Thymic Epithelial Neoplasms: A Review of Current Concepts Using an Evidence-Based Pathology Approach

Hematology/Oncology Clinics of North America

Volumn 22, Issue 3, 2008, Pages 543-562

  Marchevsky, Alberto M ^a   McKenna Jr , Robert J ^b   Gupta, Ruta ^a  

^a Cedars Sinai Medical Center   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL PRACTICE; CLINICAL TRIAL; DISEASE CLASSIFICATION; EPITHELIUM CELL; EVIDENCE BASED MEDICINE; HISTOPATHOLOGY; HUMAN; POSTOPERATIVE CARE; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGNOSIS; REVIEW; THYMOMA; THYMUS CANCER; WORLD HEALTH ORGANIZATION;

EVIDENCE-BASED MEDICINE; HUMANS; THYMOMA; THYMUS NEOPLASMS; WORLD HEALTH ORGANIZATION;

EID: 44249115550     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2008.03.006     Document Type: Review

References (133)

1. Banning M. Approaches to teaching: current opinions and related research. Nurse Educ Today 25 7 (2005) 502-508
2. Straus S.E., Green M.L., Bell D.S., et al. Evaluating the teaching of evidence based medicine: conceptual framework. BMJ 329 7473 (2004) 1029-1032
3. Crawford J.M. Original research in pathology: judgment, or evidence-based medicine?. Lab Invest 87 2 (2007) 104-114
4. Ghosh A.K. Understanding medical uncertainty: a primer for physicians. J Assoc Physicians India 52 (2004) 739-742
5. Eisenberg J.M., and Zarin D. Health technology assessment in the United States. Past, present, and future. Int J Technol Assess Health Care 18 2 (2002) 192-198
6. Sackett D.L., Straus S.E., Richardson W.S., et al. Evidence-based medicine. How to practice and teach EBM (2001), Churchill Livingstone, London
7. Schoenfeld P. Evidence based medicine (EBM) in practice: applying relative risk and relative risk reduction. Am J Gastroenterol 99 11 (2004) 2084-2085
8. Dunn M.J. Teaching, integrating and enhancing EBM. WMJ 104 3 (2005) 53-54
9. Straus S.E. What's the E for EBM?. BMJ 328 7439 (2004) 535-536
10. Parker M. False dichotomies: EBM, clinical freedom, and the art of medicine. Med Humanit 31 1 (2005) 23-30
11. Marchevsky A.M., and Wick M.R. Current controversies regarding the role of asbestos exposure in the causation of malignant mesothelioma: the need for an evidence-based approach to develop medicolegal guidelines. Ann Diagn Pathol 7 5 (2003) 321-332
12. Marchevsky A.M., and Wick M.R. Evidence-based guidelines for the utilization of immunostains in diagnostic pathology: pulmonary adenocarcinoma versus mesothelioma. Appl Immunohistochem Mol Morphol 15 2 (2007) 140-144
13. Marchevsky A. Evidence-based medicine in pathology: an introduction. Semin Diagn Pathol 22 (2005) 105-115
14. Marchevsky A., and Wick M. Evidence-based medicine, medical decision analysis, and pathology. Hum Pathol 35 10 (2004) 1179-1188
15. Marchevsky A.M., Harber P., Crawford L., et al. Mesothelioma in patients with nonoccupational asbestos exposure. An evidence-based approach to causation assessment. Ann Diagn Pathol 10 4 (2006) 241-250
16. Costa J. Reflections about evidence-based pathology. Int J Surg Pathol 15 3 (2007) 230-232
17. Strite S., and Stuart M.E. Evaluating clinical literature. Fam Pract Manag 11 9 (2004) 14 16
18. Woolf S.H., and George J.N. Evidence-based medicine. Interpreting studies and setting policy. Hematol Oncol Clin North Am 14 4 (2000) 761-784
19. Von K.L. Evidence-based medicine, randomized controlled trials, publication bias, patient population, follow-up and access. Nord J Psychiatry 57 4 (2003) 251
20. Griffiths P. Evidence-based practice: a deconstruction and postmodern critique: book review article. Int J Nurs Stud 42 3 (2005) 355-361
21. Altman D.G., and Burton M.J. The Cochrane Collaboration. Langenbecks Arch Surg 384 5 (1999) 432-436
22. Fitzpatrick R.B. The Cochrane Library and Cochrane Collaboration. Med Ref Serv Q 19 4 (2000) 73-78
23. Condon R.E. Cochrane review and meta-analysis. J Am Coll Surg 198 3 (2004) 498-500
24. Dickersin K., Manheimer E., Wieland S., et al. Development of the Cochrane Collaboration's central register of controlled clinical trials. Eval Health Prof 25 1 (2002) 38-64
25. Petrisor B.A., Keating J., and Schemitsch E. Grading the evidence: levels of evidence and grades of recommendation. Injury 37 4 (2006) 321-327
26. Grimshaw J. So what has the Cochrane Collaboration ever done for us? A report card on the first 10 years. CMAJ 171 7 (2004) 747-749
27. Mallett S., and Clarke M. The typical Cochrane review. How many trials? How many participants?. Int J Technol Assess Health Care 18 4 (2002) 820-823
28. Sutton A.J., Cooper N.J., Abrams K.R., et al. A Bayesian approach to evaluating net clinical benefit allowed for parameter uncertainty. J Clin Epidemiol 58 1 (2005) 26-40
29. Sutton A.J., and Abrams K.R. Bayesian methods in meta-analysis and evidence synthesis. Stat Methods Med Res 10 4 (2001) 277-303
30. Sheingold S.H. Can Bayesian methods make data and analyses more relevant to decision makers? A perspective from Medicare. Int J Technol Assess Health Care 17 1 (2001) 114-122
31. Ashby D., and Smith A.F. Evidence-based medicine as Bayesian decision-making. Stat Med 19 23 (2000) 3291-3305
32. Schoenfeld P.S., and Loftus Jr. E.V. Evidence-based medicine (EBM) in practice: understanding tests of heterogeneity in metaanalysis. Am J Gastroenterol 100 6 (2005) 1221-1223
33. Shekelle P.G., and Morton S.C. Principles of metaanalysis. J Rheumatol 27 1 (2000) 251-252
34. Rawlins M.D. 5 nice years. Lancet 365 9462 (2005) 904-908
35. Burgers J.S., and Van Everdingen J.J. Beyond the evidence in clinical guidelines. Lancet 364 9432 (2004) 392-393
36. Jackson N., and Waters E. The challenges of systematically reviewing public health interventions. J Public Health (Oxf) 26 3 (2004) 303-307
37. McGaw C.D., Ehikhametalor E., Nelson M., et al. The challenges of translating evidence-based guidelines into clinical practice. West Indian Med J 53 4 (2004) 205-207
38. Cheng Y.J., Hsu J.S., and Kao E.L. Characteristics of thymoma successfully resected by videothoracoscopic surgery. Surg Today 37 3 (2007) 192-196
39. Evoli A., Minicuci G.M., Vitaliani R., et al. Paraneoplastic diseases associated with thymoma. J Neurol 254 6 (2007) 756-762
40. Kawaguchi K., Usami N., Uchiyama M., et al. Triple thymoma with different histologic types. J Thorac Cardiovasc Surg 133 3 (2007) 826-827
41. Lucchi M., Basolo F., Ribechini A., et al. Thymomas: clinical-pathological correlations. J Cardiovasc Surg (Torino) 47 1 (2006) 89-93
42. Riedel R.F., and Burfeind Jr. W.R. Thymoma: benign appearance, malignant potential. Oncologist 11 8 (2006) 887-894
43. Suster S. Diagnosis of thymoma. J Clin Pathol 59 12 (2006) 1238-1244
44. Suster S., and Moran C.A. Thymoma classification: current status and future trends. Am J Clin Pathol 125 4 (2006) 542-554
45. Suster S., and Moran C.A. Thymoma classification. The ride of the valkyries?. Am J Clin Pathol 112 3 (1999) 308-310
46. Lewis J.E., Wick M.R., Scheithauer B.W., et al. Thymoma. A clinicopathologic review. Cancer 60 11 (1987) 2727-2743
47. Bernatz P.E., Khonsari S., Harrison Jr. E.G., et al. Thymoma: factors influencing prognosis. Surg Clin North Am 53 4 (1973) 885-892
48. Bernatz P.E., Harrison E.G., and Clagett O.T. Thymoma: a clinicopathologic study. J Thorac Cardiovasc Surg 42 (1961) 424-444
49. Levine G.D., and Rosai J. Thymic hyperplasia and neoplasia: a review of current concepts. Hum Pathol 9 5 (1978) 495-515
50. Masunaga A., Sugawara I., Yoshitake T., et al. A case of encapsulated noninvasive thymoma (stage I) with myasthenia gravis showing metastasis after a 2-year dormancy. Surg Today 25 4 (1995) 369-372
51. Marino M., and Muller-Hermelink H.K. Thymoma and thymic carcinoma. Relation of thymoma epithelial cells to the cortical and medullary differentiation of thymus. Virchows Arch A Pathol Anat Histopathol 407 2 (1985) 119-149
52. Muller-Hermelink H.K., Marino M., Palestro G., et al. Immunohistological evidences of cortical and medullary differentiation in thymoma. Virchows Arch A Pathol Anat Histopathol 408 2-3 (1985) 143-161
53. Papla B., Rudnicka L., Dubiel-Bigaj M., et al. Thymomas and thymic carcinomas. Evaluation of the Muller-Hermelink classification. Pol J Pathol 49 4 (1998) 251-265
54. Suster S., and Moran C.A. Problem areas and inconsistencies in the WHO classification of thymoma. Semin Diagn Pathol 22 3 (2005) 188-197
55. Suster S., and Moran C.A. Thymoma, atypical thymoma, and thymic carcinoma. A novel conceptual approach to the classification of thymic epithelial neoplasms. Am J Clin Pathol 111 6 (1999) 826-833
56. Suster S., and Moran C.A. Primary thymic epithelial neoplasms showing combined features of thymoma and thymic carcinoma. A clinicopathologic study of 22 cases. Am J Surg Pathol 20 12 (1996) 1469-1480
57. Detterbeck F.C. Clinical value of the WHO classification system of thymoma. Ann Thorac Surg 81 6 (2006) 2328-2334
58. Strobel P., Marx A., Zettl A., et al. Thymoma and thymic carcinoma: an update of the WHO classification 2004. Surg Today 35 10 (2005) 805-811
59. Kondo K., Yoshizawa K., Tsuyuguchi M., et al. WHO histologic classification is a prognostic indicator in thymoma. Ann Thorac Surg 77 4 (2004) 1183-1188
60. Chalabreysse L., Roy P., Cordier J.F., et al. Correlation of the WHO schema for the classification of thymic epithelial neoplasms with prognosis: a retrospective study of 90 tumors. Am J Surg Pathol 26 12 (2002) 1605-1611
61. Chen G., Marx A., Wen-Hu C., et al. New WHO histologic classification predicts prognosis of thymic epithelial tumors: a clinicopathologic study of 200 thymoma cases from China. Cancer 95 2 (2002) 420-429
62. Okumura M., Ohta M., Miyoshi S., et al. Oncological significance of WHO histological thymoma classification. A clinical study based on 286 patients. Jpn J Thorac Cardiovasc Surg 50 5 (2002) 189-194
63. Nagata Y., Ohno K., Utsumi T., et al. Large cell neuroendocrine thymic carcinoma coexisting within large WHO type AB thymoma. Jpn J Thorac Cardiovasc Surg 54 6 (2006) 256-259
64. Hasserjian R.P., Strobel P., and Marx A. Pathology of thymic tumors. Semin Thorac Cardiovasc Surg 17 1 (2005) 2-11
65. Detterbeck F.C., and Parsons A.M. Thymic tumors. Ann Thorac Surg 77 5 (2004) 1860-1869
66. Eng T.Y., Fuller C.D., Jagirdar J., et al. Thymic carcinoma: state of the art review. Int J Radiat Oncol Biol Phys 59 3 (2004) 654-664
67. Kurup A., and Loehrer Sr. P.J. Thymoma and thymic carcinoma: therapeutic approaches. Clin Lung Cancer 6 1 (2004) 28-32
68. Travis W.D., Brambilla E., Muller-Hermelink H.K., et al. Tumors of the lung, pleura, thymus and heart. World Health Organization Classification of Tumours (2004), IARC Press, Lyon (France)
69. Lardinois D., Rechsteiner R., Lang R.H., et al. Prognostic relevance of Masaoka and Muller-Hermelink classification in patients with thymic tumors. Ann Thorac Surg 69 5 (2000) 1550-1555
70. Muller-Hermelink H.K., and Marx A. Thymoma. Curr Opin Oncol 12 5 (2000) 426-433
71. Harris N.L., and Muller-Hermelink H.K. Thymoma classification. A siren's song of simplicity. Am J Clin Pathol 112 3 (1999) 299-303
72. Wright C.D., and Kessler K.A. Surgical treatment of thymic tumors. Semin Thorac Cardiovasc Surg 17 1 (2005) 20-26
73. Sonobe S., Miyamoto H., Izumi H., et al. Clinical usefulness of the WHO histological classification of thymoma. Ann Thorac Cardiovasc Surg 11 6 (2005) 367-373
74. Marchevsky A.M., Gupta R., McKenna R.J., et al. Evidence-based pathology and the pathologic evaluation of thymomas: the World Health Organization classification can be simplified into only 3 categories other than thymic carcinoma. Cancer (2008) in press
75. Masaoka A., Monden Y., Nakahara K., et al. Follow-up study of thymomas with special reference to their clinical stages. Cancer 48 11 (1981) 2485-2492
76. Marchevsky A.M., Hammond M.E., Moran C., et al. Protocol for the examination of specimens from patients with thymic epithelial tumors located in any area of the mediastinum. Arch Pathol Lab Med 127 10 (2003) 1298-1303
77. Nomori H., Horio H., Morinaga S., et al. Minimally invasive thymoma with extensive intravascular growth. Jpn J Clin Oncol 29 12 (1999) 630-632
78. Kaiser L.R. Thymoma. The use of minimally invasive resection techniques. Chest Surg Clin N Am 4 1 (1994) 185-194
79. Bedini A.V., Andreani S.M., Tavecchio L., et al. Proposal of a novel system for the staging of thymic epithelial tumors. Ann Thorac Surg 80 6 (2005) 1994-2000
80. Gupta R., Marchevsky A.M., McKenna R.J., et al. Evidence-based pathology and the pathologic evaluation of thymomas: II. There is no difference in disease free and overall survival in patients with stages I and II thymomas. Arch Pathol Lab Med (2008) in press
81. Rena O., Papalia E., Oliaro A., et al. Does adjuvant radiation therapy improve disease-free survival in completely resected Masaoka stage II thymoma?. Eur J Cardiothorac Surg 31 1 (2007) 109-113
82. Cesaretti J.A. Adjuvant radiation with modern techniques is the standard of care for stage III thymoma. Ann Thorac Surg 81 3 (2006) 1180-1181
83. Bjork-Eriksson T., Bjelkengren G., and Glimelius B. The potentials of proton beam radiation therapy in malignant lymphoma, thymoma and sarcoma. Acta Oncol 44 8 (2005) 913-917
84. Mangi A.A., Wain J.C., Donahue D.M., et al. Adjuvant radiation of stage III thymoma: is it necessary?. Ann Thorac Surg 79 6 (2005) 1834-1839
85. Zhu G., He S., Fu X., et al. Radiotherapy and prognostic factors for thymoma: a retrospective study of 175 patients. Int J Radiat Oncol Biol Phys 60 4 (2004) 1113-1119
86. Singhal S., Shrager J.B., Rosenthal D.I., et al. Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation. Ann Thorac Surg 76 5 (2003) 1635-1641
87. Uematsu M., Yoshida H., Kondo M., et al. Entire hemithorax irradiation following complete resection in patients with stage II-III invasive thymoma. Int J Radiat Oncol Biol Phys 35 2 (1996) 357-360
88. Curran Jr. W.J., Kornstein M.J., Brooks J.J., et al. Invasive thymoma: the role of mediastinal irradiation following complete or incomplete surgical resection. J Clin Oncol 6 11 (1988) 1722-1727
89. Nakahara K., Ohno K., Hashimoto J., et al. Thymoma: results with complete resection and adjuvant postoperative irradiation in 141 consecutive patients. J Thorac Cardiovasc Surg 95 6 (1988) 1041-1047
90. Brambilla E., Travis W.D., Colby T.V., et al. The new World Health Organization classification of lung tumours. Eur Respir J 18 6 (2001) 1059-1068
91. Ito Y., Miyauchi A., Nakamura Y., et al. Clinicopathologic significance of intrathyroidal epithelial thymoma/carcinoma showing thymus-like differentiation: a collaborative study with member institutes of the Japanese Society of Thyroid Surgery. Am J Clin Pathol 127 2 (2007) 230-236
92. Meister M., Schirmacher P., Dienemann H., et al. Mutational status of the epidermal growth factor receptor (EGFR) gene in thymomas and thymic carcinomas. Cancer Lett 248 2 (2007) 186-191
93. Maruyama R., Suemitsu R., Okamoto T., et al. Persistent and aggressive treatment for thymic carcinoma. Results of a single-institute experience with 25 patients. Oncology 70 5 (2006) 325-329
94. Rieker R.J., Joos S., Mechtersheimer G., et al. COX-2 upregulation in thymomas and thymic carcinomas. Int J Cancer 119 9 (2006) 2063-2070
95. Lin J.T., Wei-Shu W., Yen C.C., et al. Stage IV thymic carcinoma: a study of 20 patients. Am J Med Sci 330 4 (2005) 172-175
96. Lucchi M., Ambrogi M.C., Duranti L., et al. Advanced stage thymomas and thymic carcinomas: results of multimodality treatments. Ann Thorac Surg 79 6 (2005) 1840-1844
97. Suzuki M., Ando S., Iida T., et al. Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma. Oncol Rep 13 6 (2005) 1127-1131
98. Strobel P., Bauer A., Puppe B., et al. Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: a retrospective analysis. J Clin Oncol 22 8 (2004) 1501-1509
99. Takeda S., Sawabata N., Inoue M., et al. Thymic carcinoma. Clinical institutional experience with 15 patients. Eur J Cardiothorac Surg 26 2 (2004) 401-406
100. Pan C.C., Chen P.C., Chou T.Y., et al. Expression of calretinin and other mesothelioma-related markers in thymic carcinoma and thymoma. Hum Pathol 34 11 (2003) 1155-1162
101. Tseng Y.L., Wang S.T., Wu M.H., et al. Thymic carcinoma: involvement of great vessels indicates poor prognosis. Ann Thorac Surg 76 4 (2003) 1041-1045
102. Giaccone G. Treatment of thymoma and thymic carcinoma. Ann Oncol 11 Suppl 3 (2000) 245-246
103. Takahashi K., Yoshida J., Nishimura M., et al. Thymic carcinoma. Outcome of treatment including surgical resection. Jpn J Thorac Cardiovasc Surg 48 8 (2000) 494-498
104. Marx A., and Muller-Hermelink H.K. Thymoma and thymic carcinoma. Am J Surg Pathol 23 6 (1999) 739-742
105. Blumberg D., Burt M.E., Bains M.S., et al. Thymic carcinoma: current staging does not predict prognosis. J Thorac Cardiovasc Surg 115 2 (1998) 303-308
106. Hishima T., Fukayama M., Hayashi Y., et al. Neuroendocrine differentiation in thymic epithelial tumors with special reference to thymic carcinoma and atypical thymoma. Hum Pathol 29 4 (1998) 330-338
107. Hsu N.Y., Lin J.W., Hsieh M.J., et al. Thymic lymphoepithelioma-like carcinoma associated with thymoma in a patient with ocular myasthenia. Scand Cardiovasc J 32 2 (1998) 105-107
108. Kuo T.T., and Chan J.K. Thymic carcinoma arising in thymoma is associated with alterations in immunohistochemical profile. Am J Surg Pathol 22 12 (1998) 1474-1481
109. Morikawa Y., Ishihara Y., Kawano I., et al. Cystic squamous cell carcinoma of the thyroid-a possible new subgroup of intrathyroidal epithelial thymoma. Endocr Pathol 6 1 (1995) 77-81
110. Hsu C.P., Chen C.Y., Chen C.L., et al. Thymic carcinoma. Ten years' experience in twenty patients. J Thorac Cardiovasc Surg 107 2 (1994) 615-620
111. Tsuchiya R., Koga K., Matsuno Y., et al. Thymic carcinoma: proposal for pathological TNM and staging. Pathol Int 44 7 (1994) 505-512
112. Kirchner T., Schalke B., Buchwald J., et al. Well-differentiated thymic carcinoma. An organotypical low-grade carcinoma with relationship to cortical thymoma. Am J Surg Pathol 16 12 (1992) 1153-1169
113. Wagner K.B., Khan A., Mir R., et al. Thymic carcinoma arising from long standing thymoma and presenting with pituitary metastases. Comput Med Imaging Graph 15 6 (1991) 411-414
114. Morinaga S., Sato Y., Shimosato Y., et al. Multiple thymic squamous cell carcinomas associated with mixed type thymoma. Am J Surg Pathol 11 12 (1987) 982-988
115. Herczeg E., and Kahn L.B. Primary thymic carcinoma. An unusual case originating in a lymphocytic rich thymoma. Virchows Arch A Pathol Anat Histopathol 409 2 (1986) 163-169
116. Shiraishi J., Nomori H., Orikasa H., et al. Atypical thymoma (WHO B3) with neuroendocrine differentiation: report of a case. Virchows Arch 449 2 (2006) 234-237
117. Cho K.J., Ha C.W., Koh J.S., et al. Thymic carcinoid tumor combined with thymoma-neuroendocrine differentiation in thymoma?. J Korean Med Sci 8 6 (1993) 458-463
118. Moran C.A., and Suster S. Neuroendocrine carcinomas (carcinoid tumor) of the thymus. A clinicopathologic analysis of 80 cases. Am J Clin Pathol 114 1 (2000) 100-110
119. Moran C.A., and Suster S. Primary neuroendocrine carcinoma (thymic carcinoid) of the thymus with prominent oncocytic features: a clinicopathologic study of 22 cases. Mod Pathol 13 5 (2000) 489-494
120. Moran C.A., and Suster S. Thymic neuroendocrine carcinomas with combined features ranging from well-differentiated (carcinoid) to small cell carcinoma. A clinicopathologic and immunohistochemical study of 11 cases. Am J Clin Pathol 113 3 (2000) 345-350
121. Baran J.L., Magro C.M., King M.A., et al. Atypical thymoma: a report of seven patients. Ann Thorac Surg 78 2 (2004) 411-416
122. Muller-Hermelink H.K., and Marx A. Pathological aspects of malignant and benign thymic disorders. Ann Med 31 Suppl 2 (1999) 5-14
123. Suster S., and Moran C.A. Primary thymic epithelial neoplasms: spectrum of differentiation and histological features. Semin Diagn Pathol 16 1 (1999) 2-17
124. Close P.M., Kirchner T., Uys C.J., et al. Reproducibility of a histogenetic classification of thymic epithelial tumours. Histopathology 26 4 (1995) 339-343
125. Quintanilla-Martinez L., Wilkins Jr. E.W., Ferry J.A., et al. Thymoma-morphologic subclassification correlates with invasiveness and immunohistologic features: a study of 122 cases. Hum Pathol 24 9 (1993) 958-969
126. Suster S. Recent advances in the application of immunohistochemical markers for the diagnosis of soft tissue tumors. Semin Diagn Pathol 17 3 (2000) 225-235
127. Moran C.A., Wick M.R., and Suster S. The role of immunohistochemistry in the diagnosis of malignant mesothelioma. Semin Diagn Pathol 17 3 (2000) 178-183
128. Nonaka D., Henley J.D., Chiriboga L., et al. Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. Am J Surg Pathol 31 7 (2007) 1038-1044
129. Kim D.J., Yang W.I., Choi S.S., et al. Prognostic and clinical relevance of the World Health Organization schema for the classification of thymic epithelial tumors: a clinicopathologic study of 108 patients and literature review. Chest 127 3 (2005) 755-761
130. Wright C.D., Wain J.C., Wong D.R., et al. Predictors of recurrence in thymic tumors: importance of invasion, World Health Organization histology, and size. J Thorac Cardiovasc Surg 130 5 (2005) 1413-1421
131. Park M.S., Chung K.Y., Kim K.D., et al. Prognosis of thymic epithelial tumors according to the new World Health Organization histologic classification. Ann Thorac Surg 78 3 (2004) 992-997
132. Rea F., Marulli G., Girardi R., et al. Long-term survival and prognostic factors in thymic epithelial tumours. Eur J Cardiothorac Surg 26 2 (2004) 412-418
133. Nakagawa K., Asamura H., Matsuno Y., et al. Thymoma: a clinicopathologic study based on the new World Health Organization classification. J Thorac Cardiovasc Surg 126 4 (2003) 1134-1140