Potential involvement of leptin in carcinogenesis of hepatocellular carcinoma

World Journal of Gastroenterology

Volumn 10, Issue 17, 2004, Pages 2478-2481

  Wang, Xiu Jie ^a   Yuan, Shu Lan ^a   Lu, Qing ^b   Lu, Yan Rong ^a   Zhang, Jie ^a   Liu, Yan ^b   Wang, Wen Dong ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; LEPTIN; LEPTIN RECEPTOR; CELL SURFACE RECEPTOR;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MALE; PROTEIN EXPRESSION; CELL DIVISION; DRUG EFFECT; GENETICS; IN VITRO STUDY; LIVER TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; TUMOR CELL LINE;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LEPTIN; LIVER NEOPLASMS; MALE; MIDDLE AGED; RECEPTORS, CELL SURFACE;

EID: 4444337948     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i17.2478     Document Type: Article

References (37)

1. Sierra-Honigmann MR, Nath AK, Murakami C, Garcia-Cardena G, Papapetropoulos A, Sessa WC, Madge LA, Schechner JS, Schwabb MB, Polverini PJ, Flores-Riveros JR. Biological action of leptin as an angiogenic factor. Science 1998; 281: 1683-1686
2. Somasundar P, Yu AK, Vona-Davis L, McFadden DW. Differential effects of leptin on cancer in vitro. J Surg Res 2003; 113: 50-55
3. Onuma M, Bub JD, Rummel TL, Iwamoto Y. Prostate cancer cell-adipocyte interaction: Leptin mediates androgen-independent prostate cancer cell proliferation through c-Jun NH2-terminal kinase. J Biol Chem 2003; 278: 42660-42667
4. Janeckova R. The role of leptin in human physiology and pathophysiology. Physiol Res 2001; 50: 443-459
5. Stephenson GD, Rose DP. Breast cancer and obesity: an update. Nutr Cancer 2003; 45: 1-16
6. Stattin P, Kaaks R, Johansson R, Gislefoss R, Soderberg S, Alfthan H, Stenman UH, Jellum E, Olsson T. Plasma leptin is not associated with prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2003; 12: 474-475
7. Catalano S, Marsico S, Giordano C, Mauro L, Rizza P, Panno ML, Ando S. Leptin enhances, via AP-1, expression of aromatase in the MCF-7 cell line. J Biol Chem 2003; 278: 28668-28676
8. Stattin P, Palmqvist R, Soderberg S, Biessy C, Ardnor B, Hallmans G, Kaaks R, Olsson T. Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden. Oncol Rep 2003; 10: 2015-2021
9. Hu X, Juneja SC, Maihle NJ, Cleary MP. Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst 2002; 94: 1704-1711
10. Chan TF, Su JH, Chung YF, Chang HL, Yuan SS. Decreased serum leptin levels in women with uterine leiomyomas. Acta Obstet Gynecol Scand 2003; 82: 173-176
11. Saglam K, Aydur E, Yilmaz M, Goktas S. Leptin influences cellular differentiation and progression in prostate cancer. J Urol 2003; 169: 1308-1311
12. Kote-Jarai Z, Singh R, Durocher F, Easton D, Edwards SM, Ardern-Jones A, Dearnaley DP, Houlston R, Kirby R, Eeles R. Association between leptin receptor gene polymorphisms and early-onset prostate cancer. BJU Int 2003; 92: 109-112
13. Petridou E, Belechri M, Dessypris N, Koukoulomatis P, Diakomanolis E, Spanos E, Trichopoulos D. Leptin and body mass index in relation to endometrial cancer risk. Ann Nutr Metab 2002; 46: 147-151
14. Coskun U, Gunel N, Toruner FB, Sancak B, Onuk E, Bayram O, Cengiz O, Yilmaz E, Elbeg S, Ozkan S. Serum leptin, prolactin and vascular endothelial growth factor (VEGF) levels in patients with breast cancer. Neoplasma 2003; 50: 41-46
15. Isono M, Inoue R, Kamida T, Kobayashi H, Matsuyama J. Significance of leptin expression in invasive potential of pituitary adenomas. Clin Neurol Neurosurg 2003; 105: 111-116
16. Okumura M, Yamamoto M, Sakuma H, Kojima T, Maruyama T, Jamali M, Cooper DR, Yasuda K. Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-alpha and PPAR expression. Biochim Biophys Acta 2002; 1592: 107-116
17. Dieudonne MN, Machinal-Quelin F, Serazin-Leroy V, Leneveu MC, Pecquery R, Giudicelli Y. Leptin mediates a proliferative response in human MCF7 breast cancer cells. Biochem Biophys Res Commun 2002; 293: 622-628
18. Laud K, Gourdou I, Pessemesse L, Peyrat JP, Djiane J. Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line. Mol Cell Endocrinol 2002; 188: 219-226
19. Bruserud O, Huang TS, Glenjen N, Gjertsen BT, Foss B. Leptin in human acute myelogenous leukemia: studies of in vivo levels and in vitro effects on native functional leukemia blasts. Haematologica 2002; 87: 584-595
20. Qian J, Feng GS, Vogl T. Combined interventional therapies of hepatocellular carcinoma. World J Gastroenterol 2003; 9: 1885-1891
21. Zhu AX. Hepatocellular carcinoma: are we making progress? Cancer Invest 2003; 21: 418-428
22. Nair S, Mason A, Eason J, Loss G, Perrillo RP. Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? Hepatology 2002; 36: 150-155
23. Roth MJ, Baer DJ, Albert PS, Castonguay TW, Dorgan JF, Dawsey SM, Brown ED, Hartman TJ, Campbell WS, Giffen CA, Judd JT, Taylor PR. Relationship between serum leptin levels and alcohol consumption in a controlled feeding and alcohol ingestion study. J Natl Cancer Inst 2003; 95: 1722-1725
24. Wang YY, Lin SY. Leptin in relation to hepatocellular carcinoma in patients with liver cirrhosis. Horm Res 2003; 60: 185-190
25. Lin SY, Wang YY, Sheu WH. Increased serum leptin concentrations correlate with soluble tumour necrosis factor receptor levels in patients with cirrhosis. Clin Endocrinol 2002; 57: 805-811
26. Testa R, Franceschini R, Giannini E, Cataldi A, Botta F, Fasoli A, Tenerelli P, Rolandi E, Barreca T. Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis. J Hepatol 2000; 33: 33-37
27. Comlekci A, Akpinar H, Yesil S, Okan I, Ellidokuz E, Okan A, Ersoz G, Tankurt E, Batur Y. Serum leptin levels in patients with liver cirrhosis and chronic viral hepatitis. Scand J Gastroenterol 2003; 38: 779-786
28. Greco AV, Mingrone G, Favuzzi A, Capristo E, Gniuli D, Addolorato G, Brunani A, Cavagnin F, Gasbarrini G. Serum leptin levels in post-hepatitis liver cirrhosis. J Hepatol 2000; 33: 38-42
29. Campillo B, Sherman E, Richardet JP, Bories PN. Serum leptin levels in alcoholic liver cirrhosis: relationship with gender, nutritional status, liver function and energy metabolism. Eur J Clin Nutr 2001; 53: 980-988
30. Serin E, Ozer B, Gumurdulu Y, Kayaselcuk F, Kul K, Boyacioglu S. Serum leptin level can be a negative marker of hepatocyte damage in nonalcoholic fatty liver. J Gastroenterol 2003; 38: 471-476
31. Somasundar P, Riggs D, Jackson B, Vona-Davis L, McFadden DW. Leptin stimulates esophageal adenocarcinoma growth by nonapoptotic mechanisms. Am J Surg 2003; 186: 575-578
32. Yang S, Lin HZ, Hwang J, Chacko VP, Diehl AM. Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition? Cancer Res 2001; 61: 5016-5023
33. Hardwick JC, Van Den Brink GR, Offerhaus GJ, Van Deventer SJ, Peppelenbosch MP. Leptin is a growth factor for colonic epithelial cells. Gastroenterology 2001; 121: 79-90
34. Saxena NK, Saliba G, Floyd JJ, Anania FA. Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells. J Cell Biochem 2003; 89: 311-320
35. Leclercq IA, Farrell GC, Schriemer R, Robertson GR. Leptin is essential for the hepatic fibrogenic response to chronic liver injury. J Hepatol 2002; 37: 206-213
36. Shimizu H, Kakizaki S, Tsuchiya T, Nagamine T, Takagi H, Takayama H, Kobayashi I, Mori M. An increase of circulating leptin in patients with liver cirrhosis. Int J Obes Relat Metab Disord 1998; 22: 1234-1238
37. Iversen PO, Drevon CA, Reseland JE. Prevention of leptin binding to its receptor suppresses rat leukemic cell growth by inhibiting angiogenesis. Blood 2002; 100: 4123-4128