 3 action on ion channels. Mol. Cells 18 (2004) 383-389
30. Jones A.K., Grauso M., and Sattelle D.B. The nicotinic acetylcholine receptors gene family of the malaria mosquito, Anopheles gambiae. Genomics 85 (2005) 176-187
31. Kang S.K., Lee J.Y., Chung T.W., and Kim C.H. Overexpression of transglutaminase 2 accelerates the erythroid differentiation of human chronic myelogenous leukemia K562 cell line through PI3K/Akt signaling pathway. FEBS Lett. 577 (2004) 361-366
32. Kim J.G., Kim K.Y., Choi Y.C., Choi J.Y., Kim S.E., Jin B.R., Lee S.M., Lee J.E., Lee K.Y., and Lee S.H. Developmental characteristics and life history of the Korean native firefly, Pyrocoelia rufa. Int. J. Indust. Entomol. 6 (2003) 69-73
33. Lee K.S., Park H.J., Bae J.S., Goo T.W., Kim I., Sohn H.D., and Jin B.R. Molecular cloning and expression of a cDNA encoding the luciferase from the firefly, Pyrocoelia rufa. J. Biotechnol. 92 (2001) 9-19
34. Lind R.J., Clough M.S., Reynolds S.E., and Earley F.G.P. [3H]-Imidacloprid labels high and low affinity nicotinic acetylcholine receptor-like binding sites in the aphid Myzus persicae (Hemiptera: Aphididae). Pestic. Biochem. Physiol. 62 (1998) 3-14
35. Lindstrom J. Neuronal nicotinic acetylcholine receptors. In: Narahashi T. (Ed). Ion Channels vol. 4 (1996), Plenum, New York 377-450
36. Lindstrom J. Nicotinic acetylcholine receptors in health and disease. Mol. Neurobiol. 15 (1997) 193-222
37. Lindstrom J., Anand R., Peng X., Gerzanich V., Wang F., and Li Y. Neuronal nicotinic receptor subtypes. Ann. N. Y. Acad. Sci. 757 (1995) 100-116
38. Littleton T.J., and Ganetzky B. Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 26 (2000) 35-43
39. Liu Z.W., Williamson M.S., Lansdell S.J., Denholm I., Han Z.J., and Millar N.S. A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens (brown planthopper). Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 8420-8425
40. Lukas R.J., Changeux J.P., Le Novere N., Albuquerque E.X., Balfour D.J.K., Berg D.K., Bertrand D., Chiappinelli V.A., Clarke P.B.S., Collins A.C., Dani J.A., Grady S.R., Kellar K.J., Lindstrom J.M., Marks M.J., Quik M., Taylor P.W., and Wonnacott S. International union of pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacol. Rev. 51 (1999) 397-401
41. MacAllan D.R.E., Lunt G.G., Wonnacott S., Swanson K.L., Rapoport H., and Albuquerque E.X. Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems. FEBS Lett. 226 (1988) 357-363
42. Mansvelder H.D., and McGehee D.S. Long-term potentiation of excitatory inputs to brain reward areas by nicotine. Neuron 27 (2000) 349-357
43. Mann E.O., and Greenfield S.A. Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro. J. Physiol. 551 (2003) 539-550
44. Marshall J., Buckingham S.D., Shingai R., Lunt G.G., Goosey M.W., Darlison M.G., Sattelle D.B., and Barnard E.A. Sequencing and functional expression of a single alpha subunit of an insect nicotinic acetylcholine receptor. EMBO J. 9 (1990) 4391-4398
45. Matsuda K., Buckingham S.D., Kleier D., Rauh J.J., Grauso M., and Sattelle D.B. Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors. Trends Pharmacol. Sci. 22 (2001) 573-580
46. McGehee D.S., and Role L.W. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu. Rev. Physiol. 57 (1995) 521-546
47. Miwa J.M., Ibanez-Tallon I., Crabtree G.W., Sanchez R., Sali A., Role L.W., and Heintz N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron 23 (1999) 105-114
48. Miwa J.M., Stevens T.R., King S.L., Caldarone B.J., Ibanez-Tallon I., Xiao C., Fitzsimonds R.M., Pavlides C., Lester H.A., Picciotto M.R., and Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron 51 (2006) 587-600
49. Orr G.L., Orr N., and Hollingworth R.M. Localization and pharmacological characterization of nicotinic-cholinergic binding sites in cockroach brain using α- and neuronal bungarotoxin. Insect Biochem. 20 (1990) 557-566
50. Picciotto M.R., and Zoli M. Nicotinic receptors in aging and dementia. J. Neurobiol. 53 (2002) 641-655
51. Sala C., Kimura I., Santoro G., Kuimura M., and Fumagalli G. Expression of two neuronal nicotinic receptor subunits in innervated and denervated adult rat muscle. Neurosci. Lett. 214 (1996) 1-4
52. Sargent P.B. The diversity of neuronal nicotinic acetylcholine receptors. Annu. Rev. Neurosci. 16 (1993) 403-443
53. Sattelle D.B., Pinnock R.D., and Lummis S.C.R. Voltage-independent block of a neuronal nicotinic acetylcholine receptor by N-methyllycaconitine. J. Exp. Biol. 142 (1989) 215-224
54. 3 receptor-mediated response and trafficking by activation of protein kinase C. J. Biol. Chem. 278 (2003) 34150-34157
55. Thany S.H., Lenaers G., Crozatier M., Armengaud C., and Gauthier M. Identification and localization of the nicotinic acetylcholine receptor alpha3 mRNA in the brain of the honeybee, Apis mellifera. Insect Mol. Biol. 12 (2003) 255-262
56. Thany S.H., Crozatier M., Raymond-delpech V., Gauthier M., and Lenaers G. Apis alpha 2, Apis alpha 7-1 and Apis alpha 7-2: three new neuronal nicotinic acetylcholine receptor alpha-subunits in the honeybee brain. Gene 344 (2005) 125-132
57. Tomizawa M., and Casida J.E. Structure and diversity of insect nicotinic acetylcholine receptors. Pest Manag. Sci. 57 (2001) 914-922
58. Tomizawa M., and Casida J.E. Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptors. Annu. Rev. Entomol. 48 (2003) 339-364
59. Tsetlin V. Snake venom alpha-neurotoxins and other 'three-finger' proteins. Eur. J. Biochem. 264 (1999) 281-286
60. Udenfriend S., and Kodukula K. How glycosyl-phosphatidyl-inositol-anchored membrane proteins are made. Annu. Rev. Biochem. 64 (1995) 563-591
61. Wooltorton J.R., Pidoplichko V.I., Broide R.S., and Dani J.A. Differential desensitization and distribution of nicotinic acetylcholine receptor subtypes in midbrain dopamine areas. J. Neurosci. 23 (2003) 3176-3185
62. Xu W., Orr-Urtreger A., Nigro F., Gelber S., Sutcliffe C.B., Armstrong D., Patrick J., Role L., Beaudet A.L., and De Biasi M. Multiorgan autonomic dysfunction in mice lacking the β2 and the β4 subunits of neuronal acetylcholine receptors. J. Neurosci. 19 (1999) 9298-9305