Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive rat

American Journal of Hypertension

Volumn 21, Issue 6, 2008, Pages 708-714

  Brosnan, M Julia ^a,b   Carkner, Richard D ^a  

^a ORDWAY RESEARCH INSTITUTE   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; FRUCTOSE; LINOLEIC ACID; OLEIC ACID; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; HYPERTENSION; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROKE; TELEMETRY; WESTERN BLOTTING;

ANIMALS; BLOOD PRESSURE; DIETARY CARBOHYDRATES; FRUCTOSE; GLUCOSE INTOLERANCE; HYPERTENSION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LINOLEIC ACID; LIVER; MALE; METABOLIC SYNDROME X; MITOGEN-ACTIVATED PROTEIN KINASE 8; NF-KAPPA B; OLEIC ACID; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPEROXIDE DISMUTASE; TRIGLYCERIDES;

EID: 44349183900     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2008.41     Document Type: Article

References (37)

1. Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet 1999; 21:76-83.
2. Strahorn P, Graham D, Charchar FJ, Sattar N, McBride MW, Dominiczak AF. Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat. J Hypertens 2005; 23:2179-2186.
3. Bezerra RM, Ueno M, Silva MS, Tavares DQ, Carvalho CR, Saad MJ, Gontijo JA. A high-fructose diet induces insulin resistance but not blood pressure changes in normotensive rats. Braz J Med Biol Res 2001; 34:1155-1160.
4. D'Angelo G, Elmarakby AA, Pollock DM, Stepp DW. Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension 2005; 46:806-811.
5. Hsieh PS. Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats. J Hypertens 2005; 23:2209-2217.
6. Vasudevan H, Nagareddy PR, McNeill JH. Gonadectomy prevents endothelial dysfunction in fructose-fed male rats, a factor contributing to the development of hypertension. Am J Physiol Heart Circ Physiol 2006; 291:H3058-H3064.
7. Girard A, Madani S, Boukortt F, Cherkaoui-Malki M, Belleville J, Prost J. Fructose-enriched diet modifies antioxidant status and lipid metabolism in spontaneously hypertensive rats. Nutrition 2006; 22:758-766.
8. James DJ, Cairns F, Salt IP, Murphy GJ, Dominiczak AF, Connell JM, Gould GW. Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin. Diabetes 2001; 50:2148-2156.
9. Melancon S, Bachelard H, Badeau M, Bourgoin F, Pitre M, Lariviere R, Nadeau A. Effects of high-sucrose feeding on insulin resistance and hemodynamic responses to insulin in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2006; 290:H2571-H2581.
10. Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, Scherer PE. The hyperglycemia-induced inflammatory response in adipocytes: The role of reactive oxygen species. J Biol Chem 2004; 280:4617-4626.
11. Houstis N, Rosen ED, Lander ES. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 2006; 440:944-948.
12. Flowers MT, Miyazaki M, Liu X, Ntambi JM. Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance. J Clin Invest 2006; 116:1478-1481.
13. Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci USA 2002; 99:11482-11486.
14. Brosnan MJ, Hamilton CA, Graham D, Lygate CA, Jardine E, Dominiczak AF. Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats. J Hypertens 2002; 20:281-286.
15. Miller WH, Brosnan MJ, Graham D, Nicol CG, Morecroft I, Channon KM, Danilov SM, Reynolds PN, Baker AH, Dominiczak AF. Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats. Mol Ther 2005; 12:321-327.
16. Hamilton CA, Brosnan MJ, Al-Benna S, Berg G, Dominiczak AF. NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension 2002; 40:755-762.
17. Peinnequin A, Mouret C, Birot O, Alonso A, Mathieu J, Clarencon D, Agay D, Chancerelle Y, Multon E. Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green. BMC Immunol 2004; 5:3.
18. Weng Y, DiRusso CC, Reilly AA, Black PN, Ding X. Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype. J Biol Chem 2005; 280:31686-31698.
19. Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. IκK-β links inflammation to obesity-induced insulin resistance. Nat Med 2005; 11:191-198.
20. Basciano H, Federico L, Adeli K. Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab (Lond) 2005; 2:5.
21. Gross LS, Li L, Ford ES, Liu S. Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr 2004; 79:774-779.
22. Delbosc S, Paizanis E, Magous R, Araiz C, Dimo T, Cristol JP, Cros G, Azay J. Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis 2005; 179:43-49.
23. Zimmet P, Magliano D, Matsuzawa Y, Alberti G, Shaw J. The metabolic syndrome: a global public health problem and a new definition. J Atheroscler Thromb 2005; 12:295-300.
24. Miyazaki M, Dobrzyn A, Man WC, Chu K, Sampath H, Kim HJ, Ntambi JM. Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J Biol Chem 2004; 279:25164-25171.
25. Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM. Stearoyl CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem 2007; 282:2483-2493.
26. Gudbrandsen OA, Hultstrom M, Leh S, Monica Bivol L, Vagnes O, Berge RK, Iversen BM. Prevention of hypertension and organ damage in 2-kidney, 1-clip rats by tetradecylthioacetic acid. Hypertension 2006; 48:460-466.
27. Wei Y, Wang D, Pagliassotti MJ. Fructose selectively modulates c-jun N-terminal kinase activity and insulin signaling in rat primary hepatocytes. J Nutr 2005; 135:1642-1646.
28. Kelley GL, Allan G, Azhar S. High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation. Endocrinology 2004; 145:548-555.
29. Wei Y, Pagliassotti MJ. Hepatospecific effects of fructose on c-jun NH2-terminal kinase: implications for hepatic insulin resistance. Am J Physiol Endocrinol Metab 2004; 287:E926-E933.
30. Busserolles J, Rock E, Gueux E, Mazur A, Grolier P, Rayssiguier Y. Short-term consumption of a high-sucrose diet has a pro-oxidant effect in rats. Br J Nutr 2002; 87:337-342.
31. Busserolles J, Zimowska W, Rock E, Rayssiguier Y, Mazur A. Rats fed a high sucrose diet have altered heart antioxidant enzyme activity and gene expression. Life Sci 2002; 71:1303-1312.
32. Faraci FM and Didion SP. Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscler Thromb Vasc Biol 2004; 24:1367-1373.
33. Macmillan-Crow LA, Cruthirds DL. Invited review: manganese superoxide dismutase in disease. Free Radic Res 2001; 34:325-336.
34. Fennell JP, Brosnan MJ, Frater AJ, Hamilton CA, Alexander MY, Nicklin SA, Heistad DD, Baker AH, Dominiczak AF. Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension. Gene Ther 2002; 9:110-117.
35. Fortepiani LA, Reckelhoff JF. Increasing oxidative stress with molsidomine increases blood pressure in genetically hypertensive rats but not normotensive controls. Am J Physiol Regul Integr Comp Physiol 2005; 289:R763-R770.
36. Schepetkin IA. Lucigenin as a substrate of microsomal NAD(P)H-oxidoreductases. Biochemistry (Mosc) 1999; 64:25-32.
37. Zou AP, Li N, Cowley AW Jr. Production and actions of superoxide in the renal medulla. Hypertension 2001; 37:547-553.