Genetic isolates in Corsica (France): Linkage disequilibrium extension analysis on the Xq13 region

European Journal of Human Genetics

Volumn 12, Issue 8, 2004, Pages 613-619

  Latini, Veronica ^a   Sole, Gabriella ^a   Doratiotto, Silvia ^a   Poddie, Daniela ^a   Memmi, Marc ^b   Varesi, Laurent ^b   Vona, Giuseppe ^c   Cao, Antonio ^a   Ristaldi, Maria Serafina ^a  

^a CNR   (Italy)

^b Université de Corte   (France)

^c UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Corsica; Linkage disequilibrium extension; Sardinia; Subisolates

Indexed keywords

ALLELE; ARTICLE; CHROMOSOME XQ; CONTROLLED STUDY; FRANCE; GENE IDENTIFICATION; GENE ISOLATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HUMAN; MAJOR CLINICAL STUDY; POPULATION DISTRIBUTION; POPULATION GENETICS; POPULATION RESEARCH; PRIORITY JOURNAL; SOUTHERN EUROPE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ALLELES; CHROMOSOMES, HUMAN, X; FOUNDER EFFECT; FRANCE; GENETICS, POPULATION; GEOGRAPHY; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MICROSATELLITE REPEATS; VARIATION (GENETICS);

EID: 4444272354     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201205     Document Type: Article

References (40)

1. Laan M, Paabo S: Demographic history and LD in human population. Nat Genet 1997; 17: 435-438.
2. Zavattari P, Deidda E, Whalen M et al: Major factors influencing LD by analysis of different chromosome regions in distinct populations: demography, chromosome recombination frequency and selection. Hum Mol Genet 2000; 9: 2947-2957.
3. Varilo T, Laan M, Hovatta I, Wiebe V, Terwilliger JD, Peltonen L: Linkage disequilibrium in isolated populations: Finland and young sub-population of Kuusano. Eur J Hum Genet 2000; 8: 604-612.
4. Angius A, Melis MP, Morelli L et al: Archival, demographic and genetic studies define a Sardinian sub-isolate as a suitable model for mapping complex traits. Hum Genet 2001; 109: 198-209.
5. Angius A, Bebbere D, Petretto E et al: Not all isolates are equal: linkage disequilibrium analysis on Xq13.3 reveals different patterns in Sardinian sub-populations. Hum Genet 2002; 111: 9-15.
6. Kaessmann H, Zollner S, Gustaffson A et al: Extensive LD in small human populations in Eurasia. Am J Hum Genet 2002; 70: 673-685.
7. Katoh T, Mono S, Ikuta T et al: Genetic isolates in East Asia: a study of linkage disequilibrium in the X chromosome. Am J Hum Genet 2002; 71: 395-400.
8. Taillon-Miller P, Bauer-Sardina I, Saccone NL et al: Juxtaposed regions of extensive and minimal linkage disequilibrium in human Xq25 and Xq28. Nat Genet 2000; 25: 324-328.
9. Eaves IA, Merriman T, Barber RA et al: The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes. Nat Genet 2000; 25: 320-323.
10. Vona G, Memmì M, Varesi L, Mameli GE, Succa V: A study of several genetic markers in the Corsican population (France). Anthropol Anz 1995; 53: 125-132.
11. Varesi L, Vona G, Memmì M, Marongiu F, Ristaldi MS: β-Thalassemia mutations in Corsica. Hemoglobin 2000; 24: 239-244.
12. Vona G, Memmì M, Calò CM et al: Genetic structure of the Corsican population (France): a review; in: Research Signpost (eds): Recent Research Developments in Human Genetics: 2002, Vol 1, pp 147-164.
13. Grimaldi MC, Crouau-Roy B, Contu L, Amoros JP: Molecular variation of HLA class I genes in the corsican population: approach to its origin. Eur J Immunogenet 2002; 29: 101-107.
14. Vona G, Moral P, Memmì M, Ghiani ME, Varesi L: Genetic structure and affinities of the Corsican population (France): classical genetic markers analysis. Am J Hum Biol 2003; 15: 151-163.
15. Varesi L, Memmì M, Cristofari MC, Mameli GE, Calò MC, Vona G: Mitochondrial control-region sequence in the corsican population (France). Am J Hum Biol 2000; 12: 339-351.
16. Ranque J, Vicoli R, Silicati V et al: Le peuplement humain in Corse. Varietè des populations insulaires. Etude sèroantropologique. Bull Soc Corse Biol Hum 1961; 1: 115-168.
17. Cappello N, Rendine S, Griffo R et al: Genetic analysis of Sardinia I data on 12 polymorphisms in 21 linguistic domains. Ann Hum Genet 1996; 60: 125-141.
18. Vona G: The peopling of Sardinia (Italy): history and effects. Int J Anthropol 1997; 12: 71-87.
19. Calò CM, Vacca L, Vona G: Analysis of selected microsatellites in 4 regions of Corsica (Francia). Antropol Contemp 1999; 87-98, (Monografia).
20. Latini V, Vona G, Ristaldi MS et al: β-Globin cluster haplo-types in Corsica and Sardinia populations. Hum Biol 2003; 75: 855-871.
21. Slatkin M: Linkage disequilibrium in growing and stable populations. Genetics 1994; 137: 331-336.
22. Lautenberger JA, Stephens JC, O'Brien SJ, Smith MW: Significant admixture linkage disequilibrium across the FY locus in African Americans. Am J Hum Genet 2000; 66: 969-978.
23. Lewontin RC: The interaction of selection and linkage. General considerations; heterotic models. Genetics 1964; 49: 49-67.
24. Efron B, Tibshirani RJ: An Introduction to the Bootstrap. New York: Chapman & Hall; 1993.
25. Abecasis GR, Cookson WO: Gold - graphical overview of linkage disequilibrium. Bioinformatics 2000; 16: 182-183.
26. Raymond M, Rousset F: GENEPOP (version 1.2): population genetics software for exact tests and ecumenisms. J Hered 1995; 86: 248-249.
27. Raymond M, Rousset F: An exact test for population differentiation. Evolution 1995; 49: 1280-1283.
28. Reich DE, Cargill M, Bolk S et al: Linkage disequilibrium in the human genome. Nature 2001; 411: 199-204.
29. Mohlke KL, Lange EM, Valle TT et al: Linkage disequilibrium between microsatellite markers extends beyond 1 cM on chromosome 20 in Finns. Choice in mapping genes for complex diseases. Nat Genet 1999; 23: 394-404.
30. Ardlie KG, Kruglyak L, Seielstad M: Patterns of LD in the human genome. Nat Genet 2002; 3: 299-309.
31. Marrosu MG, Murru R, Murru MR et al: Dissection of the HLA association with multiple sclerosis in the founder isolate population of Sardinia. Hum Mol Genet 2001; 11: 1221-1226.
32. Sheffield VC, Stone EM, Carmi R: Use of isolated inbred human populations for identification of disease genes. TIG Rev 1998; 14: 391-396.
33. Wright AF, Carothers AD, Pirastu M: Population multiple sclerosis in the founder isolated population of Sardinia. Hum Mol Genet 2001; 10: 2907-2916.
34. Contu D, Morelli L, Zavattari P et al: Sex-related bias and exclusion mapping of the non recombinant portion of chromosome Y in human type 1 diabetes in the isolated founder population of Sardinia. Diabetes 2002; 51: 3573-3576.
35. Angius A, Petretto E, Maestrale GB et al: A new essential hypertension susceptibility locus on chromosome 2p24-p25, detected by genomewide search. Am J Hum Genet 2002; 71: 893-905.
36. Gianfrancesco F, Esposito T, Ombra MN et al: Identification of a novel gene and a common variant associated with uric acid nephrolithiasis in a Sardinian genetic isolate. Am J Hum Genet 2003; 72: 1479-1491.
37. Risch NJ: Searching for genetic determinants in the new millennium. Nature 2000; 405: 847-856.
38. Cardon LR, Bell JI: Association study designs for complex diseases. Nat Rev 2001; 2: 91-99.
39. Heath S, Robledo R, Beggs W: A novel approach to search for identity by descent in small samples of patients and controls from the same mendelian breeding unit: a pilot study on myopia. Hum Hered 2001; 52: 183-190.
40. Tishkoff SA, Williams SM: Genetic analysis of African populations: human evolution and complex disease. Nat Rev 2002; 3: 611-621.