Oncological Significance of WHO Histological Thymoma Classification: A Clinical Study Based on 286 Patients

Japanese Journal of Thoracic and Cardiovascular Surgery

Volumn 50, Issue 5, 2002, Pages 189-194

  Okumura, Meinoshin ^a,b   Ohta, Mitsunori ^a,b   Miyoshi, Shinichiro ^a,b   Mori, Takashi ^b   Yasumitsu, Tsutomu ^b   Nakahara, Kazuya ^b   Iuchi, Keiji ^b   Tada, Hiroto ^b   Maeda, Hajime ^b   Matsuda, Hikaru ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Masaoka staging; Thymic epithelial tumor; Thymoma; WHO histological classification

Indexed keywords

ADOLESCENT; ADULT; AGE; AGED; CANCER INVASION; CANCER MORTALITY; CANCER STAGING; CLINICAL FEATURE; CONFERENCE PAPER; FEMALE; GENDER; GREAT BLOOD VESSEL; HISTOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MASAOKA STAGING; MULTIVARIATE ANALYSIS; MYASTHENIA GRAVIS; ONCOLOGY; POSTOPERATIVE PERIOD; PROGNOSIS; SURVIVAL RATE; THYMOMA; TUMOR CLASSIFICATION; WORLD HEALTH ORGANIZATION; ARTICLE; CLASSIFICATION; MIDDLE AGED; MORTALITY; PATHOLOGY; RETRACTED ARTICLE;

ADOLESCENT; ADULT; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; SURVIVAL RATE; THYMOMA; THYMUS NEOPLASMS; WORLD HEALTH ORGANIZATION;

EID: 0036580514     PISSN: 13444964     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03032284     Document Type: Conference Paper

References (23)

1. Masaoka A, Monden Y, Nakahara K, Tanioka T. Follow-up study of thymomas with special reference to their clinical stages. Cancer 1981; 48: 2485-92.
2. Nakahara K, Ohno K, Hashimoto J, Maeda H, Miyoshi S, Sakurai M, et al. Thymoma: results with complete resection and adjuvant postoperative irradiation in 141 consecutive patients. J Thorac Cardiovasc Surg 1988; 95: 1041-7.
3. Regnard J-F, Magdeleinat P, Dromer C, Dulmet E, De Montpreville V, Levi J-F, et al. Prognostic factors and long-term results after thymoma resection: a series of 307 patients. J Thorac Cardiovasc Surg 1996; 112: 376-84.
4. Maggi G, Casadio C, Cavallo A, Cianci R, Molinatti M, Ruffini E. Thymoma: results of 241 operated cases. Ann Thorac Surg 1991; 51: 152-6.
5. Wilkins, KB, Sheikh, E, Green, R, Patel, M, George, S, Takano, M, et al. Clinical and pathologic predictors of survival in patients with thymoma. Ann Surg 1999; 230: 562-74.
6. Wilkins Jr EW, Edmunds LH, Castleman B. Cases of thymoma at the Massachusetts General Hospital. J Thorac Cardiovasc Surg 1966; 52: 322-30.
7. Monden Y, Nakahara K, Kagotani K, Fujii Y, Masaoka A, Kawashima Y. Myasthenia gravis with thymoma: Analysis of and postopertive prognosis for 65 patients with thymomatous myasthenia gravis. Ann Thorac Surg 1984; 38: 46-52.
8. Wilkins Jr EW, Grillo HC, Scannell JG, Moncure AC, Mathisen DJ. Role of staging in prognosis and management of thymoma. Ann Thorac Surg 1991; 51: 888-92.
9. Blumberg D, Port JL, Weksler B, Delgado R, Rosai J, Bains MS, et al. Thymoma: a multivariate analysis of factors predicting survival. Ann Thorac Surg 1995; 60: 908-14.
10. Okumura M, Miyoshi S, Takeuchi Y, Yoon H-E, Minami M, Takeda S, et al. Results of surgical treatment of thymomas with special reference to the involved organs. J Thorac Cardiovasc Surg 1999; 117: 605-13.
11. Rosai J, Levine GD. Tumors of the thymus. Atlas of tumor pathology, 2nd series, Fascicle 13. Washington, D, C.: Armed Forces Institute of Pathology, 1976.
12. Shimosato Y, Mukai K. Tumors of the mediastinum. Atlas of tumor pathology, 3rd series, Fascicle 21. Washington, D, C.: Armed Forces Institute of Pathology, 1997.
13. Kirchner T, Schalke B, Marx A, Müller-Hermelink HK. Evaluation of prognostic features in thymic epithelial tumors. Thymus 1989; 14: 195-203.
14. Pescarmona E, Rendima EA, Venuta F, D'Arcangelo E, Pagani M, Ricci C, et al. Analysis of prognostic factors and clinicopathological staging of thymomas. Ann Thorac Surg 1990; 50: 534-8.
15. Quintanilla-Martinez L, Wilkins EW Jr, Choi N, Efird J, Hug E, Harris NL. Thymoma. Histologic subclassification is an independent prognostic factor. Cancer 1994; 74: 606-17.
16. Landinois D, Rechsteiner R, Laeng RH, Gugger M, Betticher D, von Briel C, et al. Prognostic relevance of Masaoka and Müller-Hermelink classification in patients with thymic tumors. Ann Thorac Surg 2000; 69: 1550-5.
17. Suster S, Moran CA. Thymoma, atypical thymoma, and thymic carcinoma. A novel conceptual approach to the classification of thymic epithelial neoplasms. Am J Clin Pathol 1999; 111: 826-33.
18. Harris NL, Müller-Hermelink H-K. Thymoma classification. A siren's song of simplicity. Am J Clin Pathol 1999; 112: 299-303.
19. Kornstein MJ. Thymoma classification: my opinion. Am J Clin Pathol 1999; 112: 304-7.
20. Suster S, Moran CA. Thymoma classification: the ride of the valkyries? Am J Clin Pathol 1999; 112: 308-10.
21. Rosai J, Sobin LH. Histological typing of tumours of the thymus. International histological classification of tumours, 2nd edition. New York, Berlin: Springer, 1999.
22. Okumura M, Miyoshi S, Fujii Y, Takeuchi Y, Shiono H, Inoue M, et al. Clinical and functional significance of WHO classification on human thymic epithelial neoplasms: a study of 146 consecutive tumors. Am J Surg Pathol 2001; 25: 103-10.
23. Zettl A, Strobel P, Wagner K, Katzenberger T, Ott G, Rosenwald A, et al. Recurrent genetic aberations in thymoma and thymic carcinoma. Am J Pathol 2000; 157: 257-66.