Characterization of human serotonin 1D and 1B receptors using [3H]-GR-125743, a novel radiolabelled serotonin 5HT1D/1B receptor antagonist

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 356, Issue 3, 1997, Pages 328-334

  Domenech T ^a   Beleta, J ^a   Palacios, J M ^a  

^a Laboratorios Almirall SA ^*  (Spain)

Author keywords

H5 HT(1B) receptor; H5 HT(1D) receptor; Human; Radioligand binding; Substantia nigra

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 5 CARBAMOYLTRYPTAMINE; 5 METHOXYTRYPTAMINE; 5 METHYLAMINOSULFONYLMETHYL 3 (1 METHYL 2 PYRROLIDINYLMETHYL) 1H INDOLE; GUANOSINE TRIPHOSPHATE; KETANSERIN; METERGOLINE; METITEPINE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 3 METHYL 4 (4 PYRIDYL)BENZAMIDE; NARATRIPTAN; RADIOLIGAND; RECEPTOR SUBTYPE; RITANSERIN; SEROTONIN; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D ANTAGONIST; SEROTONIN 1D RECEPTOR; SEROTONIN 5 O CARBOXYMETHYLGLYCYLTYROSINAMIDE; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR AFFECTING AGENT; SUMATRIPTAN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BINDING COMPETITION; BRAIN MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SPECIFICITY; FEMALE; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOLECULAR CLONING; RECEPTOR AFFINITY; REGRESSION ANALYSIS; SUBSTANTIA NIGRA;

BENZAMIDES; BINDING, COMPETITIVE; GENE EXPRESSION; HELA CELLS; HUMANS; KINETICS; LIGANDS; PYRIDINES; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT1D; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SUBSTANTIA NIGRA; TRITIUM;

EID: 0030921785     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005058     Document Type: Article

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