The molecular characteristics of polycystic ovary syndrome (PCOS) ovary defined by human ovary cDNA microarray

Journal of Molecular Endocrinology

Volumn 33, Issue 1, 2004, Pages 59-72

  Diao, Fei Yang ^a   Xu, Min ^a   Hu, Yanqiu ^a   Li, Jianmin ^a   Xu, Zhiyang ^a   Lin, Min ^a   Wang, Lirong ^a   Zhou, Yadong ^a   Zhou, Zuomin ^a   Liu, Jiayin ^a   Sha, Jiahao ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ADULT; APOPTOSIS; ARTICLE; CELL DIVISION; CELL METABOLISM; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; DNA LIBRARY; DNA MICROARRAY; DOWN REGULATION; DRUG TARGETING; EXPRESSED SEQUENCE TAG; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC SCREENING; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OVARY POLYCYSTIC DISEASE; PATHOGENESIS; PRIORITY JOURNAL; UNINDEXED SEQUENCE; UPREGULATION;

BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; DNA, COMPLEMENTARY; FEMALE; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYCYSTIC OVARY SYNDROME; POLYMERASE CHAIN REACTION;

EID: 4444260304     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0330059     Document Type: Article

References (40)

1. Adams MD, Kerlavage AR & Fleischmann RD 1995 Initial assessment of human gene diversity and expression patterns based-upon 83 million nucleotides of cDNA sequence. Nature 377 1-175.
2. Arkenbout EK, de Waard V & van Bragt M 2002 Protective function of transcription factor TR3 orphan receptor in atherogenesis: decreased lesion formation in carotid artery ligation model in TR3 transgenic mice. Circulation 106 1530-1535.
3. Book CB & Dunaif A 1999 Selective insulin resistance in the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 84 3110-3116.
4. Byrjalsen I, Mose Larsen P, Fey SJ, Nilas L, Larsen MR & Christiansen C 1999 Two-dimensional gel analysis of human endometrial proteins: characterization of proteins with increased expression in hyperplasia and adenocarcinoma. Molecular Human Reproduction 5 748-756.
5. Chen YR, Kori R & John B 2001 Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis. Biochemical and Biophysical Research Communication 288 981-989.
6. De Smaele E, Zazzeroni F, Papa S, Nguyen DU, Jin R, Jones J, Cong R & Franzoso G 2001 Induction of gadd45 beta by NF-kappaB downregulates pro-apoptotic JNK signalling. Nature 414 308-313.
7. Dufresne SD, Bjorbaek C & El-Haschimi K 2001 Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice. Molecular and Cellular Biology 21 81-87.
8. Falus A, Feher KG & Walcz E 1990 Hormonal regulation of complement biosynthesis in human cell lines. I. Androgens and gamma-interferon stimulate the biosynthesis and gene expression of C1 inhibitor in human cell lines U937 and HepG2. Molecular Immunology 27 191-195.
9. Franks S, Mason H & White D 1998 Etiology of anovulation in polycystic ovary syndrome. Steroids 63 306-307.
10. Govind A, Obrhai M & Clayton R 1999 Polycystic ovaries are inherited as an autosomal dominant trait: analysis of 29 polycystic ovary syndrome and 10 control families. Journal of Clinical Endocrinology and Metabolism 84 38-43.
11. Han ED, MacFarlane RC & Mulligan AN 2002 Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor. Journal of Clinical Investigation 109 1057-1063.
12. Hastings ML & Krainer AR 2001 Pre-mRNA splicing in the new millennium. Current Opinion in Cell Biology 13 302-309.
13. Jonard S & Dewailly D 2002 Polycystic ovary syndrome: recent genetic contributions. Gynecologie, Obstetrique & Fertilite 30 603-609.
14. Kaaijk EM, Sasano H, Suzuki T, Beek JF & van der Veen F 2000 Distribution of steroidogenic enzymes involved in androgen synthesis in polycystic ovaries: an immunohistochemical study. Molecular Human Reproduction 6 443-447.
15. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR & Azziz R 1998 Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. Journal of Clinical Endocrinology and Metabolism 83 3078-3082.
16. Legro RS, Spielman R, Urbanek M, Driscoll D, Strauss JF 3rd, Dunaif A 1998 Phenotype and genotype in polycystic ovary syndrome. Hormone Research 53 217-256.
17. Legro RS, Kunselman A, Dodson WC & Dunaif A 1999 Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. Journal of Clinical Endocrinology and Metabolism 84 165-169.
18. Li H, Kolluri SK & Gu J 2000 Cytochrome c release and apoptosis induced by mitochondrial targeting of orphan receptor TR3 nuclear. Science 289 1159-1164.
19. Lin A 2003 Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25 17-24.
20. Muller G, Jung C & Wied S 1998 Structure-activity relationship of synthetic phosphoinositolglycans mimicking metabolic insulin action. Biochemistry 37 13421-13436.
21. Nelson VL, Legro RS, Strauss JF 3rd & McAllister JM 1999 Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries. Molecular Endocrinology 13 946-957.
22. Pandey AV & Synthia H 2003 Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. Journal of Biological Chemistry 278 2837-2844.
23. Park JI, Park HJ & Choi HS 2001 Gonadotropin regulation of NGFI-B messenger ribonucleic acid expression during ovarian follicle development in the rat. Endocrinology 7 3051-3059.
24. Patel NA, Chalfant CE & Watson JE 2001 Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells. Journal of Biological Chemistry 276 22648-22654.
25. Pouwels MJ, Span PN & Tack CJ 2002 Muscle uridine diphosphate-hexosamines do not decrease despite correction of hyperglycemia-induced insulin resistance in type 2 diabetes. Journal of Clinical Endocrinology and Metabolism 87 5179-5184.
26. Qi Z, Atsuchi N, Ooshima A, Takeshita A & Ueno H 1999 Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat. PNAS 96 2345-2349
27. Roach LE, Petrik JJ, Plante L, LaMarre J & Gentry PA 2002 Thrombin generation and presence of thrombin receptor in ovarian follicles. Biology of Reproduction 66 1350-1358.
28. Rosa G, Di Rocco P, Manco M, Greco AV, Castagneto M, Vidal H & Mingrone G 2003 Reduced PDK4 expression associates with increased insulin sensitivity in postobese patients. Obesity Research 11 176-182.
29. Sha JH, Zhou ZM & Li JM 2002 Identification of testis development and spermatogenesis-related genes in human and mouse testes using cDNA arrays. Molecular Human Reproduction 8 511-517.
30. Smith PJ, Spurrell EL & Coakley J 2002 An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor. Endocrinology 143 146-154.
31. Stros M, Ozaki T & Bacikova A 2002 HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter. Journal of Biological Chemistry 277 7157-7164.
32. Sugden MC 2003 PDK4: a factor in fatness? Obesity Recearch 11 167-169.
33. Tournier C, Hess P & Yang DD 2000 Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 288 870-874.
34. Wang X, Li W, Williams M & Terada N 2001 Regulation of elongation factor 2 kinase by p90 (RSK1) and p70 S6 kinase. EMBO J 20 4370-4379.
35. Watanabe K, Ozaki T & Nakagawa T 2002 Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function. Journal of Biological Chemistry 277 15113-15123.
36. Watson H, Kiddy DS, Hamilton-Fairley D, Scanlon MJ, Barnard C, Collins WP, Bonney RC & Franks S 1993 Hypersecretion of luteinizing hormone and ovarian steroids in women with recurrent early miscarriage. Human Reproduction 8 829-833.
37. Wood JR, Nelson VL & Ho C 2003 The molecular phenotype of polycystic ovary syndrome (PCOS) theca cells and new candidate PCOS genes defined by microarray analysis. Journal of Biological Chemistry 278 26380-26390.
38. Yildiz BO, Haznedaroglu IC, Kirazli S 2002 Global fibrinolytic capacity is decreased in polycystic ovary syndrome, suggesting a prothrombotic state. Journal of Clinical Endocrinology and Metabolism 87 3871-3875.
39. Zhang H, Ozaki I, Mizuta T 2002 Beta 1-integrin protects hepatoma cells from chemotherapy-induced apoptosis via a mitogen-activated protein kinase dependent pathway. Cancer 95 896-906.
40. Zhou ZM, Sha JH, Li JM 2002 Expression of a novel reticulon-like gene in human testis. Reproduction 123 227-234.