IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: Characterization of a new subtype of IFN-stimulated response element

Journal of Immunology

Volumn 168, Issue 12, 2002, Pages 6224-6231

  Meraro, David ^a   Gleit Kielmanowicz, Merav ^a   Hauser, Hansjörg ^a   Levi, Ben Zion ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 1; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; COMPLEX FORMATION; GENE ACTIVATION; GENE INDUCTION; IMMUNE RESPONSE; IMMUNOMODULATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; TRANSCRIPTION REGULATION;

EID: 0037097778     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.12.6224     Document Type: Article

References (40)

1. An overview of the interferon system: Signal transduction and mechanisms of action
2. Interferon regulatory factors: The next generation
3. Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family
4. Functional domain analysis of interferon consensus sequence binding protein (ICSBP) and its association with interferon regulatory factors
5. PIP. A novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator
6. Transcription factor Pip can enhance DNA binding by E47, leading to transcriptional synergy involving multiple protein domains
7. Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors
8. A two-step mechanism for recruitment of Pip by PU.1
9. A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes
10. An interferon γ-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes
11. The human interferon consensus sequence binding protein (HICSBP) is a negative regulator of enhancer elements common to interferon inducible genes
12. Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
13. ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages
14. The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages
15. PU.1/interferon regulatory factor interactions: Mechanisms of transcriptional regulation
16. Interferon-induced transcription of a gene encoding a 15 kDa protein depends on an upstream enhancer element
17. Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays
18. Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells
19. Immunoregulatory properties of ISG15, an interferon-induced cytokine
20. Precursor processing of pro-ISG15/UCRP, an interferon-β-induced ubiquitin-like protein
21. Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip 15): A possible link between interferon regulatory factor signaling and the COP9/signalosome
22. Normal myeloid development requires both the glutamine-rich transactivation domain and the PEST region of transcription factor PU.I but not the potent acidic transactivation domain
23. High efficiency transformation of mammalian cells by plasmid DNA
24. Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA
25. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
26. Functional domains of interferon regulatory factor I (IRF-1)
27. IFN consensus sequence binding protein (ICSBP) is a conditional repressor of IFN inducible promoters
28. Interferon consensus sequence binding protein and interferon regulatory factor-4/Pip form a complex that represses the expression of the interferon-stimulated gene-15 in macrophages
29. A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex
30. α-interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences
31. Interferon-induced nuclear factor that bind a shared promoter element correlate with positive and negative transcriptional control
32. Gene induction pathways mediated by distinct IRFs during viral infection
33. Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes
34. phox expression
35. Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation
36. + T cell function by the IFN-induced and double-stranded RNA-activated kinase PKR
37. The murine chemokine CXCL11 (IFN-inducible T cell α chemoattractant) is an IFN-γ- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia
38. CD81 (TAPA-1): A molecule involved in signal transduction and cell adhesion in the immune system
39. phox expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous cis elements in the CYBB and NCF2 genes
40. Transcription factor-specific requirements for coactivators and their acetyltransferase functions