The Na+-I- cotransporter of the thyroid: Characterisation of new inhibitors

Pflugers Archiv European Journal of Physiology

Volumn 435, Issue 2, 1998, Pages 259-266

  Vroye, L ^a   Beauwens, R ^a   Van Sande, J ^a   Daloze, D ^a   Braekman, J C ^a   Golstein, P E ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

5 (N,N Hexamethylene)amiloride; Dysidenin; Econazole; Iodide transport; Plasma membrane vesicle

Indexed keywords

5 (N,N HEXAMETHYLENE)AMILORIDE; ANION CHANNEL; DYSIDENIN; ECONAZOLE; IODIDE; SODIUM; SODIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

AMILORIDE; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CATTLE; CELL MEMBRANE; ECONAZOLE; IODIDES; IODINE RADIOISOTOPES; KINETICS; LIPOSOMES; MARINE TOXINS; MEMBRANE PROTEINS; SYMPORTERS; THIAZOLES; THYROID GLAND;

EID: 0031909918     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050510     Document Type: Article

References (28)

1. Bagchi N, Fawcett DM (1973) Role of sodium ion in active transport of iodide by cultured thyroid cells. Biochim Biophys Acta 318:235-251
2. Berteloot A, Semenza G (1990) Advantages and limitations of vesicles for the characterization and the kinetic analysis of transport systems. Methods Enzymol 192:409-437
3. Cabantchik ZI, Greger R (1992) Chemical probes for anion transporters of mammalian cell membranes. Am J Physiol 262:C803-827
4. Carrasco N (1993) Iodide transport in the thyroid gland. Biochim Biophys Acta 1154:65-82
5. Carruthers A (1990) Facilitated diffusion of glucose. Physiol Rev 70:1135-1176
6. Chambard M, Verrier B, Gabrion J, Mauchamp J (1983) Polarization of thyroid cells in culture: evidence for the basolateral localization of the iodide "pump" and of the thyroid-stimulating hormone receptor-adenyl cyclase complex. J Cell Biol 96:1172-1177
7. Charles C, Braekman JC, Daloze D, Tursch B, Karlsson R (1978) Isodysidenin, a further hexachlorinated metabolite from the sponge Dysidea herbacea. Tetrahedron Lett 19:1519-1520
8. 4 cells. Am J Physiol 253:C199-C204
9. Dai G, Levy O, Carrasco N (1996) Cloning and characterization of the thyroid iodide transporter. Nature 379:458-460
10. Dixon M, Webb EC (eds) (1979) Enzyme inhibition and activation. In: Enzymes, vol. VIII: enzyme inhibition and activation. Longman Group Limited London, pp 332-468
11. Golstein PE, Abramow M, Dumont JE, Beauwens R (1992) The iodide channel of the thyroid: a plasma membrane vesicle study. Am J Physiol 263:C590-C597
12. Golstein PE, Sener A, Beauwens R (1995) The iodide channel of the thyroid II: selective iodide conductance inserted into liposomes. Am J Physiol 268:C111-C118
13. Hediger MA, Rhoads DB (1994) Molecular physiology of sodium-glucose cotransporters. Physiol Rev 74:993-1026
14. Hopfer U, Nelson K, Perrotto J, Isselbacher KJ (1973) Glucose transport in isolated brush border membrane from rat small intestine. J Biol Chem 248:25-32
15. - symporter by harmaline and 3-amino-1-methyl-5H-pyrido(4,3-b)indole acetate in thyroid cells and membrane vesicles. Eur J Biochem 200:203-207
16. Kinne R, Kinne KH (eds) (1985) Renal biochemistry: cells, membranes, molecules. Transport function of renal cell membranes: sodium cotransport systems. Elsevier, Amsterdam, pp 99-141
17. McManus M, Serhan C, Jackson P, Strange K (1994) Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. Am J Physiol 267:C266-C271
18. Nakamura Y, Ohtaki S, Yamazaki I (1988) Molecular mechanism of iodide transport by thyroid plasmalemmal vesicles: cooperative sodium activation and asymmetrical affinities for the ions on the outside and inside of the vesicles. J Biochem 104:544-549
19. Nilsson M, Björkman U, Ekholm R, Ericson LA (1992) Polarized efflux of iodide in porcine thyrocytes occurs via a cAMP-regulated iodide channel in the apical plasma membrane. Acta Endocrinol 126:67-74
20. - transport system in plasma membrane vesicles from thyroid glands. Biochim Biophys Acta 896:263-274
21. - symporter in thyroid follicles in culture. Biochem Biophys Res Commun 204:1265-1271
22. Van Sande J, Deneubourg F, Beauwens R, Braekman JC, Daloze D, Dumont JE (1990) Inhibition of iodide transport in thyroid cells by dysidenin, a marine toxin, and some of its analogs. Mol Pharmacol 37:583-589
23. Vassart GE, Dumont JE, Refetoff S (1995) Thyroid disorders. In: Scriver CR, Beaudet AL, Sly WL, Valle D (eds) Metabolic and molecular basis of inherited diseases. McGraw-Hill, New York, pp 2883-2928
24. Weiss SJ, Philp NJ, Grollman EF (1984) Iodide transport in a continuous line of cultured cells from rat thyroid. Endocrinology 114:1090-1098
25. Wiechelman K, Braun R, Fitzpatrick J (1988) Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation. Anal Biochem 175: 231-237
26. Wolff J (1964) Transport of iodide and other anions in the thyroid gland. Physiol Rev 44:45-90
27. Wolff J, Maurey JR (1963) Thyroidal iodide transport: IV. The role of anion size. Biochim Biophys Acta 69:58-67
28. +/glucose cotransporter. Annu Rev Physiol 55:575-589