Conserved mycobacterial lipoglycoproteins activate TLR2 but also require glycosylation for MHC class II-restricted T cell activation

Journal of Immunology

Volumn 180, Issue 9, 2008, Pages 5833-5842

  Sieling, Peter A ^a   Hill, Preston J ^b   Dobos, Karen M ^b   Brookman, Kerry ^b   Kuhlman, Andrew M ^a   Fabri, Mario ^a   Krutzik, Stephan R ^a   Rea, Thomas H ^c   Heaslip, Darragh G ^b   Belisle, John T ^b   Modlin, Robert L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA MANNOSIDASE; BACTERIAL PROTEIN; GLYCOLIPOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE ANTIGEN; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; CARBOHYDRATE; HLA ANTIGEN CLASS 2; LIPOPROTEIN; RECOMBINANT PROTEIN; TLR2 PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; ESCHERICHIA COLI; HUMAN; HUMAN TISSUE; MALE; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; T LYMPHOCYTE ACTIVATION; CHEMISTRY; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM; PHYSIOLOGY;

ALPHA-MANNOSIDASE; ANTIGENS, BACTERIAL; CARBOHYDRATES; CD4-POSITIVE T-LYMPHOCYTES; ESCHERICHIA COLI; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LIPOPROTEINS; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM; RECOMBINANT PROTEINS; TOLL-LIKE RECEPTOR 2;

EID: 44449103785     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.9.5833     Document Type: Article

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