LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: Application to a pharmacokinetic study in healthy volunteers

Xenobiotica

Volumn 33, Issue 12, 2003, Pages 1261-1271

  Chen, X Y ^a   Zhong, D F ^a   Duan, J L ^b   Yan, B X ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRIDYLACETIC ACID; ACETIC ACID DERIVATIVE; BETAHISTINE; DRUG METABOLITE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CALCULATION; CONTROLLED STUDY; DRUG METABOLISM; ELECTROSPRAY MASS SPECTROMETRY; FIRST PASS EFFECT; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NORMAL HUMAN; PLASMA; QUALITY CONTROL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 1642539177     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/0049825039117001     Document Type: Article

References (10)

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