[11C]AZ10419369: A selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain

NeuroImage

Volumn 41, Issue 3, 2008, Pages 1075-1085

  Pierson, M Edward ^b   Andersson, Jan ^a   Nyberg, Svante ^c   McCarthy, Dennis J ^b   Finnema, Sjoerd J ^a   Varnäs, Katarina ^a   Takano, Akihiro ^a   Karlsson, Per ^a   Gulyás, Balázs ^a   Medd, Amy M ^b   Lee, Chi Ming ^b   Powell, Mark E ^b   Heys, J Richard ^b   Potts, William ^b   Seneca, Nicholas ^a,d   Mrzljak, Ladislav ^b   Farde, Lars ^a,e   Halldin, Christer ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ASTRAZENECA   (United Kingdom)

^c ASTRAZENECA R AND D   (Sweden)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^e CNSPain Discovery   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYL 8 (4 METHYLPIPERAZIN 1 YL) 4 OXO 4H CHROMENE 2 CARBOXYLIC ACID ( 4 MORPHOLIN 4 YL PHENYL)AMIDE; AZ 10419369; CARBON 11; METHYL TRIFLATE C 11; RADIOLIGAND; SEROTONIN 1B RECEPTOR; TRITIUM; 5 METHYL 8 (4 METHYL PIPERAZIN 1 YL) 4 OXO 4H CHROMENE 2 CARBOXYLIC ACID (4 MORPHOLIN 4 YL PHENYL)AMIDE; 5-METHYL-8-(4-METHYL-PIPERAZIN-1-YL)-4-OXO-4H-CHROMENE-2-CARBOXYLIC ACID (4-MORPHOLIN-4-YL-PHENYL)AMIDE; BENZOPYRAN DERIVATIVE; CARBON; DIAGNOSTIC AGENT; MORPHOLINE DERIVATIVE; PIPERAZINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CEREBELLUM; CONTROLLED STUDY; DEPRESSION; DIAGNOSTIC VALUE; DRUG BRAIN LEVEL; FEMALE; FRONTAL CORTEX; IN VIVO STUDY; ISOTOPE LABELING; LIGAND BINDING; MACACA; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIMATE; PRIORITY JOURNAL; RADIOACTIVITY; RADIOCHEMISTRY; RECEPTOR OCCUPANCY; TEMPORAL CORTEX; THALAMUS; ANIMAL; BRAIN; HUMAN; METABOLISM; SYNTHESIS;

ANIMALS; AUTORADIOGRAPHY; BENZOPYRANS; BRAIN; CARBON RADIOISOTOPES; FEMALE; HUMANS; MACACA; MORPHOLINES; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTOR, SEROTONIN, 5-HT1B;

EID: 44449161928     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2008.02.063     Document Type: Article

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