Small-molecule inhibitors of sodium iodide symporter function

ChemBioChem

Volumn 9, Issue 6, 2008, Pages 889-895

  Lecat Guillet, Nathalie ^a   Merer, Goulven ^a   Lopez, Roman ^a   Pourcher, Thierry ^b   Rousseau, Bernard ^a   Ambroise, Yves ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

Biological activity; High throughput screening; Inhibitors; Membrane proteins; Sodium iodide symporter

Indexed keywords

ANTITHYROID AGENT; SODIUM IODIDE SYMPORTER; SODIUM IODIDE SYMPORTER INHIBITOR; UNCLASSIFIED DRUG; COTRANSPORTER; IODIDE;

ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; THYROID DISEASE; CELL LINE; CELL MEMBRANE POTENTIAL; CELL SURVIVAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; FLUORESCENCE; IC 50; METABOLISM; MOLECULAR LIBRARY; REPRODUCIBILITY; TIME;

CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE; HUMANS; INHIBITORY CONCENTRATION 50; IODIDES; MEMBRANE POTENTIALS; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES; SYMPORTERS; TIME FACTORS;

EID: 44049107138     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700682     Document Type: Article

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