SloR modulation of the Streptococcus mutans acid tolerance response involves the GcrR response regulator as an essential intermediary

Microbiology

Volumn 154, Issue 4, 2008, Pages 1132-1143

  Dunning, Daniel W ^a   McCall, Lathan W ^a   Powel Jr , William F ^a   Arscott, W Tristram ^a   McConocha, Erin M ^a   McClurg, Cheryl J ^a   Goodman, Steven D ^b   Spatafora, Grace A ^a  

^a MIDDLEBURY COLLEGE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE; MUTANT PROTEIN; PROTEIN GCRR; PROTEIN SLOR; REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

ACID TOLERANCE; ACIDITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; CELL GROWTH; CONTROLLED STUDY; CULTURE MEDIUM; DOWNSTREAM PROCESSING; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE INSERTION; GENE MUTATION; GENETIC CODE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOCOCCUS MUTANS; TRANSCRIPTION REGULATION; WILD TYPE;

ACIDS; BACTERIAL PROTEINS; DNA, BACTERIAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION PROFILING; GENE ORDER; HUMANS; INDEL MUTATION; MANGANESE; MICROBIAL VIABILITY; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STREPTOCOCCUS MUTANS; TRANSCRIPTION FACTORS;

STREPTOCOCCUS MUTANS;

EID: 44349175543     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.2007/012492-0     Document Type: Article

References (50)

1. 0-ATPase is regulated by pH at the step of assembly. Eur J Biochem 259, 262-268.
2. Cotter, P. D. & Hill, C. (2003). Surviving the acid test: responses of Gram-positive bacteria to low pH. Microbiol Mol Biol Rev 67, 429-453.
3. Cotter, P. D., Emerson, N., Gatian, C. G. & Hill, C. (1999). Identification and disruption of lisRK, a genetic locus encoding a two-component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes. J Baaeriol 181, 6840-6843.
4. Crowley, P. J., Svensater, G., Snoep, J. L., Bleiweis, A. S. & Brady, L. J. (2004). An ffh mutant of Streptococcus mutans is viable and able to physiologically adapt to low pH in continuous culture. FEMS Microbiol Lett 234, 315-324.
5. Dalton, T. L. & Scott, J. R. (2004). CovS inactivates CoR and is required for growth undex conditions of general stress in Streptococcus pyogenes. J Bacteriol 186, 3928-3937.
6. Farber, J. M. & Peterkin, P. I. (1991). Listeria monocytogenes, a food-borne pathogen. Microbiol Rev 55, 476-511.
7. B in heat, ethanol, acid, and oxidative stress resistance and during carbon starvation in Listeria monocytogenes. Appl Environ Microbiol 67, 4454-4457.
8. Flahaut, S., Frere, J., Boutibonnes, P. & Auffray, Y. (1996a). Comparison of the bile salts and sodium dodecyl sulfate stress responses in Enterococcus faecalis. Appl Ensiron Microbiol 62, 2416-2420.
9. Flahaut S., Hartke, A., Giard, J. C., Benachour, A., Boutibonnes, P. & Auffray, Y. (1996b). Relationship between stress response toward bile salts, acid and heat treatment in Enterococcus faecalis. FEMS Microbiol Lett 138, 49-54.
10. Foster, J. W. & Hall, H. K. (1990). Adaptive acidification tolerance response of Salmonella typhimurium. J Bacteriol 172, 771-778.
11. Fozo, E. M. & Quivey, R. G., Jr (2004). The fabM gene product of Streptococcus mutans is responsible for the synthesis of monounsaturated fatty acids and is necessary for survival at low pH. J Bacteriol 186, 4152-4158.
12. Fozo, E. M., Scott-Anne, K., Koo, H. & Quivey, R. G., Jr (2007). Role of unsaturated fatty acid biosynthesis in virulence of Streptococcus mutans. Infect Immun 75, 1537-1539.
13. Graham, M. R., Smmot, L M., Lux Migliaccio, C. A., Virtaneva, K., Sturdevant D. E., Porcella, S. F., Federle, M. J., Adams, G. J., Scott, J. R. & Musser, J. M. (2002). Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci U S A 99, 13855-13860.
14. Griswold, A. R., Jameson-Lee, M. & Burne, R. A. (2006). Regulation and physiologic significance of the agmatine deiminase system of Streptococcus mutans UA159. J Bacteriol 188, 834-841.
15. Gutierrez, J. A., Crowley, P. J., Cvitkovitch, D. G., Brady, L. J., Hamilton, I. R., Hillman, J. D. & Bleiweis, A. S. (1999). Streptococcus mutans ffh, a gene encoding a homologue of the 54 kDa subunit of the signal recognition particle, is involved in resistance to acid stress. Microbiology 145, 357-366.
16. Hamilton, I. R. & Buckley, N. D. (1991). Adaptation by Streptococcus mutans to acid tolerance. Oral Microbiol Immunol 6, 65-71.
17. Hamilton, I. R. & Svensater, G. (1998). Acid-regulated proteins induced by Streptococcus mutans and other oral bacteria during acid shock. Oral Microbiol Immunol 13, 292-300.
18. Hanna, M. N., Ferguson, R. J. & Cvitkovitch, D. G. (2001). uvrA is an acid-inducible gene involved in the adaptive response to low PH in Streptococcus mutans. J Bacteriol 183, 5964-5973.
19. Idone, V., Brendtro, S, Gillespie, R., Kocal, S., Peterson, E., Rendi, M., Warren, W., Mickalek, S., Krastel, K. & other authors (2003). Effect of an orphan response regulator on S. mutans sucrose-dependent adherence and cariogenesis. Infect Immun 71, 4351-4360.
20. Jayaraman, G. C., Panders, J. E. & Burne, R. A. (1997). Transcriptional analysis of the Streptococcus mutans hrcA, gypE and dnaK genes and regulation of expression in response to heat shock and environmental acidification. Mol Microbiol 25, 329-341.
21. Jensen, M. E., Polansky, P. J. & Schachtele, C. F. (1982). Plaque sampling and telemetry for monitoring acid production on human buccal tooth surfaces. Arch Oral Biol 27, 21-31.
22. Jiang, S.-M., Cieslewica, M. J., Kasper, D. L. & Wessels, M. R. (2005). Regulation of virulence by a two-component system in group B Streptococcus. J Bacteriol 187, 1105-1113.
23. Kitten, T., Munro, C. L., Michalek, S. M. & Macrina, F. L (2000). Genetic characterization of a Streptococcus mutans Lral family operon, and role in virulence. Infect Immun 68, 4441-4451.
24. Korithoski, B., Krastel, K. & Cvitkovitch, D. G. (2005). Transport and metabolism of citrate by Streptococcus mutans. J Bacteriol 187, 4451-4456.
25. Kuhnert, W. L., Zheng, G., Faustoferri, R. C. & Quivey, R. G., Jr (2004). The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external PH. J Bacteriol 186, 8524-8528.
26. Lamy, M. C., Zouine, M., Fart J., Vergassola, M., Couve, F., Pellegrini, E., Glaser, P., Kunst F., Msadek, T. & other authors (2004). CovS/CovR of group B streptococcus: a two-component global regulatory system involved in virulence. Mol Microbiol 54, 1250-1268.
27. Lau, P. C., Sung, C. K., Lee, J. H., Morrison, D. A. & Cvitkovitch, D. G. (2002). PCR ligation mutagenesis in transformable streptococci: application and efficiency. J Microbiol Methods 49, 193-205.
28. Leblanc, D. J. & Lee, L. N. (1979). Rapid screening procedure for detection of plasmids in streptococci. J. Bacteriol 140, 1112-1115.
29. Lemos, J. A., Chen, Y. Y. & Burne, R. A. (2001). Genetic and physiologic analysis of the groE operon and role of the HrcA repressor in stress gene regulation and acid tolerance in Streptococcus mutans. J Bacteriol 183, 6074-6084.
30. Len, A. C. L., Harty, D. W. S. & Jacques, N. A. (2004a). Stress responsive proteins are upregulated in Streptococcus mutans during acid tolerance. Microbiology 150, 1339-1351.
31. Len, A. C. L., Harty, D. W. S. & Jacques, N. A. (2004b). Proteome analysis of Streptococcus mutans metabolic phenotype during acid tolerance. Microbiology 150, 1353-1366.
32. Li, Y. H., Hanna, M. N., Svensater, G., Ellen, R. P. & Cvitkovitch, D. G. (2001a). Cell density modulates acid adaptation in Streptococcus mutans: implications for survival inbiofilms. J Bacteriol 183, 6875-6884.
33. Li, Y. H, Lau, P. C., Lee, J. H., Ellen, R. P. & Cvltkovitch, D. G. (2001b). Natural genetic transformation of Streptococcus mutans growing in biofilms. J Bacteriol 183, 897-908.
34. Li, Y. H., Lau, P. C., Tang, N., Svensater, G., Ellen, R. P. & Cvitkovitch, D. G. (2002). Novel two-component regulatory system involved in biofilm formation and acid resistance in Streptococcus mutans. J Bacteriol 184, 6333-6342.
35. Loesche, W. J. (1986). Role of Streptococcus mutans in human dental decay. Microbiol Rev 50, 353-380.
36. Macrina, F. L, Toblan, J. A., Jones, K. R., Evans, R. P. & Clewell, D. B. (1982). A cloning vector able to replicate in Escherichia coli and Streptococcus sanguis. Gene 19, 345-353.
37. Mead, P. S., Slutsker, L., Dietz, V., McCaig, L. F., Bresee, J. S., Shapiro, C., Griffin, P. M. & Tauxe, R. V. (1999). Food-related illness and death in the United States. Emerg Infect Dis 5, 607-625.
38. Nascimento, M. M., Lemos, J. A., Abranches, J., Goncalves, R. B. & Burne, R. A. (2004). Adaptive acid tolerance response of Streptococcus sobrinus. J Bacteriol 186, 6383-6390.
39. Paik S., Brown, A., Munro, C. L., Cornelissen, C. N. & Kitten, T. (2003). The sloABCR operon of Streptococcus mutans encodes an Mn and Fe transport system required for endocarditis virulence and its Mn-dependent repressor. J Bacteriol 185, 5967-5975.
40. Rolerson, E., Swick, A., Newlon, L., Palmer, C., Pan, Y., Keeshan, B. & Spatafora, G. (2006). The SloR/Dlg metalloregulator modulates Streptococcus mutans virulence gene expression. J Bacteriol 188, 5033-5044.
41. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
42. Sato, Y., Yamamoto, Y. & Kizaki, H. (2000). Construction of region-specific partial duplication mutants (merodiploid mutants) to identify the regulatory gene for the glucan-binding protein C gene in vivo in Streptococcus mutans. FEMS Microbiol Lett 186, 187-191.
43. Senadheera, M. D., Guggenheim, B., Spatafora, G. A., Yi-Chen, C. H., Choi, J., Hung, D. C. I., Treglown, J. S., Goodman, S. D., Ellen, R. P. & Cvitkovitch, D. G. (2005). A VickRK signal transduction system in streptococcus mutans affects gtjBCD, gbpA and ftf expression, biofilm formation, and genetic competence development. J Bacteriol 187, 4064-4076.
44. Smith, R. S. (2001). Naturally Occurring Hazards. Article prepared for World Water Day, Mardi 22 2001. Geneva: World Health Organization. http://www.worldwaterday.org/2001/thematic/natural.html
45. Szurmant, H., Nelson, K., Kim, E-J., Perego, M. & Hoch, J. A. (2005). YycH regulates the activity of the essential YycFG two component system in Bacillus subtilis. J Bacteriol 187, 5419-5426.
46. Tao, X., Boyd, J. & Murphy, J. R. (1992). Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence. Proc Natl Acad Sci U S A 89, 5897-5901.
47. Tang, F., Wang, L., Singh, K. V., Murray, B. E. & Weinstock, G. M. (2002). Involvement of PhoP-PhoS homologs in Enterococcus faecalis virulence. Infect Immun 70, 1991-1996.
48. US Department of Health and Human Services (2003 b). National Call to Action to Promote Oral Health. NIH publication number 03-5303. Rockville, MD: US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Dental and Craniofacial Research.
49. Wagner, C., de Saizieu, A., Schonfeld, H.-J., Kamber, M., Lange, R., Thompson, C. J. & Page, M. G. (2002). Genetic analysis and functional characterization of the Streptococcus pneumoniae vic operon. Infect Immun 70, 6121-6128.
50. Workman, C., Jensen, L. J., Jarmer, H., Barka, R., Gautier, L., Nielser, H. B., Saxild, H. H., Nielsen, C., Brunak, S. & Knudsen, S. (2002). A new non-linear normalization method for reducing variability in DNA microarray experiments. Genome Biol 3, research0048004816