메뉴 건너뛰기




Volumn 13, Issue 5, 2008, Pages 1156-1178

Prodrugs in cardiovascular therapy

Author keywords

Antiplatelet; Antithrombin; Cardiovascular disease; Drug eluting stents; Prodrug

Indexed keywords

PRODRUG;

EID: 44449162489     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules13051156     Document Type: Review
Times cited : (8)

References (79)
  • 1
    • 0001199533 scopus 로고
    • Chemical Aspects of Selective Toxicity
    • Albert, A. Chemical Aspects of Selective Toxicity. Nature 1958, 182, 421-423.
    • (1958) Nature , vol.182 , pp. 421-423
    • Albert, A.1
  • 5
    • 0037176941 scopus 로고    scopus 로고
    • Direct Thrombin Inhibitors in Acute Coronary Syndromes: Present and Future
    • Weitz, J.I.; Buller, H.R. Direct Thrombin Inhibitors in Acute Coronary Syndromes: Present and Future. Circulation 2002, 105, 1004-1011.
    • (2002) Circulation , vol.105 , pp. 1004-1011
    • Weitz, J.I.1    Buller, H.R.2
  • 6
    • 1842647532 scopus 로고    scopus 로고
    • Inhibition of thrombin-induced feedback activation of factor V: A potential pathway for inhibition of thrombin generation by melagatran
    • Boström, S.L.; Dagnelid, E.; Hansson, G.F.H.; Ulvinge, J.C. Inhibition of thrombin-induced feedback activation of factor V: a potential pathway for inhibition of thrombin generation by melagatran. Blood Coagul. Fibrinolysis 2004, 15, 25-30.
    • (2004) Blood Coagul. Fibrinolysis , vol.15 , pp. 25-30
    • Boström, S.L.1    Dagnelid, E.2    Hansson, G.F.H.3    Ulvinge, J.C.4
  • 9
    • 0013450925 scopus 로고    scopus 로고
    • Antithrombotic effects of the direct thrombin inhibitor BIBR953ZW and its orally active prodrug BIBR1048MS in a model of venous thrombosis in rabbits
    • Wienen, W.; Nar, H.; Ries, U.; Priepke, H.; Hauel, N.; Stassen, J. Antithrombotic effects of the direct thrombin inhibitor BIBR953ZW and its orally active prodrug BIBR1048MS in a model of venous thrombosis in rabbits. Thromb. Haemost. 2001, 79, 110-118.
    • (2001) Thromb. Haemost , vol.79 , pp. 110-118
    • Wienen, W.1    Nar, H.2    Ries, U.3    Priepke, H.4    Hauel, N.5    Stassen, J.6
  • 10
    • 0013360567 scopus 로고    scopus 로고
    • Effects of the direct thrombin inhibitor BIBR953ZW and its orally active prodrug BIBR1048MS on experimentally-induced clot formation and template bleeding time in rats
    • Wienen, W.; Nar, H.; Ries, U.J.; Priepke, H.W.M.; Hauel, N.H. Effects of the direct thrombin inhibitor BIBR953ZW and its orally active prodrug BIBR1048MS on experimentally-induced clot formation and template bleeding time in rats. Thromb. Haemost. 2001, (Suppl.), P761.
    • (2001) Thromb. Haemost , Issue.SUPPL.
    • Wienen, W.1    Nar, H.2    Ries, U.J.3    Priepke, H.W.M.4    Hauel, N.H.5
  • 11
    • 0141750717 scopus 로고    scopus 로고
    • Oral direct thrombin inhibitors in clinical development
    • Gustafsson, D. Oral direct thrombin inhibitors in clinical development. J. Intern. Med. 2003, 254, 322-334.
    • (2003) J. Intern. Med , vol.254 , pp. 322-334
    • Gustafsson, D.1
  • 12
    • 0027125530 scopus 로고
    • Mechanisma of Disease - The Pathogenesis of Coronary-Artery Disease and the Acute Coronary Syndromes
    • Fuster, V.; Badimon, L.; Badimon, J.; Chesebro, J. Mechanisma of Disease - The Pathogenesis of Coronary-Artery Disease and the Acute Coronary Syndromes. N. Engl. J. Med. 1992, 326, 242-250.
    • (1992) N. Engl. J. Med , vol.326 , pp. 242-250
    • Fuster, V.1    Badimon, L.2    Badimon, J.3    Chesebro, J.4
  • 13
    • 0029062761 scopus 로고
    • Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine
    • Lefkovits, J.; Plow, E.F.; Topol, E.J. Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine. N. Engl. J. Med. 1995, 332, 1553-1559.
    • (1995) N. Engl. J. Med , vol.332 , pp. 1553-1559
    • Lefkovits, J.1    Plow, E.F.2    Topol, E.J.3
  • 14
    • 0034651322 scopus 로고    scopus 로고
    • Synthetic Inhibitors of Platelet Glycoprotein IIb/IIIa in Clinical Development
    • Verstraete, M. Synthetic Inhibitors of Platelet Glycoprotein IIb/IIIa in Clinical Development. Circulation 2000, 101, e76-e80.
    • (2000) Circulation , vol.101
    • Verstraete, M.1
  • 15
    • 0342872079 scopus 로고    scopus 로고
    • Profound and Sustained Inhibition of Platelet Aggregation by Fradafiban, a Nonpeptide Platelet Glycoprotein IIb/IIIa Antagonist, and Its Orally Active Prodrug, Lefradafiban, in Men
    • Muller, T.H.; Weisenberger, H.; Brickl, R.; Narjes, H.; Himmelsbach, F.; Krause, J. Profound and Sustained Inhibition of Platelet Aggregation by Fradafiban, a Nonpeptide Platelet Glycoprotein IIb/IIIa Antagonist, and Its Orally Active Prodrug, Lefradafiban, in Men. Circulation 1997, 96, 1130-1138.
    • (1997) Circulation , vol.96 , pp. 1130-1138
    • Muller, T.H.1    Weisenberger, H.2    Brickl, R.3    Narjes, H.4    Himmelsbach, F.5    Krause, J.6
  • 17
    • 0038160845 scopus 로고    scopus 로고
    • Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy)
    • Serebruany, V.L.; Malinin, A.I.; O'Connor, C.M.; Gurbel, P.A. Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy). Am. Heart J. 2003, 146, 91-98.
    • (2003) Am. Heart J , vol.146 , pp. 91-98
    • Serebruany, V.L.1    Malinin, A.I.2    O'Connor, C.M.3    Gurbel, P.A.4
  • 18
    • 34147164522 scopus 로고    scopus 로고
    • Platelet GPIIb/IIIa antagonist, XV459, in heparin-induced thrombocytopenia
    • Mousa S.A.; Ahmad, S. Platelet GPIIb/IIIa antagonist, XV459, in heparin-induced thrombocytopenia. Am. J. Hematol. 2007, 82, 276-282.
    • (2007) Am. J. Hematol , vol.82 , pp. 276-282
    • Mousa, S.A.1    Ahmad, S.2
  • 19
    • 34447642317 scopus 로고    scopus 로고
    • Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist
    • Barrett, Y.C.; Ebling, W.; Pieniaszek, H.; Billheimer, J.; Seiffert, D. Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist. J. Pharm. Biomed. Anal. 2007, 44, 938-946.
    • (2007) J. Pharm. Biomed. Anal , vol.44 , pp. 938-946
    • Barrett, Y.C.1    Ebling, W.2    Pieniaszek, H.3    Billheimer, J.4    Seiffert, D.5
  • 20
    • 0021871456 scopus 로고
    • Acute coronary occlusion during percutaneous transluminal coronary angioplasty
    • Shiu, M.; Silverton, N.; Oakley, D.; Cumberland, D. Acute coronary occlusion during percutaneous transluminal coronary angioplasty. Br. Heart J. 1985, 54, 129-133.
    • (1985) Br. Heart J , vol.54 , pp. 129-133
    • Shiu, M.1    Silverton, N.2    Oakley, D.3    Cumberland, D.4
  • 22
    • 0028083293 scopus 로고
    • The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A
    • Savi, P.; Combalbert, J.; Gaich, C.; Rouchon, M.C.; Maffrand, J.P.; Berger, Y.; Herbert, J.M. The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A. Thromb. Haemost. 1994, 72, 313-317.
    • (1994) Thromb. Haemost , vol.72 , pp. 313-317
    • Savi, P.1    Combalbert, J.2    Gaich, C.3    Rouchon, M.C.4    Maffrand, J.P.5    Berger, Y.6    Herbert, J.M.7
  • 28
    • 0031797365 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonists in hypertension
    • Burnier, M.; Brunner, H.R. Angiotensin II receptor antagonists in hypertension. Kidney Int. 1998, 54, S107-S111.
    • (1998) Kidney Int , vol.54
    • Burnier, M.1    Brunner, H.R.2
  • 29
    • 0030032937 scopus 로고    scopus 로고
    • Direct selective blockade of the vascular angiotensin II receptors in therapy for hypertension and severe congestive heart failure
    • Awan, N.A.; Mason, D.T. Direct selective blockade of the vascular angiotensin II receptors in therapy for hypertension and severe congestive heart failure. Am. Heart J. 1996, 131, 177-185.
    • (1996) Am. Heart J , vol.131 , pp. 177-185
    • Awan, N.A.1    Mason, D.T.2
  • 30
    • 0029743723 scopus 로고    scopus 로고
    • A new class of antihypertensive therapy : Angiotensin II receptor antagonists
    • Ellis, M.L.; Patterson, J.H. A new class of antihypertensive therapy : Angiotensin II receptor antagonists. Pharmacotherapy 1996, 16, 849-860.
    • (1996) Pharmacotherapy , vol.16 , pp. 849-860
    • Ellis, M.L.1    Patterson, J.H.2
  • 31
    • 0029588499 scopus 로고
    • Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans
    • Lo, M.W.; Goldberg, M.R.; McCrea, J.B.; Lu, H.; Furtek, C.I.; Bjornsson, T.D. Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans. Clin. Pharmacol. Ther. 1995, 58, 641-649.
    • (1995) Clin. Pharmacol. Ther , vol.58 , pp. 641-649
    • Lo, M.W.1    Goldberg, M.R.2    McCrea, J.B.3    Lu, H.4    Furtek, C.I.5    Bjornsson, T.D.6
  • 32
    • 0033950686 scopus 로고    scopus 로고
    • Newly emerging pharmacologic differences in angiotensin II receptor blockers
    • Oparil, S. Newly emerging pharmacologic differences in angiotensin II receptor blockers. Am. J. Hypertens. 2000, 13, S18-S24.
    • (2000) Am. J. Hypertens , vol.13
    • Oparil, S.1
  • 33
    • 0027399837 scopus 로고
    • Study on pharmacokinetics of a new biliary excreted oral angiotensin converting enzyme inhibitor, temocapril (CS-622) in humans
    • Suzuki, H.; Kawaratani, T.; Shioya, H.; Uji, Y.; Saruta, T. Study on pharmacokinetics of a new biliary excreted oral angiotensin converting enzyme inhibitor, temocapril (CS-622) in humans. Biopharm. Drug Dispos. 1993, 14, 41-50.
    • (1993) Biopharm. Drug Dispos , vol.14 , pp. 41-50
    • Suzuki, H.1    Kawaratani, T.2    Shioya, H.3    Uji, Y.4    Saruta, T.5
  • 34
    • 6344233584 scopus 로고    scopus 로고
    • Pharmacological and Clinical Studies with Temocapril, an Angiotensin Converting Enzyme Inhibitor that is Excreted in the Bile
    • Yasunari, K.; Maeda, K.; Nakamura, M.; Watanabe, T.; Yoshikawa, J.; Asada, A. Pharmacological and Clinical Studies with Temocapril, an Angiotensin Converting Enzyme Inhibitor that is Excreted in the Bile. Cardiovasc. Drug Rev. 2004, 22, 189-198.
    • (2004) Cardiovasc. Drug Rev , vol.22 , pp. 189-198
    • Yasunari, K.1    Maeda, K.2    Nakamura, M.3    Watanabe, T.4    Yoshikawa, J.5    Asada, A.6
  • 35
    • 0036341147 scopus 로고    scopus 로고
    • Beneficial Effects of Combined Blockade of ACE and AT1 Receptor on Intimal Hyperplasia in Balloon-Injured Rat Artery
    • Kim, S.; Izumi, Y.; Izumiya, Y.; Zhan, Y.; Taniguchi, M.; Iwao, H. Beneficial Effects of Combined Blockade of ACE and AT1 Receptor on Intimal Hyperplasia in Balloon-Injured Rat Artery. Arterioscler. Thromb. Vasc. Biol. 2002, 22, 1299-1304.
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 1299-1304
    • Kim, S.1    Izumi, Y.2    Izumiya, Y.3    Zhan, Y.4    Taniguchi, M.5    Iwao, H.6
  • 37
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of Pulmonary Arterial Hypertension
    • Humbert, M.; Sitbon, O.; Simonneau, G. Treatment of Pulmonary Arterial Hypertension. N. Engl. J. Med. 2004, 351, 1425-1436.
    • (2004) N. Engl. J. Med , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 38
    • 0028815739 scopus 로고
    • Current approaches to the therapy of fibrotic diseases
    • Franklin, T.J. Current approaches to the therapy of fibrotic diseases. Biochem. Pharmacol. 1995, 49, 267-273.
    • (1995) Biochem. Pharmacol , vol.49 , pp. 267-273
    • Franklin, T.J.1
  • 41
    • 1542359471 scopus 로고    scopus 로고
    • Effects of conjugated oestrogen and droloxifene on the renin-angiotensin system, blood pressure and renal blood flow in postmenopausal women
    • Seely, E.W.; Brosnihan, K.B.; Jeunemaitre, X.; Okamura, K.; Williams, G.H.; Hollenberg, N.K.; Herrington, D.M. Effects of conjugated oestrogen and droloxifene on the renin-angiotensin system, blood pressure and renal blood flow in postmenopausal women. Clin. Endocrinol. 2004, 60, 315-321.
    • (2004) Clin. Endocrinol , vol.60 , pp. 315-321
    • Seely, E.W.1    Brosnihan, K.B.2    Jeunemaitre, X.3    Okamura, K.4    Williams, G.H.5    Hollenberg, N.K.6    Herrington, D.M.7
  • 42
    • 0027226143 scopus 로고    scopus 로고
    • Moncada, S.; Martin, J.; Higgs, A. Symposium on regression of atherosclerosis. Eur. J. Clin. Invest. 1993, 23, 385-398.
    • Moncada, S.; Martin, J.; Higgs, A. Symposium on regression of atherosclerosis. Eur. J. Clin. Invest. 1993, 23, 385-398.
  • 43
    • 20044373069 scopus 로고    scopus 로고
    • Brunner, H.; Cockcroft, J.; Deanfield, J.; Donald, A.; Ferrannini, E.; Halcox, J.; Kiowski, W.; Luscher, T.; Mancia, G.; Natali, A.; Oliver, J.; Pessina, A.; Rizzoni, D.; Rossi, G.; Salvetti, A.; Spieker, L.; Taddei, S.; Webb, D. Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension. J. Hypertens. 2005, 23, 233-246.
    • Brunner, H.; Cockcroft, J.; Deanfield, J.; Donald, A.; Ferrannini, E.; Halcox, J.; Kiowski, W.; Luscher, T.; Mancia, G.; Natali, A.; Oliver, J.; Pessina, A.; Rizzoni, D.; Rossi, G.; Salvetti, A.; Spieker, L.; Taddei, S.; Webb, D. Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension. J. Hypertens. 2005, 23, 233-246.
  • 44
    • 0037125379 scopus 로고    scopus 로고
    • Principal Results From the Women's Health Initiative Randomized Controlled Trial
    • Writing Group for the Women's Health Initiative Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women
    • Writing Group for the Women's Health Initiative Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial. J. Am. Med. Assoc. 2002, 288, 321-333.
    • (2002) J. Am. Med. Assoc , vol.288 , pp. 321-333
  • 45
    • 0036892157 scopus 로고    scopus 로고
    • Minireview: Estrogen and Mouse Models of Atherosclerosis
    • Hodgin, J.B.; Maeda, N. Minireview: Estrogen and Mouse Models of Atherosclerosis. Endocrinology 2002, 143, 4495-4501.
    • (2002) Endocrinology , vol.143 , pp. 4495-4501
    • Hodgin, J.B.1    Maeda, N.2
  • 46
    • 0035095739 scopus 로고    scopus 로고
    • Estradiol Metabolites Inhibit Endothelin Synthesis by an Estrogen Receptor-Independent Mechanism
    • Dubey, R.K.; Jackson, E.K.; Keller, P.J.; Imthurn, B.; Rosselli, M. Estradiol Metabolites Inhibit Endothelin Synthesis by an Estrogen Receptor-Independent Mechanism. Hypertension 2001, 37, 640-644.
    • (2001) Hypertension , vol.37 , pp. 640-644
    • Dubey, R.K.1    Jackson, E.K.2    Keller, P.J.3    Imthurn, B.4    Rosselli, M.5
  • 47
    • 33746794978 scopus 로고    scopus 로고
    • 2-Methoxyestradiol, an Estradiol Metabolite, Inhibits Neointima Formation and Smooth Muscle Cell Growth via Double Blockade of the Cell Cycle
    • Barchiesi, F.; Jackson, E. K.; Fingerle, J.; Gillespie, D. G.; Odermatt, B.; Dubey, R.K. 2-Methoxyestradiol, an Estradiol Metabolite, Inhibits Neointima Formation and Smooth Muscle Cell Growth via Double Blockade of the Cell Cycle. Circ. Res. 2006, 99, 266-274.
    • (2006) Circ. Res , vol.99 , pp. 266-274
    • Barchiesi, F.1    Jackson, E.K.2    Fingerle, J.3    Gillespie, D.G.4    Odermatt, B.5    Dubey, R.K.6
  • 49
    • 0034638620 scopus 로고    scopus 로고
    • Methoxyestradiols Mediate the Antimitogenic Effects of Estradiol on Vascular Smooth Muscle Cells via Estrogen Receptor-Independent Mechanisms
    • Dubey, R.K.; Gillespie, D.G.; Zacharia, L.C.; Rosselli, M.; Korzekwa, K.R.; Fingerle, J.; Jackson, E.K. Methoxyestradiols Mediate the Antimitogenic Effects of Estradiol on Vascular Smooth Muscle Cells via Estrogen Receptor-Independent Mechanisms. Biochem.Bioph. Res. Co. 2000, 278, 27-33.
    • (2000) Biochem.Bioph. Res. Co , vol.278 , pp. 27-33
    • Dubey, R.K.1    Gillespie, D.G.2    Zacharia, L.C.3    Rosselli, M.4    Korzekwa, K.R.5    Fingerle, J.6    Jackson, E.K.7
  • 50
    • 0346365090 scopus 로고    scopus 로고
    • Methoxyestradiols Mediate the Antimitogenic Effects of 17{beta}-Estradiol: Direct Evidence From Catechol-O- Methyltransferase-Knockout Mice
    • Zacharia, L.C.; Gogos, J.A.; Karayiorgou, M.; Jackson, E.K.; Gillespie, D.G.; Barchiesi, F.; Dubey, R.K. Methoxyestradiols Mediate the Antimitogenic Effects of 17{beta}-Estradiol: Direct Evidence From Catechol-O- Methyltransferase-Knockout Mice. Circulation 2003, 108, 2974-2978.
    • (2003) Circulation , vol.108 , pp. 2974-2978
    • Zacharia, L.C.1    Gogos, J.A.2    Karayiorgou, M.3    Jackson, E.K.4    Gillespie, D.G.5    Barchiesi, F.6    Dubey, R.K.7
  • 51
    • 0036839384 scopus 로고    scopus 로고
    • 2-Hydroxyestradiol Attenuates Renal Disease in Chronic Puromycin Aminonucleoside Nephropathy
    • Tofovic, S.P.; Dubey, R.; Salah, E.M.; Jackson, E.K. 2-Hydroxyestradiol Attenuates Renal Disease in Chronic Puromycin Aminonucleoside Nephropathy. J. Am. Soc. Nephrol. 2002, 13, 2737-2747.
    • (2002) J. Am. Soc. Nephrol , vol.13 , pp. 2737-2747
    • Tofovic, S.P.1    Dubey, R.2    Salah, E.M.3    Jackson, E.K.4
  • 52
    • 2442647112 scopus 로고    scopus 로고
    • Estradiol metabolites retard the progression of pulmonary hypertension- preclinical evidence for clinical development
    • Tofovic, S.P.; Maddy, H.; Salah, E.M.; Jackson, E.K.; Melhem, M. Estradiol metabolites retard the progression of pulmonary hypertension- preclinical evidence for clinical development. Hypertension 2003b, 42, 416.
    • (2003) Hypertension , vol.42 , pp. 416
    • Tofovic, S.P.1    Maddy, H.2    Salah, E.M.3    Jackson, E.K.4    Melhem, M.5
  • 53
    • 2442703499 scopus 로고    scopus 로고
    • Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic angiotensin II administration
    • Tofovic, S.P.; Maddy, H.; Jackson, E.K. Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic angiotensin II administration. Hypertension 2003a, 42, 414.
    • (2003) Hypertension , vol.42 , pp. 414
    • Tofovic, S.P.1    Maddy, H.2    Jackson, E.K.3
  • 54
    • 33746856223 scopus 로고    scopus 로고
    • Does 2-Methoxyestradiol Represent the New and Improved Hormone Replacement Therapy for Atherosclerosis?
    • Dantas, A.P.V.; Sandberg, K. Does 2-Methoxyestradiol Represent the New and Improved Hormone Replacement Therapy for Atherosclerosis? Circ. Res. 2006, 99, 234-237.
    • (2006) Circ. Res , vol.99 , pp. 234-237
    • Dantas, A.P.V.1    Sandberg, K.2
  • 55
    • 5444224883 scopus 로고    scopus 로고
    • Macromolecular prodrugs: XI. Synthesis and characterization of polymer-estradiol conjugate
    • Zovko, M.; Zorc, B.; Novak, P.; Tepes, P.; Cetina-Cizmek, B.; Horvat, M. Macromolecular prodrugs: XI. Synthesis and characterization of polymer-estradiol conjugate. Int. J. Pharm. 2004, 285, 35-41.
    • (2004) Int. J. Pharm , vol.285 , pp. 35-41
    • Zovko, M.1    Zorc, B.2    Novak, P.3    Tepes, P.4    Cetina-Cizmek, B.5    Horvat, M.6
  • 56
    • 27844607407 scopus 로고    scopus 로고
    • Local delivery of 17 beta -estradiol improves reendothelialization and decreases inflammation after coronary stenting in a porcine model
    • Chandrasekar, B.; Sirois, M.G.; Geoffroy, P.; Lauzier, D.; Nattel, S.; Tanguay, J. F. Local delivery of 17 beta -estradiol improves reendothelialization and decreases inflammation after coronary stenting in a porcine model. Thromb. Haemost. 2005, 94, 1042-1047.
    • (2005) Thromb. Haemost , vol.94 , pp. 1042-1047
    • Chandrasekar, B.1    Sirois, M.G.2    Geoffroy, P.3    Lauzier, D.4    Nattel, S.5    Tanguay, J.F.6
  • 57
    • 1642285882 scopus 로고    scopus 로고
    • Enzymatic Release of Antitumor Ether Lipids by Specific Phospholipase A2 Activation of Liposome-Forming Prodrugs
    • Andresen, T.L.; Davidsen, J.; Begtrup, M.; Mouritsen, O.G.; Jorgensen, K. Enzymatic Release of Antitumor Ether Lipids by Specific Phospholipase A2 Activation of Liposome-Forming Prodrugs. J. Med. Chem. 2004, 47, 1694-1703.
    • (2004) J. Med. Chem , vol.47 , pp. 1694-1703
    • Andresen, T.L.1    Davidsen, J.2    Begtrup, M.3    Mouritsen, O.G.4    Jorgensen, K.5
  • 58
    • 34249079979 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Could they help to improve the efficacy of pharmacologic treatments for brain tumors?
    • Brioschi, A.; Zenga, F.; Zara, G.; Gasco, M.; Ducati, A.; Mauro, A. Solid lipid nanoparticles: could they help to improve the efficacy of pharmacologic treatments for brain tumors? Neurol. Res. 2007, 29, 324-330.
    • (2007) Neurol. Res , vol.29 , pp. 324-330
    • Brioschi, A.1    Zenga, F.2    Zara, G.3    Gasco, M.4    Ducati, A.5    Mauro, A.6
  • 59
    • 34447132890 scopus 로고    scopus 로고
    • Adipose Tissue-Derived Human Mesenchymal Stem Cells Mediated Prodrug Cancer Gene Therapy
    • Kucerova, L.; Altanerova, V.; Matuskova, M.; Tyciakova, S.; Altaner, C. Adipose Tissue-Derived Human Mesenchymal Stem Cells Mediated Prodrug Cancer Gene Therapy. Cancer Res. 2007, 67, 6304-6313.
    • (2007) Cancer Res , vol.67 , pp. 6304-6313
    • Kucerova, L.1    Altanerova, V.2    Matuskova, M.3    Tyciakova, S.4    Altaner, C.5
  • 60
    • 0031558240 scopus 로고    scopus 로고
    • Antibody-directed enzyme prodrug therapy (ADEPT): A review
    • Niculescu-Duvaz, I.; Springer, C. J. Antibody-directed enzyme prodrug therapy (ADEPT): a review. Adv. Drug Deliv. Rev. 1997, 26, 151-172.
    • (1997) Adv. Drug Deliv. Rev , vol.26 , pp. 151-172
    • Niculescu-Duvaz, I.1    Springer, C.J.2
  • 61
    • 0028592664 scopus 로고
    • Antibody directed enzyme prodrug therapy (ADEPT): A review of some theoretical, experimental and clinical aspects
    • Bagshawe, K.D.; Sharma, S.K.; Springer, C.J.; Rogers, G.T. Antibody directed enzyme prodrug therapy (ADEPT): A review of some theoretical, experimental and clinical aspects. Ann. Oncol. 1994, 5, 879-891.
    • (1994) Ann. Oncol , vol.5 , pp. 879-891
    • Bagshawe, K.D.1    Sharma, S.K.2    Springer, C.J.3    Rogers, G.T.4
  • 62
    • 0030445930 scopus 로고    scopus 로고
    • Prodrugs of thymidylate synthase inhibitors: Potential for antibody directed enzyme prodrug therapy (ADEPT)
    • Springer, C.; Bavetsias, V.; Jackman, A.; Boyle, F.; Marshall, D.; Pedely, R.; Bisset, G. Prodrugs of thymidylate synthase inhibitors: potential for antibody directed enzyme prodrug therapy (ADEPT). Anti-Cancer Drug Des. 1996, 11, 625-636.
    • (1996) Anti-Cancer Drug Des , vol.11 , pp. 625-636
    • Springer, C.1    Bavetsias, V.2    Jackman, A.3    Boyle, F.4    Marshall, D.5    Pedely, R.6    Bisset, G.7
  • 63
    • 0028694296 scopus 로고
    • Antibody-directed enzyme prodrug therapy (ADEPT). A three-phase study in ovarian tumor xenografts
    • Sharma, S.; Boden, J.; Springer, C.; Burke P.J.; Bagshawe, K. Antibody-directed enzyme prodrug therapy (ADEPT). A three-phase study in ovarian tumor xenografts. Cell Biophys. 1994, 24-25, 219-228.
    • (1994) Cell Biophys , vol.24-25 , pp. 219-228
    • Sharma, S.1    Boden, J.2    Springer, C.3    Burke, P.J.4    Bagshawe, K.5
  • 64
    • 0035858295 scopus 로고    scopus 로고
    • ATTEMPTS: A heparin/protamine-based prodrug approach for delivery of thrombolytic drugs
    • Liang, J.F.; Park, Y.J.; Song, H.; Li, Y.T.; Yang, V. ATTEMPTS: A heparin/protamine-based prodrug approach for delivery of thrombolytic drugs. J. Control. Release 2001, 72, 145-156.
    • (2001) J. Control. Release , vol.72 , pp. 145-156
    • Liang, J.F.1    Park, Y.J.2    Song, H.3    Li, Y.T.4    Yang, V.5
  • 66
    • 0037428958 scopus 로고    scopus 로고
    • ATTEMPTS: A heparin/protamine-based triggered release system for the delivery of enzyme drugs without associated side-effects
    • Park, Y.J.; Liang, J.F.; Song, H.; Li, Y.T.; Naik, S.; Yang, V.C. ATTEMPTS: a heparin/protamine-based triggered release system for the delivery of enzyme drugs without associated side-effects. Adv. Drug Deliv. Rev. 2003, 55, 251-265.
    • (2003) Adv. Drug Deliv. Rev , vol.55 , pp. 251-265
    • Park, Y.J.1    Liang, J.F.2    Song, H.3    Li, Y.T.4    Naik, S.5    Yang, V.C.6
  • 67
    • 0030588310 scopus 로고    scopus 로고
    • Multiple Alternating Molecular Layers of Albumin and Heparin on Solid Surfaces
    • Brynda, E.; Houska, M. Multiple Alternating Molecular Layers of Albumin and Heparin on Solid Surfaces. J. Colloid Interface Sci. 1996, 183, 18-25.
    • (1996) J. Colloid Interface Sci , vol.183 , pp. 18-25
    • Brynda, E.1    Houska, M.2
  • 68
    • 0031569785 scopus 로고    scopus 로고
    • Interactions of Proteins with Polyelectrolytes at Solid/Liquid Interfaces: Sequential Adsorption of Albumin and Heparin
    • Houska, M.; Brynda, E. Interactions of Proteins with Polyelectrolytes at Solid/Liquid Interfaces: Sequential Adsorption of Albumin and Heparin. J. Colloid Interface Sci. 1997, 188, 243-250
    • (1997) J. Colloid Interface Sci , vol.188 , pp. 243-250
    • Houska, M.1    Brynda, E.2
  • 69
    • 4143143210 scopus 로고    scopus 로고
    • Construction of albumin multilayer coating onto plasma treated poly(vinyl chloride) via electrostatic self-assembly
    • Jian, J.; Qinggang, T.; Jiacong, S. Construction of albumin multilayer coating onto plasma treated poly(vinyl chloride) via electrostatic self-assembly. Polym. Advanc. Technol. 2004, 15, 490-494.
    • (2004) Polym. Advanc. Technol , vol.15 , pp. 490-494
    • Jian, J.1    Qinggang, T.2    Jiacong, S.3
  • 70
    • 1642271404 scopus 로고    scopus 로고
    • Fabrication of alternating polycation and albumin multilayer coating onto stainless steel by electrostatic layer-by-layer adsorption
    • Ji, J.; Tan, Q.; Fan, D.Z.; Sun, F.Y.; Barbosa, M.A.; Shen, J. Fabrication of alternating polycation and albumin multilayer coating onto stainless steel by electrostatic layer-by-layer adsorption. Colloid. Surface. B. 2004, 34, 185-190.
    • (2004) Colloid. Surface. B , vol.34 , pp. 185-190
    • Ji, J.1    Tan, Q.2    Fan, D.Z.3    Sun, F.Y.4    Barbosa, M.A.5    Shen, J.6
  • 71
    • 22544443664 scopus 로고    scopus 로고
    • Construction of anti-adhesive and antibacterial multilayer films via layer-by-layer assembly of heparin and chitosan
    • Fu, J.; Ji, J.; Yuan, W.; Shen, J. Construction of anti-adhesive and antibacterial multilayer films via layer-by-layer assembly of heparin and chitosan. Biomaterials 2005, 26, 6684-6692.
    • (2005) Biomaterials , vol.26 , pp. 6684-6692
    • Fu, J.1    Ji, J.2    Yuan, W.3    Shen, J.4
  • 72
    • 0041386468 scopus 로고    scopus 로고
    • Constructing thromboresistant surface on biomedical stainless steel via layer-by-layer deposition anticoagulant
    • Tan, Q.; Ji, J.; Barbosa, M.A.; Fonseca, C.; Shen, J. Constructing thromboresistant surface on biomedical stainless steel via layer-by-layer deposition anticoagulant. Biomaterials 2003, 24, 4699.
    • (2003) Biomaterials , vol.24 , pp. 4699
    • Tan, Q.1    Ji, J.2    Barbosa, M.A.3    Fonseca, C.4    Shen, J.5
  • 73
    • 0036057106 scopus 로고    scopus 로고
    • Alternating Bioactivity of Polymeric Layer-by-Layer Assemblies: Anticoagulation vs Procoagulation of Human Blood
    • Serizawa, T.; Yamaguchi, M.; Akashi, M. Alternating Bioactivity of Polymeric Layer-by-Layer Assemblies: Anticoagulation vs Procoagulation of Human Blood. Biomacromolecules 2002, 3, 724-731.
    • (2002) Biomacromolecules , vol.3 , pp. 724-731
    • Serizawa, T.1    Yamaguchi, M.2    Akashi, M.3
  • 74
    • 0037883468 scopus 로고    scopus 로고
    • Layer-by-Layer Assembly on Hydrogel Surfaces and Control of Human Whole Blood Coagulation
    • Sakaguchi, H.; Serizawa, T.; Akashi, M. Layer-by-Layer Assembly on Hydrogel Surfaces and Control of Human Whole Blood Coagulation. Chem. Lett. 2003, 32, 174-175.
    • (2003) Chem. Lett , vol.32 , pp. 174-175
    • Sakaguchi, H.1    Serizawa, T.2    Akashi, M.3
  • 75
    • 20444454314 scopus 로고    scopus 로고
    • Polysaccharide-protein surface modification of titanium via a layer-by-layer technique: Characterization and cell behaviour aspects
    • Cai, K.; Rechtenbach, A.; Hao, J.; Bossert, J.; Jandt, K.D. Polysaccharide-protein surface modification of titanium via a layer-by-layer technique: Characterization and cell behaviour aspects. Biomaterials 2005, 26, 5960-5971.
    • (2005) Biomaterials , vol.26 , pp. 5960-5971
    • Cai, K.1    Rechtenbach, A.2    Hao, J.3    Bossert, J.4    Jandt, K.D.5
  • 76
    • 0345688797 scopus 로고    scopus 로고
    • Bioactive Coatings of Endovascular Stents Based on Polyelectrolyte Multilayers
    • Thierry, B.; Winnik, F.M.; Merhi, Y.; Silver, J.; Tabrizian, M. Bioactive Coatings of Endovascular Stents Based on Polyelectrolyte Multilayers. Biomacromolecules 2003, 4, 1564-1571.
    • (2003) Biomacromolecules , vol.4 , pp. 1564-1571
    • Thierry, B.1    Winnik, F.M.2    Merhi, Y.3    Silver, J.4    Tabrizian, M.5
  • 77
    • 0038208277 scopus 로고    scopus 로고
    • Nanocoatings onto Arteries via Layer-by-Layer Deposition: Toward the in Vivo Repair of Damaged Blood Vessels
    • Thierry, B.; Winnik, F.M.; Merhi, Y.; Tabrizian, M. Nanocoatings onto Arteries via Layer-by-Layer Deposition: Toward the in Vivo Repair of Damaged Blood Vessels. J. Am. Chem. Soc. 2003, 125, 7494-7495.
    • (2003) J. Am. Chem. Soc , vol.125 , pp. 7494-7495
    • Thierry, B.1    Winnik, F.M.2    Merhi, Y.3    Tabrizian, M.4
  • 78
    • 13644257605 scopus 로고    scopus 로고
    • Delivery Platform for Hydrophobic Drugs: Prodrug Approach Combined with Self-Assembled Multilayers
    • Thierry, B.; Kujawa, P.; Tkaczyk, C.; Winnik, F.M.; Bilodeau, L.; Tabrizian, M. Delivery Platform for Hydrophobic Drugs: Prodrug Approach Combined with Self-Assembled Multilayers. J. Am. Chem. Soc. 2005, 127, 1626-1627.
    • (2005) J. Am. Chem. Soc , vol.127 , pp. 1626-1627
    • Thierry, B.1    Kujawa, P.2    Tkaczyk, C.3    Winnik, F.M.4    Bilodeau, L.5    Tabrizian, M.6
  • 79
    • 0032693599 scopus 로고    scopus 로고
    • Atherosclerosis is an inflammatory disease
    • Ross, R. Atherosclerosis is an inflammatory disease. Am. Heart J. 1999, 138, S419-S420.
    • (1999) Am. Heart J , vol.138
    • Ross, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.