Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas

Hepatology Research

Volumn 37, Issue 11, 2007, Pages 974-983

  Kondo, Yutaka ^a   Shen, Lanlan ^b   Suzuki, Seiji ^c   Kurokawa, Tsuyoshi ^d   Masuko, Kazuo ^e   Tanaka, Yasuhito ^c   Kato, Hideaki ^c   Mizuno, Yoshiki ^f   Yokoe, Masamichi ^f   Sugauchi, Fuminaka ^c   Hirashima, Noboru ^c   Orito, Etsuro ^c   Osada, Hirotaka ^a   Ueda, Ryuzo ^c   Guo, Yi ^b   Chen, Xinli ^b   Issa, Jean Pierre J ^b   Sekido, Yoshitaka ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^d AICHI MEDICAL UNIVERSITY   (Japan)

^e Masuko Memorial Hospital   (Japan)

^f Higashi Municipal Hospital   (Japan)

Author keywords

DNA methylation; EZH2; G9a; Hepatocellular carcinoma; Histone methylation; Histone modification

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; ENHANCER OF ZESTE HOMOLOG 2 PROTEIN; ESTROGEN RECEPTOR ALPHA; HISTONE; HISTONE H3; HISTONE H3 K27; HISTONE H3 K4; HISTONE H3 K9; HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE EZH2; HISTONE METHYLTRANSFERASE G9A; HISTONE METHYLTRANSFERASE SUV39H1; PROGESTERONE RECEPTOR; PROTEIN P16; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FEMALE; GENE SEQUENCE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

EID: 34548645031     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2007.00141.x     Document Type: Article

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