Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 10, 2001, Pages 1329-1332

  Manfredini, Stefano ^a   Baraldi, Pier G ^a   Durini, Elisa ^a   Porcu, Luca ^a   Angusti, Angela ^a   Vertuani, Silvia ^a   Solaroli, Nicola ^a,b   De Clercq, Erik ^c   Karlsson, Anna ^b   Balzarini, Jan ^c  

^a UNIVERSITY OF FERRARA   (Italy)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ARABINOFURANOSYL NUCLEOSIDE; CYTOSOLIC THYMIDINE KINASE; DROSOPHILA MELANOGASTER DEOXYRIBONUCLEOSIDE KINASE; HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE; MITOCHONDRIAL THYMIDINE KINASE; NUCLEOSIDE DERIVATIVE; THYMIDINE KINASE; THYMIDINE KINASE INHIBITOR; UNCLASSIFIED DRUG; VARICELLA ZOSTER VIRUS THYMIDINE KINASE;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; MOLECULAR MODEL; NONHUMAN; REACTION ANALYSIS;

DROSOPHILA MELANOGASTER; HERPES; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 3; MELANOGASTER;

EID: 18844479887     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00207-4     Document Type: Article

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