Characterization of alkanoyl-10-O-minocyclines in micellar dispersions as potential agents for treatment of human neurodegenerative disorders

European Journal of Pharmaceutical Sciences

Volumn 34, Issue 2-3, 2008, Pages 118-128

  Di Stefano, Antonio ^a   Sozio, Piera ^a   Iannitelli, Antonio ^a   Cerasa, Laura Serafina ^a   Fontana, Antonella ^a   Di Biase, Giuseppe ^a   D'Amico, Guglielmo ^a   Di Giulio, Mara ^a   Carpentiero, Carmen ^b   Grumetto, Lucia ^b   Barbato, Francesco ^b  

^a UNIVERSITY OF CHIETI   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Brain targeting; IAM; Lipophilicity; Micellar aggregates; Minocycline; Phospholipid partition

Indexed keywords

10 O MINOCYCLINE; MEMBRANE PHOSPHOLIPID; MINOCYCLINE; OCTANOL;

ALKYLATION; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; ARTIFICIAL MEMBRANE; BLOOD BRAIN BARRIER; CRITICAL MICELLE CONCENTRATION; DEGENERATIVE DISEASE; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STRUCTURE; ESCHERICHIA COLI; IMMOBILIZED ARTIFICIAL MEMBRANE; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; NEUROPROTECTION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS MUTANS;

ALKANES; ALKYLATION; ANTI-BACTERIAL AGENTS; BACTERIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INDICATORS AND REAGENTS; MICELLES; MICROBIAL SENSITIVITY TESTS; MINOCYCLINE; NEURODEGENERATIVE DISEASES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 44349171138     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.02.123     Document Type: Article

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