Identification and disruption of lisRK, a genetic locus encoding a two- component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes

Journal of Bacteriology

Volumn 181, Issue 21, 1999, Pages 6840-6843

  Cotter, Paul D ^a   Emerson, Nathan ^a   Gahan, Cormac G M ^a   Hill, Colin ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ACID; ALCOHOL; AMINO ACID; DNA; PHOSPHOTRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL VIRULENCE; CARBOXY TERMINAL SEQUENCE; DNA SEQUENCE; GENE; GENE DISRUPTION; LISTERIA MONOCYTOGENES; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING; STRESS;

LISTERIA MONOCYTOGENES;

EID: 0032721978     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.21.6840-6843.1999     Document Type: Article

References (27)

1. Bielecki, J., P. Youngman, P. Connelly, and D. A. Portnoy. 1990. Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells. Nature 345:175-176.
2. Brown, J. L., T. Ross, T. A. McMeekin, and P. D. Nichols. 1997. Acid habituation of Escherichia coli and the potential role of cyclopropane fatty acids in low pH tolerance. Int. J. Food Microbiol. 37:163-173.
3. Camilli, A., H. Goldfine, and D. A. Portnoy. 1991. Listeria monocytogenes mutants lacking phosphatidyl-specific phospholipase C are avirulent. J. Exp. Med. 173:751-754.
4. Chou, L. S., and B. Weimer. 1999. Isolation and characterization of acid- and bile-tolerant isolates from strains of Lactobacillus acidophilus. J. Dairy Sci. 82:23-31.
5. Correa, O. S., E. A. Rivas, and A. J. Barneix. 1999. Cellular envelopes and tolerance to acid pH in Mesorhizobium loti. Curr. Microbiol. 38:329-334.
6. Datta, A. R., and M. H. Kothary. 1993. Effects of glucose, growth temperature, and pH on listeriolysin O production in Listeria monocytogenes. Appl. Environ. Microbiol. 59:3495-3497.
7. Dons, L., J. E. Olsen, and O. F. Rasmussen. 1994. Characterization of two putative Listeria monocytogenes genes encoding polypeptides homologous to the sensor protein CheA and the response regulator CheY of chemotaxis. DNA Sequence 4:301-311.
8. Forst, S. A., and D. L. Roberts. 1994. Signal transduction by the EnvZ-OmpR phosphotransfer system in bacteria. Res. Microbiol. 145:363-373.
9. Gahan, C. G. M., and J. K. Collins. 1995. Non-dystrophic 129 REJ mice are susceptible to i.p. infection with Listeria monocytogenes despite an ability to recruit inflammatory neutrophils to the peritoneal cavity. Microb. Pathog. 18:355-364.
10. Gaillard, J.-L., P. Berche, J. Mounier, S. Richard, and P. Sansonetti. 1987. In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2. Infect. Immun. 55:2822-2829.
11. Garcia Vescovi, E., F. C. Soncini, and E. A. Groisman. 1994. The role of the PhoP/PhoQ regulon in Salmonella virulence. Res. Microbiol. 145:473-480.
12. Gutierrez, J. A., P. J. Crowley, D. P. Brown, J. D. Hillman, P. Youngman, and A. S. Bleiweis. 1996. Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: preliminary characterization of mutants displaying acid sensitivity and nutritional requirements. J. Bacteriol. 178:4166-4175.
13. Horton, R. M., Z. Cai, S. N. Ho, and L. R. Pease. 1990. Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. BioTechniques 8:528-534.
14. Ingram, L. O., N. S. Vreeland, and L. C. Eaton. 1980. Alcohol tolerance in Escherichia coli. Pharmacol. Biochem. Behav. 13:191-195.
15. Ingram, L. O., and T. M. Buttke. 1984. Effects of alcohols on micro-organisms. Adv. Microb. Physiol. 25:253-300.
16. Kongshavn, P. A. L. 1985. Genetic control of the murine listeriosis expressed in the macrophage response. Immunol. Lett. 11:181-188.
17. Levin, J. L., and M. R. Wessels. 1998. Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus. Mol. Microbiol. 30:209-219.
18. Marron, L., N. Emerson, C. G. M. Gahan, and C. Hill. 1997. A mutant of Listeria monocytogenes LO28 unable to induce an acid tolerance response displays diminished virulence in a murine model. Appl. Environ. Microbiol. 63:4945-4947.
19. O'Connell-Motherway, M., G. F. Fitzgerald, and D. van Sinderen. 1997. Cloning and sequence analysis of putative histidine protein kinases isolated from Lactococcus lactis MG1363. Appl. Environ. Microbiol. 63:2454-2459.
20. O'Driscoll, B., C. G. M. Gahan, and C. Hill. 1996. Adaptive acid tolerance response in Listeria monocytogenes: isolation of an acid-tolerant mutant which demonstrates increased virulence. Appl. Environ. Microbiol. 62:1693-1698.
21. Parkinson, J. S. 1993. Signal transduction schemes of bacteria. Cell 73:857-871.
22. Rouquette, C., M. T. Ripio, E. Pellegrini, J. M. Bolla, R. L. Tascon, J. A. Vasquez-Boland, and P. Berche. 1996. Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes. Mol. Microbiol. 21:977-987.
23. Sikkema, J., J. A. M. de Bont, and B. Poolman. 1995. Mechanisms of membrane toxicity of hydrocarbons. Microbiol. Rev. 59:201-222.
24. Small, P. L. C., L. Ramakrishanan, and S. Falkow. 1994. Remodeling schemes of intracellular pathogens. Science 263:637-639.
25. Smith, K., and P. Youngman. 1992. Use of a new integrational vector to investigate compartment-specific expression of the Bacillus subtilis spoIIM gene. Biochimie 74:705-711.
26. Sokolovic, Z., J. Riedel, M. Wuenscher, and W. Goebel. 1993. Surface-associated, PrfA-regulated proteins of Listeria monocytogenes synthesized under stress conditions. Mol. Microbiol. 8:219-227.
27. Stock, J. B., A. J. Ninfa, and A. M. Stock. 1989. Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol. Rev. 53:450-490.