Protective function of transcription factor TR3 orphan receptor in atherogenesis: Decreased lesion formation in carotid artery ligation model in TR3 transgenic mice

Circulation

Volumn 106, Issue 12, 2002, Pages 1530-1535

  Arkenbout, E Karin ^a   De Waard, Vivian ^a   Van Bragt, Maaike ^a   Van Achterberg, Tanja A E ^a   Grimbergen, Jos M ^a   Pichon, Bruno ^a   Pannekoek, Hans ^a   De Vries, Carlie J M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Atherosclerosis; Genes; Muscle, smooth

Indexed keywords

MESSENGER RNA; MITOGEN INDUCED NUCLEAR ORPHAN RECEPTOR; RECEPTOR; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TR3; UNCLASSIFIED DRUG;

ADENOVIRUS; ADULT; AGED; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CAROTID ARTERY LIGATION; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; DNA SYNTHESIS; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTIMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SMOOTH MUSCLE FIBER; TRANSGENIC MOUSE; VIRUS INFECTION;

ADENOVIRIDAE; ANIMALS; ARTERIOSCLEROSIS; CARDIOTONIC AGENTS; CAROTID ARTERIES; DNA; DNA-BINDING PROTEINS; GENETIC VECTORS; HUMANS; MICE; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MUTATION; NERVE TISSUE PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RECEPTORS, THYROID HORMONE; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 0037126018     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000028811.03056.BF     Document Type: Article

References (21)

1. Atherosclerosis: An inflammatory disease
2. The NGFI-B subfamily of the nuclear receptor superfamily
3. Differential display identification of 40 genes with altered expression in activated human smooth muscle cells
4. Nuclear receptors nomenclature committee. A unified nomenclature system for the nuclear receptor superfamily
5. Orphan nuclear receptors: An emerging family of metabolic regulators
6. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas
7. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require immediate-early gene Nur77
8. Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
9. A role for the orphan nuclear receptor Nur77 in apoptosis accompanying antigen-induced negative selection
10. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis: A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
11. A canonical nerve growth factor-induced gene-B response element appears not to be involved in the cyclic adenosine monophosphate-dependent expression of differentiation in thyrocytes
12. Strong induction of members of the chitinase family of proteins in atherosclerosis: Chititriosidase and human cartilage gp-39 expressed in lesion macrophages
13. Expression of the SM22α promoter in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells
14. Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow
15. Structure and expression of a smooth muscle cell-specific gene, SM22α
16. Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury
17. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
18. Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation
19. A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and Nurrl
20. Modulation of retinoid signaling through NGF-induced nuclear export of NGFI-B