Sequence dependent exposure of mammary carcinoma cells to Taxotere® and the MEK1/2 inhibitor U0126 causes enhanced cell killing in vitro

Cancer Biology and Therapy

Volumn 2, Issue 6, 2003, Pages 670-676

  Yacoub, Adly ^a   Han, Song Iy ^a   Caron, Ruben ^a   Gilfor, Donna ^a   Mooberry, Susan ^c   Grant, Steven ^b   Dent, Paul ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Clonogenic; Laulimalide; MEK1 2 inhibitor; MTT; Survival; Taxane; Taxotere

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ANTINEOPLASTIC AGENT; DOCETAXEL; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; NITRILE; TAXOID;

APOPTOSIS; ARTICLE; BREAST TUMOR; CARCINOMA; DRUG ADMINISTRATION; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; FEMALE; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; BUTADIENES; CARCINOMA; CELL LINE, TUMOR; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; FEMALE; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; TAXOIDS;

EID: 4444251799     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.2.6.534     Document Type: Article

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